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Powers - Lead-like (Public by Lezlyyman) Purchasability Report

ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

21636820
21636820
15672269
15672269
15672271
15672271

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Popular Name: (2R)-N-ethyl-1-[5-(2-oxopyrrolidin-1-yl)-1,3,4-thiadiazol-2-yl]pyrrolidine-2-carboxamide (2R)-N-ethyl-1-[5-(2-oxopyrrolid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.12 3.16 -20.31 1 7 0 78 309.395 4 ↓

Analogs

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Popular Name: 1-(2,5-difluorophenyl)-N-[(2S)-2-hydroxy-2-phenyl-propyl]methanesulfonamide 1-(2,5-difluorophenyl)-N-[(2S)-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.72 3.46 -12.44 2 4 0 66 341.379 6 ↓

Analogs

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Popular Name: (S)-2-amino-2-(4-(2-chlorobenzyloxy)-3-methoxyphenyl)acetic acid (S)-2-amino-2-(4-(2-chlorobenzyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.54 6.99 -40.08 3 5 0 86 321.76 6 ↓

Analogs

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Popular Name: 2-[(5-carbamoyl-3-thienyl)sulfonylamino]benzoic 2-[(5-carbamoyl-3-thienyl)sulfon…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.39 -0.02 -52.92 3 7 -1 129 325.347 5 ↓
Hi High (pH 8-9.5) 1.39 0.07 -123.05 2 7 -2 131 324.339 5 ↓

Analogs

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Popular Name: 5-fluoro-2-[(5-methyl-2-thienyl)sulfonylamino]benzoic 5-fluoro-2-[(5-methyl-2-thienyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.06 4.27 -116.64 0 5 -2 88 313.331 4 ↓
Mid Mid (pH 6-8) 3.06 4.2 -46.9 1 5 -1 86 314.339 4 ↓

Analogs

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Popular Name: 1-benzyl-N-[(3-carbamoylphenyl)methyl]triazole-4-carboxamide 1-benzyl-N-[(3-carbamoylphenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.07 3.56 -17.4 3 7 0 103 335.367 6 ↓

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.79 5.24 -15.35 2 7 0 97 330.34 6 ↓