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Analogs

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Popular Name: 6-methyl-N-[(2,4,6-trimethoxyphenyl)methyl]imidazo[2,1-b][1,3,4]thiadiazol-2-amine 6-methyl-N-[(2,4,6-trimethoxyphe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.33 5.17 -11.62 1 7 0 70 334.401 6 ↓
Mid Mid (pH 6-8) 2.33 5.66 -26.29 2 7 1 71 335.409 6 ↓

Analogs

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Popular Name: 6-tert-butyl-N-[(1S)-1-(3-nitrophenyl)ethyl]imidazo[2,1-b][1,3,4]thiadiazol-2-amine 6-tert-butyl-N-[(1S)-1-(3-nitrop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.52 10.52 -14.71 1 7 0 88 345.428 5 ↓
Lo Low (pH 4.5-6) 4.52 11.02 -33.37 2 7 1 89 346.436 5 ↓

Analogs

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Popular Name: 6-tert-butyl-N-[(1R)-1-(3-nitrophenyl)ethyl]imidazo[2,1-b][1,3,4]thiadiazol-2-amine 6-tert-butyl-N-[(1R)-1-(3-nitrop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.52 10.52 -14.72 1 7 0 88 345.428 5 ↓
Lo Low (pH 4.5-6) 4.52 11.02 -33.33 2 7 1 89 346.436 5 ↓

Analogs

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Popular Name: 4-[(1S)-1-[(6-tert-butylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)amino]ethyl]-N,N-dimethyl-benzenesulfon 4-[(1S)-1-[(6-tert-butylimidazo[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.90 7.81 -15.75 1 7 0 80 407.565 6 ↓
Lo Low (pH 4.5-6) 3.90 8.31 -33.64 2 7 1 81 408.573 6 ↓

Analogs

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Popular Name: 4-[(1R)-1-[(6-tert-butylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)amino]ethyl]-N,N-dimethyl-benzenesulfon 4-[(1R)-1-[(6-tert-butylimidazo[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.90 7.81 -16.2 1 7 0 80 407.565 6 ↓
Lo Low (pH 4.5-6) 3.90 8.31 -32.9 2 7 1 81 408.573 6 ↓

Analogs

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Popular Name: N-[(1S)-1-(3-chloro-4-fluoro-phenyl)ethyl]-6-methyl-imidazo[2,1-b][1,3,4]thiadiazol-2-amine N-[(1S)-1-(3-chloro-4-fluoro-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.63 8.47 -11.86 1 4 0 42 310.785 3 ↓
Mid Mid (pH 6-8) 3.63 8.98 -30.72 2 4 1 43 311.793 3 ↓

Analogs

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Popular Name: N-[(1R)-1-(3-chloro-4-fluoro-phenyl)ethyl]-6-methyl-imidazo[2,1-b][1,3,4]thiadiazol-2-amine N-[(1R)-1-(3-chloro-4-fluoro-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.63 8.47 -11.83 1 4 0 42 310.785 3 ↓
Mid Mid (pH 6-8) 3.63 8.98 -30.73 2 4 1 43 311.793 3 ↓

Analogs

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Popular Name: 6-methyl-N-[(4-methylsulfanylphenyl)methyl]imidazo[2,1-b][1,3,4]thiadiazol-2-amine 6-methyl-N-[(4-methylsulfanylphe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.73 8.17 -10.9 1 4 0 42 290.417 4 ↓
Mid Mid (pH 6-8) 2.73 8.65 -27.7 2 4 1 43 291.425 4 ↓

Analogs

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Popular Name: N-[(4-bromo-2-chloro-phenyl)methyl]-6-methyl-imidazo[2,1-b][1,3,4]thiadiazol-2-amine N-[(4-bromo-2-chloro-phenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.72 8.18 -10.3 1 4 0 42 357.664 3 ↓
Mid Mid (pH 6-8) 3.72 8.66 -26.98 2 4 1 43 358.672 3 ↓

Analogs

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Popular Name: 2-methoxy-4-[[(6-methylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)amino]methyl]phenol 2-methoxy-4-[[(6-methylimidazo[2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.64 4.27 -13.4 2 6 0 72 290.348 4 ↓
Mid Mid (pH 6-8) 1.64 4.76 -31.04 3 6 1 73 291.356 4 ↓

Analogs

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Popular Name: 2-methoxy-5-[[(6-methylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)amino]methyl]phenol 2-methoxy-5-[[(6-methylimidazo[2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.64 4.28 -13.5 2 6 0 72 290.348 4 ↓
Mid Mid (pH 6-8) 1.64 4.77 -30.55 3 6 1 73 291.356 4 ↓

Analogs

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Popular Name: N-[(2-bromo-5-methoxy-phenyl)methyl]-6-methyl-imidazo[2,1-b][1,3,4]thiadiazol-2-amine N-[(2-bromo-5-methoxy-phenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 7 -10.28 1 5 0 51 353.245 4 ↓
Mid Mid (pH 6-8) 3.09 7.5 -25.7 2 5 1 53 354.253 4 ↓

Analogs

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Popular Name: N-[(3-methoxy-4-methyl-phenyl)methyl]-6-methyl-imidazo[2,1-b][1,3,4]thiadiazol-2-amine N-[(3-methoxy-4-methyl-phenyl)me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.73 7.19 -10.9 1 5 0 51 288.376 4 ↓
Mid Mid (pH 6-8) 2.73 7.68 -27.82 2 5 1 53 289.384 4 ↓

Analogs

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Popular Name: 6-methyl-N-[(3-nitrophenyl)methyl]imidazo[2,1-b][1,3,4]thiadiazol-2-amine 6-methyl-N-[(3-nitrophenyl)methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.24 7.86 -16.27 1 7 0 88 289.32 4 ↓
Mid Mid (pH 6-8) 2.24 8.36 -34.32 2 7 1 89 290.328 4 ↓

Analogs

42099537
42099537

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Popular Name: N-[(1S)-1-(2,5-difluorophenyl)ethyl]-6-methyl-imidazo[2,1-b][1,3,4]thiadiazol-2-amine N-[(1S)-1-(2,5-difluorophenyl)et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.11 8.24 -10.66 1 4 0 42 294.33 3 ↓
Mid Mid (pH 6-8) 3.11 8.76 -27.52 2 4 1 43 295.338 3 ↓

Analogs

42099536
42099536

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Popular Name: N-[(1R)-1-(2,5-difluorophenyl)ethyl]-6-methyl-imidazo[2,1-b][1,3,4]thiadiazol-2-amine N-[(1R)-1-(2,5-difluorophenyl)et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.11 8.04 -9.76 1 4 0 42 294.33 3 ↓
Mid Mid (pH 6-8) 3.11 8.55 -26.94 2 4 1 43 295.338 3 ↓

Analogs

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Popular Name: N-[(5-bromo-2-fluoro-phenyl)methyl]-6-methyl-imidazo[2,1-b][1,3,4]thiadiazol-2-amine N-[(5-bromo-2-fluoro-phenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.20 7.78 -9.93 1 4 0 42 341.209 3 ↓
Mid Mid (pH 6-8) 3.20 8.27 -26.05 2 4 1 43 342.217 3 ↓

Analogs

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Popular Name: 3-[[(6-methylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)amino]methyl]benzonitrile 3-[[(6-methylimidazo[2,1-b][1,3,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.03 7.53 -14.66 1 5 0 66 269.333 3 ↓
Mid Mid (pH 6-8) 2.03 8.01 -31.98 2 5 1 67 270.341 3 ↓

Parameters Provided:

ring.id = 85872
filter.purchasability = annotated
page.format = targets
page.num = 1

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 85872 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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