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62887251

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-cyclopropyl-3-methyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-3-methyl-pyrr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.65	2.19	-40.08	3	3	1	46	169.248	2	↓ MOL2 SDF SMILES Flexibase

62887253

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-3-methyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-3-methyl-pyrr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.65	2.08	-39.99	3	3	1	46	169.248	2	↓ MOL2 SDF SMILES Flexibase

62887255

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-cyclopropyl-3-ethyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-3-ethyl-pyrro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.98	2.61	-40.68	3	3	1	46	183.275	3	↓ MOL2 SDF SMILES Flexibase

62887257

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-3-ethyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-3-ethyl-pyrro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.98	2.67	-39.5	3	3	1	46	183.275	3	↓ MOL2 SDF SMILES Flexibase

62887259

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-cyclopropyl-3-propyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-3-propyl-pyrr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.54	3.38	-41.04	3	3	1	46	197.302	4	↓ MOL2 SDF SMILES Flexibase

62887261

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-3-propyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-3-propyl-pyrr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.54	3.44	-39.88	3	3	1	46	197.302	4	↓ MOL2 SDF SMILES Flexibase

62890264

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-N-ethyl-3-methyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-N-ethyl-3-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.94	4.06	-40.86	2	3	1	37	197.302	3	↓ MOL2 SDF SMILES Flexibase

62890265

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-cyclopropyl-N-ethyl-3-methyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-N-ethyl-3-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.94	4.08	-41.08	2	3	1	37	197.302	3	↓ MOL2 SDF SMILES Flexibase

62890266

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-cyclopropyl-N,3-diethyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-N,3-diethyl-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.27	4.44	-46.62	2	3	1	37	211.329	4	↓ MOL2 SDF SMILES Flexibase

62890267

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-N,3-diethyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-N,3-diethyl-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.27	4.44	-44.82	2	3	1	37	211.329	4	↓ MOL2 SDF SMILES Flexibase

62890268

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-cyclopropyl-N-ethyl-3-propyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-N-ethyl-3-pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.83	5.25	-46.61	2	3	1	37	225.356	5	↓ MOL2 SDF SMILES Flexibase

62890269

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-N-ethyl-3-propyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-N-ethyl-3-pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.83	5.11	-45.17	2	3	1	37	225.356	5	↓ MOL2 SDF SMILES Flexibase

62890270

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-cyclopropyl-N,3-dimethyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-N,3-dimethyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.56	3.37	-41.44	2	3	1	37	183.275	2	↓ MOL2 SDF SMILES Flexibase

62890271

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-N,3-dimethyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-N,3-dimethyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.56	3.26	-41.21	2	3	1	37	183.275	2	↓ MOL2 SDF SMILES Flexibase

62890272

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-cyclopropyl-3-ethyl-N-methyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-3-ethyl-N-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.90	3.84	-47.98	2	3	1	37	197.302	3	↓ MOL2 SDF SMILES Flexibase

62890273

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-3-ethyl-N-methyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-3-ethyl-N-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.90	3.86	-44.67	2	3	1	37	197.302	3	↓ MOL2 SDF SMILES Flexibase

62890274

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-cyclopropyl-N-methyl-3-propyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-N-methyl-3-pr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.46	4.62	-48.24	2	3	1	37	211.329	4	↓ MOL2 SDF SMILES Flexibase

62890275

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-N-methyl-3-propyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-N-methyl-3-pr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.46	4.62	-44.91	2	3	1	37	211.329	4	↓ MOL2 SDF SMILES Flexibase

62890312

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-3-methyl-N-propyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-3-methyl-N-pr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.44	4.85	-40.81	2	3	1	37	211.329	4	↓ MOL2 SDF SMILES Flexibase

62890313

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-cyclopropyl-3-methyl-N-propyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-3-methyl-N-pr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.44	4.79	-40.84	2	3	1	37	211.329	4	↓ MOL2 SDF SMILES Flexibase

62890314

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-3-ethyl-N-propyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-3-ethyl-N-pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.77	5.34	-44.97	2	3	1	37	225.356	5	↓ MOL2 SDF SMILES Flexibase

62890315

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-cyclopropyl-3-ethyl-N-propyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-3-ethyl-N-pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.77	5.27	-46.18	2	3	1	37	225.356	5	↓ MOL2 SDF SMILES Flexibase

62890316

Analogs

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Popular Name: (3S)-N-cyclopropyl-N,3-dipropyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-N,3-dipropyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.33	6.11	-46.79	2	3	1	37	239.383	6	↓ MOL2 SDF SMILES Flexibase

62890317

Analogs

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Popular Name: (3R)-N-cyclopropyl-N,3-dipropyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-N,3-dipropyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.33	6.17	-44.42	2	3	1	37	239.383	6	↓ MOL2 SDF SMILES Flexibase

62891144

Analogs

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Popular Name: (3S)-N-cyclopropyl-N-(2-hydroxyethyl)-3-methyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-N-(2-hydroxye…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.07	1.15	-41.01	3	4	1	57	213.301	4	↓ MOL2 SDF SMILES Flexibase

62891145

Analogs

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Popular Name: (3R)-N-cyclopropyl-N-(2-hydroxyethyl)-3-methyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-N-(2-hydroxye…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.07	1.09	-44.92	3	4	1	57	213.301	4	↓ MOL2 SDF SMILES Flexibase

62891146

Analogs

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Popular Name: (3S)-N-cyclopropyl-3-ethyl-N-(2-hydroxyethyl)pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-3-ethyl-N-(2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.26	1.65	-46.03	3	4	1	57	227.328	5	↓ MOL2 SDF SMILES Flexibase

62891147

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-3-ethyl-N-(2-hydroxyethyl)pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-3-ethyl-N-(2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.26	1.66	-43.44	3	4	1	57	227.328	5	↓ MOL2 SDF SMILES Flexibase

62891148

Analogs

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Popular Name: (3S)-N-cyclopropyl-N-(2-hydroxyethyl)-3-propyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-N-(2-hydroxye…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.82	2.41	-45.84	3	4	1	57	241.355	6	↓ MOL2 SDF SMILES Flexibase

62891149

Analogs

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Popular Name: (3R)-N-cyclopropyl-N-(2-hydroxyethyl)-3-propyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-N-(2-hydroxye…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.82	2.42	-43.64	3	4	1	57	241.355	6	↓ MOL2 SDF SMILES Flexibase

62895083

Analogs

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Popular Name: (3R)-N-cyclopropyl-N-isobutyl-3-methyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-N-isobutyl-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.68	6.14	-40.23	2	3	1	37	225.356	4	↓ MOL2 SDF SMILES Flexibase

62895084

Analogs

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Popular Name: (3S)-N-cyclopropyl-N-isobutyl-3-methyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-N-isobutyl-3-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.68	5.76	-41.74	2	3	1	37	225.356	4	↓ MOL2 SDF SMILES Flexibase

62895101

Analogs

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Popular Name: (3R)-N-cyclopropyl-N-isopentyl-3-methyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-N-isopentyl-3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.21	6.12	-40.69	2	3	1	37	239.383	5	↓ MOL2 SDF SMILES Flexibase

62895102

Analogs

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Popular Name: (3S)-N-cyclopropyl-N-isopentyl-3-methyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-N-isopentyl-3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.21	6.15	-40.71	2	3	1	37	239.383	5	↓ MOL2 SDF SMILES Flexibase

62895103

Analogs

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Popular Name: (3S)-N-cyclopropyl-3-ethyl-N-isopentyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-3-ethyl-N-iso…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.55	6.67	-46.66	2	3	1	37	253.41	6	↓ MOL2 SDF SMILES Flexibase

62895104

Analogs

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Popular Name: (3R)-N-cyclopropyl-3-ethyl-N-isopentyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-3-ethyl-N-iso…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.55	6.68	-43.98	2	3	1	37	253.41	6	↓ MOL2 SDF SMILES Flexibase

62895105

Analogs

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Popular Name: (3S)-N-cyclopropyl-N-isopentyl-3-propyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-N-isopentyl-3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.11	7.4	-46.62	2	3	1	37	267.437	7	↓ MOL2 SDF SMILES Flexibase

62895106

Analogs

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Popular Name: (3R)-N-cyclopropyl-N-isopentyl-3-propyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-N-isopentyl-3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.11	7.45	-44.44	2	3	1	37	267.437	7	↓ MOL2 SDF SMILES Flexibase

62895347

Analogs

43448414
43448415

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Popular Name: (3R)-N-butyl-N-cyclopropyl-3-methyl-pyrrolidine-3-carboxamide (3R)-N-butyl-N-cyclopropyl-3-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.00	5.63	-40.74	2	3	1	37	225.356	5	↓ MOL2 SDF SMILES Flexibase

62895348

Analogs

43448414
43448415

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Popular Name: (3S)-N-butyl-N-cyclopropyl-3-methyl-pyrrolidine-3-carboxamide (3S)-N-butyl-N-cyclopropyl-3-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.00	5.64	-40.72	2	3	1	37	225.356	5	↓ MOL2 SDF SMILES Flexibase

62895351

Analogs

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Popular Name: (3R)-N-butyl-N-cyclopropyl-3-propyl-pyrrolidine-3-carboxamide (3R)-N-butyl-N-cyclopropyl-3-pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.89	6.9	-45.21	2	3	1	37	253.41	7	↓ MOL2 SDF SMILES Flexibase

62895352

Analogs

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Popular Name: (3S)-N-butyl-N-cyclopropyl-3-propyl-pyrrolidine-3-carboxamide (3S)-N-butyl-N-cyclopropyl-3-pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.89	6.82	-46.34	2	3	1	37	253.41	7	↓ MOL2 SDF SMILES Flexibase

62895657

Analogs

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Popular Name: (3S)-N-cyclopropyl-N-(2-methoxyethyl)-3-methyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-N-(2-methoxye…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.55	3.56	-40.24	2	4	1	46	227.328	5	↓ MOL2 SDF SMILES Flexibase

62895658

Analogs

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Popular Name: (3R)-N-cyclopropyl-N-(2-methoxyethyl)-3-methyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-N-(2-methoxye…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.55	3.49	-43.97	2	4	1	46	227.328	5	↓ MOL2 SDF SMILES Flexibase

62895659

Analogs

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Popular Name: (3S)-N-cyclopropyl-3-ethyl-N-(2-methoxyethyl)pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-3-ethyl-N-(2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.88	4.06	-45.8	2	4	1	46	241.355	6	↓ MOL2 SDF SMILES Flexibase

62895660

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-3-ethyl-N-(2-methoxyethyl)pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-3-ethyl-N-(2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.88	4.06	-42.59	2	4	1	46	241.355	6	↓ MOL2 SDF SMILES Flexibase

62895661

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3S)-N-cyclopropyl-N-(2-methoxyethyl)-3-propyl-pyrrolidine-3-carboxamide (3S)-N-cyclopropyl-N-(2-methoxye…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.44	4.85	-46.16	2	4	1	46	255.382	7	↓ MOL2 SDF SMILES Flexibase

62895662

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3R)-N-cyclopropyl-N-(2-methoxyethyl)-3-propyl-pyrrolidine-3-carboxamide (3R)-N-cyclopropyl-N-(2-methoxye…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.44	4.82	-42.76	2	4	1	46	255.382	7	↓ MOL2 SDF SMILES Flexibase

62896409

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.80	5.26	-46.16	2	5	1	63	255.338	6	↓ MOL2 SDF SMILES Flexibase

62896410

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: ethyl ethyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.80	5.35	-45.34	2	5	1	63	255.338	6	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

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<script type="text/javascript" src="//zinc12.docking.org/js/embed.js"></script>
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