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  • Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
    UCSF
    ZINC Item Suppliers, Protomers, & Similar Substances

    Analogs

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    Vendors

    Activity (Go SEA)

    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    ADCY1-1-E Brain Adenylate Cyclase 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 254 0.23 Binding ≤ 10μM
    ADCY2-2-E Adenylate Cyclase Type II (cluster #2 Of 2), Eukaryotic Eukaryotes 254 0.23 Binding ≤ 10μM
    ADCY3-2-E Adenylate Cyclase Type III (cluster #2 Of 2), Eukaryotic Eukaryotes 254 0.23 Binding ≤ 10μM
    ADCY4-2-E Adenylate Cyclase Type IV (cluster #2 Of 2), Eukaryotic Eukaryotes 254 0.23 Binding ≤ 10μM
    ADCY5-2-E Adenylate Cyclase Type V (cluster #2 Of 2), Eukaryotic Eukaryotes 254 0.23 Binding ≤ 10μM
    ADCY6-2-E Adenylate Cyclase Type VI (cluster #2 Of 2), Eukaryotic Eukaryotes 254 0.23 Binding ≤ 10μM
    ADCY7-2-E Adenylate Cyclase Type VII (cluster #2 Of 2), Eukaryotic Eukaryotes 254 0.23 Binding ≤ 10μM
    ADCY8-1-E Adenylate Cyclase Type VIII (cluster #1 Of 2), Eukaryotic Eukaryotes 254 0.23 Binding ≤ 10μM
    ADCY9-2-E Adenylate Cyclase Type IX (cluster #2 Of 2), Eukaryotic Eukaryotes 254 0.23 Binding ≤ 10μM
    GIPR-1-E Gastric Inhibitory Polypeptide Receptor (cluster #1 Of 1), Eukaryotic Eukaryotes 28 0.26 Binding ≤ 10μM
    GLP1R-1-E Glucagon-like Peptide Receptor (cluster #1 Of 1), Eukaryotic Eukaryotes 1000 0.21 Binding ≤ 10μM
    GLP1R-1-E Glucagon-like Peptide Receptor (cluster #1 Of 1), Eukaryotic Eukaryotes 2536 0.20 Binding ≤ 10μM
    GLR-1-E Glucagon Receptor (cluster #1 Of 2), Eukaryotic Eukaryotes 23 0.27 Binding ≤ 10μM
    GLR-1-E Glucagon Receptor (cluster #1 Of 2), Eukaryotic Eukaryotes 47 0.26 Binding ≤ 10μM
    GLR-1-E Glucagon Receptor (cluster #1 Of 2), Eukaryotic Eukaryotes 63 0.25 Binding ≤ 10μM
    GIPR-1-E Gastric Inhibitory Polypeptide Receptor (cluster #1 Of 1), Eukaryotic Eukaryotes 1300 0.21 Functional ≤ 10μM
    GLR-1-E Glucagon Receptor (cluster #1 Of 1), Eukaryotic Eukaryotes 21 0.27 Functional ≤ 10μM
    GLR-1-E Glucagon Receptor (cluster #1 Of 1), Eukaryotic Eukaryotes 140 0.24 Functional ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 5.77 12.44 -62.71 2 8 -1 111 562.609 11

    Analogs

    5720973
    5720973
    5949080
    5949080

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    Vendors

    Activity (Go SEA)

    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    GLR-1-E Glucagon Receptor (cluster #1 Of 2), Eukaryotic Eukaryotes 4800 0.31 Binding ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.60 -1.06 -17.71 2 5 0 70 320.348 4

    Analogs

    485315
    485315
    498343
    498343

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    Vendors

    And 6 More

    Activity (Go SEA)

    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    GLR-1-E Glucagon Receptor (cluster #1 Of 2), Eukaryotic Eukaryotes 4900 0.31 Binding ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.79 -1.31 -17.14 2 5 0 70 320.348 4

    Analogs

    5330080
    5330080

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    Vendors

    And 11 More

    Activity (Go SEA)

    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    GLR-1-E Glucagon Receptor (cluster #1 Of 2), Eukaryotic Eukaryotes 1800 0.37 Binding ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.78 -1.43 -16.44 2 4 0 61 290.322 3

    Parameters Provided:

    target.name = GLR-1-E
    target.type = B10
    page.format = summary
    page.num = 1
    filter.purchasability = purchasable
    

    Structural Results Found: (before additional filtering)

    SQL Query Was

    SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN activity AS ac ON ci.sub_id_fk=ac.sub_id_fk INNER JOIN target AS t ON ac.target_fk=t.target_id  WHERE c.free = 1 AND t.code LIKE 'GLR-1-E' AND t.atype_fk = 0 AND c.purchasable IN (1,2,4,5)    LIMIT 50

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