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    • Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
    UCSF
    ZINC Item Suppliers, Protomers, & Similar Substances

    Analogs

    3072905
    3072905
    8737440
    8737440

    Draw Identity 99% 90% 80% 70%


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    Popular Name:

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    Vendors

    And 9 More

    Activity (Go SEA)

    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    PYGM-3-E Muscle Glycogen Phosphorylase (cluster #3 Of 4), Eukaryotic Eukaryotes 5400 0.37 Binding ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.72 6.55 -6.66 2 4 0 58 268.316 3 ↓

    Analogs

    36889913
    36889913

    Draw Identity 99% 90% 80% 70%

    Popular Name: 1-(4-methoxyphenyl)-3-(3-nitrophenyl)-propane-1,3-dione 1-(4-methoxyphenyl)-3-(3-nitroph…

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    Vendors

    Activity (Go SEA)

    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    PYGM-3-E Muscle Glycogen Phosphorylase (cluster #3 Of 4), Eukaryotic Eukaryotes 4100 0.34 Binding ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 4.06 9.12 -39.17 0 6 -1 95 298.274 5 ↓
    Mid Mid (pH 6-8) 2.87 3.28 -29.1 0 6 0 89 299.282 6 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-benzyl-N'-(2-chlorophenyl)oxamide N-benzyl-N'-(2-chlorophenyl)oxamide

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    Vendors

    And 3 More

    Activity (Go SEA)

    Clustered Target Annotations
    Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
    PYGM-3-E Muscle Glycogen Phosphorylase (cluster #3 Of 4), Eukaryotic Eukaryotes 3000 0.39 Binding ≤ 10μM

    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.25 -1.88 -5.94 2 4 0 58 288.734 4 ↓

    Parameters Provided:

    target.name = PYGM-3-E
target.type = B10
page.format = summary
page.num = 1
filter.purchasability = purchasable

    Structural Results Found: (before additional filtering)

    SQL Query Was

    SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN activity AS ac ON ci.sub_id_fk=ac.sub_id_fk INNER JOIN target AS t ON ac.target_fk=t.target_id  WHERE c.free = 1 AND t.code LIKE 'PYGM-3-E' AND t.atype_fk = 0 AND c.purchasable IN (1,2,4,5)    LIMIT 50

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