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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

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Popular Name: 6-[(S)-amino-[(2S)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(S)-amino-[(2S)-tetrahydropyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.45 5.56 -51.93 3 4 1 57 275.372 2 ↓
Hi High (pH 8-9.5) -0.45 5.27 -7.07 2 4 0 56 274.364 2 ↓

Analogs

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Popular Name: 6-[(R)-amino-[(2S)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(R)-amino-[(2S)-tetrahydropyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.45 5.32 -55.63 3 4 1 57 275.372 2 ↓
Hi High (pH 8-9.5) -0.45 5 -7.76 2 4 0 56 274.364 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-[(S)-amino-[(2R)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(S)-amino-[(2R)-tetrahydropyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.45 5.32 -55.92 3 4 1 57 275.372 2 ↓
Hi High (pH 8-9.5) -0.45 5.04 -7.28 2 4 0 56 274.364 2 ↓

Analogs

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Popular Name: 6-[(R)-amino-[(2R)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(R)-amino-[(2R)-tetrahydropyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.45 5.57 -52.09 3 4 1 57 275.372 2 ↓
Hi High (pH 8-9.5) -0.45 5.23 -7.51 2 4 0 56 274.364 2 ↓

Analogs

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Popular Name: 1-methyl-6-[(S)-methylamino-[(2S)-tetrahydropyran-2-yl]methyl]-3,4-dihydroquinolin-2-one 1-methyl-6-[(S)-methylamino-[(2S…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.80 7.23 -46.53 2 4 1 46 289.399 3 ↓
Hi High (pH 8-9.5) 1.80 6.24 -7.08 1 4 0 42 288.391 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 1-methyl-6-[(R)-methylamino-[(2S)-tetrahydropyran-2-yl]methyl]-3,4-dihydroquinolin-2-one 1-methyl-6-[(R)-methylamino-[(2S…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.80 7.01 -49.77 2 4 1 46 289.399 3 ↓
Hi High (pH 8-9.5) 1.80 5.89 -7.41 1 4 0 42 288.391 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 1-methyl-6-[(S)-methylamino-[(2R)-tetrahydropyran-2-yl]methyl]-3,4-dihydroquinolin-2-one 1-methyl-6-[(S)-methylamino-[(2R…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.80 7.01 -50 2 4 1 46 289.399 3 ↓
Hi High (pH 8-9.5) 1.80 5.94 -7.36 1 4 0 42 288.391 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 1-methyl-6-[(R)-methylamino-[(2R)-tetrahydropyran-2-yl]methyl]-3,4-dihydroquinolin-2-one 1-methyl-6-[(R)-methylamino-[(2R…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.80 7.22 -46.33 2 4 1 46 289.399 3 ↓
Hi High (pH 8-9.5) 1.80 6.17 -7.59 1 4 0 42 288.391 3 ↓

Analogs

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Popular Name: 6-[(S)-hydroxy-[(2S)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(S)-hydroxy-[(2S)-tetrahydrop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.25 5.29 -7.92 1 4 0 50 275.348 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-[(R)-hydroxy-[(2S)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(R)-hydroxy-[(2S)-tetrahydrop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.25 4.9 -8.42 1 4 0 50 275.348 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-[(S)-hydroxy-[(2R)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(S)-hydroxy-[(2R)-tetrahydrop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.25 4.86 -8.53 1 4 0 50 275.348 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-[(R)-hydroxy-[(2R)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(R)-hydroxy-[(2R)-tetrahydrop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.25 5.29 -8.04 1 4 0 50 275.348 2 ↓

Analogs

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Popular Name: 6-[(S)-chloro-[(2S)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(S)-chloro-[(2S)-tetrahydropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 8.63 -8.3 0 3 0 30 293.794 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-[(R)-chloro-[(2S)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(R)-chloro-[(2S)-tetrahydropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 8.35 -7.07 0 3 0 30 293.794 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-[(S)-chloro-[(2R)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(S)-chloro-[(2R)-tetrahydropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 8.38 -7.15 0 3 0 30 293.794 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-[(R)-chloro-[(2R)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(R)-chloro-[(2R)-tetrahydropy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 8.63 -8.34 0 3 0 30 293.794 2 ↓

Analogs

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Popular Name: 6-[(S)-bromo-[(2S)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(S)-bromo-[(2S)-tetrahydropyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.75 8.71 -8.04 0 3 0 30 338.245 2 ↓

Analogs

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Popular Name: 6-[(R)-bromo-[(2S)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(R)-bromo-[(2S)-tetrahydropyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.75 8.41 -6.92 0 3 0 30 338.245 2 ↓

Analogs

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Popular Name: 6-[(S)-bromo-[(2R)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(S)-bromo-[(2R)-tetrahydropyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.75 8.46 -6.99 0 3 0 30 338.245 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-[(R)-bromo-[(2R)-tetrahydropyran-2-yl]methyl]-1-methyl-3,4-dihydroquinolin-2-one 6-[(R)-bromo-[(2R)-tetrahydropyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.75 8.71 -8.07 0 3 0 30 338.245 2 ↓

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
page.num = 1

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 275867 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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