UCSF

Human Immunodeficiency Virus 1 (11 Compounds)

Swissprot:
Z50607
Stitch:
Z50607
UniProt:
Z50607
ChEMBL:
CHEMBL378

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 11 1 2 1
Binding ≤ 1μM 7 0 2 0
Functional ≤ 10μM 9,012 399 133 122
ADME/T ≤ 10μM 0 0 0 0

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
Z80295 Z80295 CHEMBL388 MT4 (Lymphocytes) 690
Z50658 Z50658 CHEMBL380 Human Immunodeficiency Virus 2 410
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 373
Z50677 Z50677 CHEMBL613758 Human Immunodeficiency Virus 224
Q72547_9HIV1 Q72547 CHEMBL247 Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 160
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 152
Z80076 Z80076 CHEMBL614548 CEM-SS (T-cell Leukemia) 129
CXCR4_HUMAN P61073 CHEMBL2107 C-X-C Chemokine Receptor Type 4, Human 115
Z50606 Z50606 CHEMBL613497 Hepatitis B Virus 101
Z80897 Z80897 CHEMBL614806 H9 (T-lymphoid Cells) 87
Z80294 Z80294 CHEMBL614184 MT2 (Lymphocytes) 70
Z80052 Z80052 CHEMBL614533 C8166 (Leukemic T-cells) 58
Z50602 Z50602 CHEMBL377 Human Herpesvirus 1 57
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 53
Z50515 Z50515 CHEMBL370 Human Herpesvirus 2 48
Z50527 Z50527 CHEMBL613132 Human Herpesvirus 3 42
Z50609 Z50609 CHEMBL613499 Simian Immunodeficiency Virus 42
Z50737 Z50737 CHEMBL612359 Human Immunodeficiency Virus 3 37
Z80565 Z80565 CHEMBL614247 U-87 MG (Glioblastoma Cells) 37
Z80737 Z80737 CHEMBL614372 C3H/3T3 (Embryonic Fibroblast Cells) 37
Z50530 Z50530 CHEMBL371 Human Herpesvirus 5 33
Z50587 Z50587 CHEMBL372 Homo Sapiens 33
Z80526 Z80526 CHEMBL612544 SW480 (Colon Adenocarcinoma Cells) 31
TAT_HV112 P04326 CHEMBL4609 Human Immunodeficiency Virus Type 1 Tat Protein, Hv112 29
Z50612 Z50612 CHEMBL613501 Moloney Murine Sarcoma Virus 27
Z80071 Z80071 CHEMBL614028 CEM-0 (T-cell Leukemia) 25
Z50600 Z50600 CHEMBL613493 Vaccinia Virus 23
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral Blood Mononuclear Cells) 21
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 18
Z80583 Z80583 CHEMBL391 Vero (Kidney Cells) 18
Z50668 Z50668 CHEMBL612320 Human Coxsackievirus B4 17
Z80110 Z80110 CHEMBL613507 CV-1 (Kidney Cells) 17
Z50608 Z50608 CHEMBL613498 Human Immunodeficiency Virus Type 1 (RF/HAT ISOLATE) 13
Z80107 Z80107 CHEMBL614564 COS-7 (Kidney Cells) 13
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 12
Z80285 Z80285 CHEMBL614177 MOLT-4 (Acute T-lymphoblastic Leukemia Cells) 12
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 12
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 10
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 9
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 9
Z80077 Z80077 CHEMBL614044 CEM-TK(-) 8
Z80078 Z80078 CHEMBL614029 CEM-TK(+) 8
Z101839 Z101839 CHEMBL612775 HIV-1 M:B_Lai 7
Z50420 Z50420 CHEMBL612851 Trypanosoma Brucei Brucei 7
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 7
Z102020 Z102020 CHEMBL613016 Porcine Endogenous Retrovirus 6
Z50611 Z50611 CHEMBL613500 Moloney Murine Leukemia Virus 6
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 6
Z80949 Z80949 CHEMBL614821 Hepatoma Cell Line 6
TBB2B_BOVIN Q6B856 CHEMBL3394 Tubulin Beta Chain, Bovin 5
Z50517 Z50517 CHEMBL613123 Human Herpesvirus 5 Strain AD169 5
Z80073 Z80073 CHEMBL614545 CEM-c113 5
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 5
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 5
Z80418 Z80418 CHEMBL612557 RAW264.7 (Monocytic-macrophage Leukemia Cells) 5
Z80490 Z80490 CHEMBL614923 SK-MES-1 5
Z80566 Z80566 CHEMBL612794 U-937 (Histiocytic Lymphoma Cells) 5
Z80653 Z80653 CHEMBL613105 9L (Glioma Cells) 5
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 5
NR1H4_HUMAN Q96RI1 CHEMBL2047 Bile Acid Receptor FXR, Human 4
PTAFR_HUMAN P25105 CHEMBL250 Platelet Activating Factor Receptor, Human 4
TBB1_HUMAN Q9H4B7 CHEMBL1915 Tubulin Beta-1 Chain, Human 4
Z50038 Z50038 CHEMBL612328 Plasmodium Yoelii Yoelii 4
Z50518 Z50518 CHEMBL613124 Human Herpesvirus 4 4
Z50614 Z50614 CHEMBL613551 Human T-lymphotropic Virus 1 4
Z50725 Z50725 CHEMBL612348 Trypanosoma Brucei Rhodesiense 4
Z80070 Z80070 CHEMBL614543 CEM_SS 4
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 4
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 4
Z80954 Z80954 CHEMBL614071 HFF (Foreskin Fibroblasts) 4
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 4
GPBAR_HUMAN Q8TDU6 CHEMBL5409 G-protein Coupled Bile Acid Receptor 1, Human 3
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 3
Q862F3_BOVIN Q862F3 CHEMBL4262 Tubulin Alpha Chain, Bovin 3
Q862L2_BOVIN Q862L2 CHEMBL3752 Tubulin Alpha-1 Chain, Bovin 3
TBB3_HUMAN Q13509 CHEMBL2597 Tubulin Beta-3 Chain, Human 3
TBB4A_HUMAN P04350 CHEMBL3838 Tubulin Beta-4 Chain, Human 3
TBB4B_HUMAN P68371 CHEMBL1848 Tubulin Beta-2 Chain, Human 3
TBB8_HUMAN Q3ZCM7 CHEMBL4024 Tubulin Beta-8 Chain, Human 3
Z101682 Z101682 CHEMBL613915 BK Polyomavirus 3
Z50594 Z50594 CHEMBL375 Mus Musculus 3
Z50643 Z50643 CHEMBL379 Hepatitis C Virus 3
Z50651 Z50651 CHEMBL613739 Vesicular Stomatitis Virus 3
Z80064 Z80064 CHEMBL382 CCRF-CEM (T-cell Leukemia) 3
Z80106 Z80106 CHEMBL614563 COS-1 (Kidney Cells) 3
Z80414 Z80414 CHEMBL614628 Raji (B-lymphoblastic Cells) 3
Z80485 Z80485 CHEMBL614919 SK-MEL-28 (Melanoma Cells) 3
Z80550 Z80550 CHEMBL614612 TZM (Cervical Carcinoma Cells) 3
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 3
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 3
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 2
Q7ZJM1_9HIV1 Q7ZJM1 CHEMBL3471 Human Immunodeficiency Virus Type 1 Integrase, 9hiv1 2
TBA1A_RAT P68370 CHEMBL4139 Tubulin Alpha-1 Chain, Rat 2
Z102015 Z102015 CHEMBL613013 Plasmodium Vivax 2
Z102256 Z102256 CHEMBL613450 Plasma 2
Z50417 Z50417 CHEMBL612848 Leishmania Infantum 2
Z50426 Z50426 CHEMBL612856 Plasmodium Falciparum (isolate K1 / Thailand) 2
Z50459 Z50459 CHEMBL367 Leishmania Donovani 2
Z50466 Z50466 CHEMBL368 Trypanosoma Cruzi 2
Z50599 Z50599 CHEMBL612672 Cowpox Virus 2
Z50604 Z50604 CHEMBL613495 Murid Herpesvirus 1 2
Z50641 Z50641 CHEMBL613730 West Nile Virus 2
Z50652 Z50652 CHEMBL613740 Influenza A Virus 2
Z50664 Z50664 CHEMBL613748 Rauscher Murine Leukemia Virus 2
Z50678 Z50678 CHEMBL612679 Respiratory Syncytial Virus 2
Z80002 Z80002 CHEMBL614075 1A9 (Ovarian Adenocarcinoma Cells) 2
Z80054 Z80054 CHEMBL614058 Caco-2 (Colon Adenocarcinoma Cells) 2
Z80125 Z80125 CHEMBL613508 DU-145 (Prostate Carcinoma) 2
Z80150 Z80150 CHEMBL614576 H9c2 (Cardiomyoblast Cells) 2
Z80164 Z80164 CHEMBL614580 HT-1080 (Fibrosarcoma Cells) 2
Z80244 Z80244 CHEMBL614335 MDA-MB-468 (Breast Adenocarcinoma) 2
Z80291 Z80291 CHEMBL614181 MRC5 (Embryonic Lung Fibroblast Cells) 2
Z80354 Z80354 CHEMBL614213 OVCAR-3 (Ovarian Adenocarcinoma Cells) 2
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 2
Z80427 Z80427 CHEMBL614879 RKO (Colon Carcinoma) 2
Z80516 Z80516 CHEMBL614940 SUP-T1 2
Z80557 Z80557 CHEMBL614246 U1 2
Z80678 Z80678 CHEMBL614270 AMML Cell Line 2
Z80683 Z80683 CHEMBL614272 ATH8 Cell Line 2
Z80777 Z80777 CHEMBL614800 CML/BC Cell Line 2
Z80819 Z80819 CHEMBL614484 J774.2 2
Z81024 Z81024 CHEMBL396 NCI-H460 (Non-small Cell Lung Carcinoma) 2
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 2
Z81244 Z81244 CHEMBL614123 J774 (Macrophage Cells) 2
Z81335 Z81335 CHEMBL612263 HCT-15 (Colon Adenocarcinoma Cells) 2
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 1
CATD_HUMAN P07339 CHEMBL2581 Cathepsin D, Human 1
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 1
CXCR4_MACMU P79394 CHEMBL1250366 C-X-C Chemokine Receptor Type 4, Macmu 1
CXCR4_MOUSE P70658 CHEMBL1250365 C-X-C Chemokine Receptor Type 4, Mouse 1
CXCR4_RAT O08565 CHEMBL5556 C-X-C Chemokine Receptor Type 4, Rat 1
LASR_PSEAE P25084 CHEMBL1075207 Transcriptional Activator Protein LasR, Pseae 1
MDR3_MOUSE P21447 CHEMBL2573 P-glycoprotein 3, Mouse 1
Q9RMS5_PSEAI Q9RMS5 CHEMBL1075213 PhzR, Pseai 1
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 1
TBA1A_PIG P02550 CHEMBL3658 Tubulin Alpha Chain, Pig 1
TBA4A_HUMAN P68366 CHEMBL2070 Tubulin Alpha-1 Chain, Human 1
TBB5_HUMAN P07437 CHEMBL5444 Tubulin Beta-5 Chain, Human 1
TRPA1_HUMAN O75762 CHEMBL6007 Transient Receptor Potential Cation Channel Subfamily A Member 1, Human 1
Z100499 Z100499 CHEMBL612575 SARS Coronavirus 1
Z100695 Z100695 CHEMBL612587 WRL68 (Embryonic Hepatoma Cells) 1
Z100757 Z100757 CHEMBL612570 SW1573 (Lung Carcinoma Cells) 1
Z101697 Z101697 CHEMBL613332 Camelpox Virus 1
Z101779 Z101779 CHEMBL612728 Ectromelia Virus Moscow 1
Z101829 Z101829 CHEMBL612769 HBV Genotype D 1
Z101843 Z101843 CHEMBL613202 Human Coxsackievirus B2 1
Z101973 Z101973 CHEMBL613240 Paracentrotus Lividus 1
Z102131 Z102131 CHEMBL613167 Vaccinia Virus Copenhagen 1
Z102132 Z102132 CHEMBL613168 Vaccinia Virus WR 1
Z103192 Z103192 CHEMBL1075362 Trypanosoma Evansi 1
Z103202 Z103202 CHEMBL1075387 8505C 1
Z103203 Z103203 CHEMBL1075388 A375 1
Z103205 Z103205 CHEMBL1075390 A431 1
Z50378 Z50378 CHEMBL612640 Mycobacterium Intracellulare 1
Z50418 Z50418 CHEMBL612849 Trypanosoma Brucei 1
Z50436 Z50436 CHEMBL365 Filobasidiella Neoformans 1
Z50442 Z50442 CHEMBL366 Candida Albicans 1
Z50472 Z50472 CHEMBL612888 Toxoplasma Gondii 1
Z50529 Z50529 CHEMBL613134 Cytomegalovirus 1
Z50590 Z50590 CHEMBL613488 Sus Scrofa 1
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1
Z50624 Z50624 CHEMBL613715 Human Adenovirus Type 2 1
Z50636 Z50636 CHEMBL613725 Sindbis Virus 1
Z50657 Z50657 CHEMBL613744 Feline Immunodeficiency Virus 1
Z50681 Z50681 CHEMBL613761 Duck Hepatitis B Virus 1
Z50755 Z50755 CHEMBL612370 Anas Sp. 1
Z80024 Z80024 CHEMBL614518 A9 (Fibroblast Cells) 1
Z80025 Z80025 CHEMBL614519 ACHN (Renal Adenocarcinoma Cells) 1
Z80035 Z80035 CHEMBL381 B16 (Melanoma Cells) 1
Z80053 Z80053 CHEMBL612566 CA46 (Burkitts Lymphoma Cells) 1
Z80079 Z80079 CHEMBL614549 CEM-V 1
Z80096 Z80096 CHEMBL614559 CHO-TAX 5-6 1
Z80097 Z80097 CHEMBL614560 CHO-VV 3-2 1
Z80120 Z80120 CHEMBL614285 DLD-1 (Colon Adenocarcinoma Cells) 1
Z80121 Z80121 CHEMBL614286 DMS-79 (Small Cell Lung Carcinoma Cells) 1
Z80169 Z80169 CHEMBL614039 Huh-7 (Hepatocellular Carcinoma) 1
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 1
Z80269 Z80269 CHEMBL614354 MKN-45 (Gastric Adenocarcinoma Cells) 1
Z80282 Z80282 CHEMBL614174 MO/Mphi 1
Z80284 Z80284 CHEMBL614176 MOLT-3 (T-lymphoblastic Leukemia Cells) 1
Z80384 Z80384 CHEMBL614233 PBL (Peripheral Blood Lymphocytes) 1
Z80420 Z80420 CHEMBL614632 RBL-2H3 (Basophilic Leukemia Cells) 1
Z80466 Z80466 CHEMBL614907 SF268 1
Z80470 Z80470 CHEMBL614909 SGC-7901 (Gastric Carcinoma Cells) 1
Z80472 Z80472 CHEMBL612542 SiHa (Cervical Squamous Cell Carcinoma) 1
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast Adenocarcinoma) 1
Z80482 Z80482 CHEMBL614917 SK-MEL-2 (Melanoma Cells) 1
Z80493 Z80493 CHEMBL614925 SK-OV-3 (Ovarian Carcinoma Cells) 1
Z80548 Z80548 CHEMBL614245 THP-1 (Acute Monocytic Leukemia Cells) 1
Z80608 Z80608 CHEMBL614393 ZR-75-1 (Breast Carcinoma Cells) 1
Z80612 Z80612 CHEMBL612818 2008 (Ovarian Carcinoma Cells) 1
Z80662 Z80662 CHEMBL614259 AA5 1
Z80688 Z80688 CHEMBL614797 B(EBV+) Cell Line 1
Z80697 Z80697 CHEMBL614279 Bel-7402 (Hepatoma Cells) 1
Z80711 Z80711 CHEMBL613829 NCI/ADR-RES (Breast Carcinoma Cells) 1
Z80720 Z80720 CHEMBL614365 Burkitts Lymphoma Cells 1
Z80721 Z80721 CHEMBL614366 BxT Cell Line 1
Z80760 Z80760 CHEMBL614779 CFU-GM Cell Line 1
Z80847 Z80847 CHEMBL612250 FaDu (Pharyngeal Carcinoma Cells) 1
Z80852 Z80852 CHEMBL614069 A-431 (Epidermoid Carcinoma Cells) 1
Z80865 Z80865 CHEMBL612253 GHOST CXCR4 Cell Line 1
Z80866 Z80866 CHEMBL612707 GLC4 Cell Line 1
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 1
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 1
Z80947 Z80947 CHEMBL614820 Hepatoblastoma Cell Line 1
Z81054 Z81054 CHEMBL613977 SF-268 (Glioblastoma Cells) 1
Z81135 Z81135 CHEMBL614793 L6 (Skeletal Muscle Myoblast Cells) 1
Z81186 Z81186 CHEMBL614097 LS174T (Colon Adencocarcinoma Cells) 1
Z81223 Z81223 CHEMBL614115 M Cell Line 1
Z81281 Z81281 CHEMBL614997 NCI-H23 (Non-small Cell Lung Carcinoma Cells) 1
Z81283 Z81283 CHEMBL614387 NCI-H522 (Non-small Cell Lung Carcinoma Cells) 1
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 1