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Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-6-hydrazino-pyridazine-3-carboxamide N-[(1S)-1-cyclopentylethyl]-6-hy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.15 2.99 -9.37 4 6 0 93 249.318 4 ↓
Lo Low (pH 4.5-6) 1.15 3.22 -32.07 5 6 1 94 250.326 4 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-6-hydrazino-pyridazine-3-carboxamide N-[(1R)-1-cyclopentylethyl]-6-hy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.15 2.77 -9.35 4 6 0 93 249.318 4 ↓
Lo Low (pH 4.5-6) 1.15 3 -32.24 5 6 1 94 250.326 4 ↓

Analogs

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Popular Name: 6-chloro-N-[(1S)-1-cyclopentylethyl]pyridazine-3-carboxamide 6-chloro-N-[(1S)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.58 4.78 -5.85 1 4 0 55 253.733 3 ↓

Analogs

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Popular Name: 6-chloro-N-[(1R)-1-cyclopentylethyl]pyridazine-3-carboxamide 6-chloro-N-[(1R)-1-cyclopentylet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.58 4.56 -5.79 1 4 0 55 253.733 3 ↓

Analogs

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Popular Name: 6-amino-N-[(1S)-1-cyclopentylethyl]pyridazine-3-carboxamide 6-amino-N-[(1S)-1-cyclopentyleth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.39 3.29 -34.55 4 5 1 82 235.311 3 ↓
Mid Mid (pH 6-8) 1.39 3.13 -8.4 3 5 0 81 234.303 3 ↓
Lo Low (pH 4.5-6) 1.39 3.36 -31.79 4 5 1 82 235.311 3 ↓

Analogs

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Popular Name: 6-amino-N-[(1R)-1-cyclopentylethyl]pyridazine-3-carboxamide 6-amino-N-[(1R)-1-cyclopentyleth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.39 3.07 -34.62 4 5 1 82 235.311 3 ↓
Mid Mid (pH 6-8) 1.39 2.91 -8.36 3 5 0 81 234.303 3 ↓
Lo Low (pH 4.5-6) 1.39 3.14 -31.99 4 5 1 82 235.311 3 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-6-(propylamino)pyridazine-3-carboxamide N-[(1S)-1-cyclopentylethyl]-6-(p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.64 5.77 -31.69 3 5 1 68 277.392 6 ↓
Mid Mid (pH 6-8) 2.64 5.61 -7.12 2 5 0 67 276.384 6 ↓
Lo Low (pH 4.5-6) 2.64 5.84 -29.94 3 5 1 68 277.392 6 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-6-(propylamino)pyridazine-3-carboxamide N-[(1R)-1-cyclopentylethyl]-6-(p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.64 5.55 -31.79 3 5 1 68 277.392 6 ↓
Mid Mid (pH 6-8) 2.64 5.39 -7.09 2 5 0 67 276.384 6 ↓
Lo Low (pH 4.5-6) 2.64 5.62 -30.17 3 5 1 68 277.392 6 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-6-(ethylamino)pyridazine-3-carboxamide N-[(1S)-1-cyclopentylethyl]-6-(e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.14 5.02 -31.41 3 5 1 68 263.365 5 ↓
Mid Mid (pH 6-8) 2.14 4.85 -7.51 2 5 0 67 262.357 5 ↓
Lo Low (pH 4.5-6) 2.14 5.08 -29.85 3 5 1 68 263.365 5 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-6-(ethylamino)pyridazine-3-carboxamide N-[(1R)-1-cyclopentylethyl]-6-(e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.14 4.8 -31.51 3 5 1 68 263.365 5 ↓
Mid Mid (pH 6-8) 2.14 4.63 -7.5 2 5 0 67 262.357 5 ↓
Lo Low (pH 4.5-6) 2.14 4.86 -30.02 3 5 1 68 263.365 5 ↓

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-6-(methylamino)pyridazine-3-carboxamide N-[(1S)-1-cyclopentylethyl]-6-(m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.76 4.21 -31.97 3 5 1 68 249.338 4 ↓
Mid Mid (pH 6-8) 1.76 4.04 -8.08 2 5 0 67 248.33 4 ↓
Lo Low (pH 4.5-6) 1.76 4.27 -30.13 3 5 1 68 249.338 4 ↓

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-6-(methylamino)pyridazine-3-carboxamide N-[(1R)-1-cyclopentylethyl]-6-(m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.76 3.98 -32.08 3 5 1 68 249.338 4 ↓
Mid Mid (pH 6-8) 1.76 3.82 -8.01 2 5 0 67 248.33 4 ↓
Lo Low (pH 4.5-6) 1.76 4.05 -30.26 3 5 1 68 249.338 4 ↓

Analogs

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Popular Name: N-[(1-hydroxycyclopentyl)methyl]-6-oxo-1H-pyridazine-3-carboxamide N-[(1-hydroxycyclopentyl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.41 -3.05 -39.72 2 6 -1 98 236.251 3 ↓
Lo Low (pH 4.5-6) -0.05 -1.19 -9.07 3 6 0 95 237.259 3 ↓

Parameters Provided:

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 476716 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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