| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 184 | 22 | 4 | 4 |
| Binding ≤ 1μM | 148 | 13 | 4 | 4 |
| Functional ≤ 10μM | 41 | 1 | 2 | 1 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_247174 | Eicosanoids | Rattus norvegicus |
| REACT_194948 | Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | Rattus norvegicus |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| THAS_HUMAN | P24557 | CHEMBL1835 | Thromboxane-A Synthase, Human | 972 | 36 | 9 | 8 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| THAS-1-E | Thromboxane-A Synthase (cluster #1 Of 3), Eukaryotic | 873 | 20 | 6 | 6 |
| THAS-2-E | Thromboxane-A Synthase (cluster #2 Of 3), Eukaryotic | 158 | 9 | 1 | 1 |
| THAS-3-E | Thromboxane-A Synthase (cluster #3 Of 3), Eukaryotic | 111 | 26 | 2 | 1 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| TA2R_HUMAN | P21731 | CHEMBL2069 | Thromboxane A2 Receptor, Human | 57 |
| THAS_HUMAN | P24557 | CHEMBL1835 | Thromboxane-A Synthase, Human | 20 |
| Z50587 | Z50587 | CHEMBL372 | Homo Sapiens | 18 |
| LOX5_RAT | P12527 | CHEMBL312 | Arachidonate 5-lipoxygenase, Rat | 17 |
| Z50512 | Z50512 | CHEMBL369 | Cavia Porcellus | 15 |
| PGH2_HUMAN | P35354 | CHEMBL230 | Cyclooxygenase-2, Human | 4 |
| PGH1_HUMAN | P23219 | CHEMBL221 | Cyclooxygenase-1, Human | 2 |
| Z50592 | Z50592 | CHEMBL374 | Oryctolagus Cuniculus | 1 |