UCSF

3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type I, Human (387 Compounds)

Swissprot:
3BHS1_HUMAN
Stitch:
3BHS1_HUMAN
UniProt:
P14060
ChEMBL:
CHEMBL1958
Reactome:
REACT_11059
REACT_11036
REACT_11047
PDB:
HSD3B1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 387 5 1 1
Binding ≤ 1μM 321 5 1 1

Reactome Network (3)

Reactome ID Description Species
REACT_11059 Androgen biosynthesis Homo sapiens
REACT_11036 Glucocorticoid biosynthesis Homo sapiens
REACT_11047 Mineralocorticoid biosynthesis Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
3BHS2_HUMAN P26439 CHEMBL3670 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Human 369
S5A1_HUMAN P18405 CHEMBL1787 Steroid 5-alpha-reductase 1, Human 369
S5A2_HUMAN P31213 CHEMBL1856 Steroid 5-alpha-reductase 2, Human 379

Glucocorticoid biosynthesis

Uniprot Swissprot Chembl Description Number Shared
3BHS2_HUMAN P26439 CHEMBL3670 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Human 369

Mineralocorticoid biosynthesis

Uniprot Swissprot Chembl Description Number Shared
3BHS2_HUMAN P26439 CHEMBL3670 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Human 369
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
3BHS2_HUMAN P26439 CHEMBL3670 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Human 370 5 1 1
3BHS7_HUMAN Q9H2F3 CHEMBL3600 3-beta-hydroxysteroid Dehydrogenase Type VII, Human 116 3 1 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
3BHS1-1-E 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type I (cluster #1 Of 2), Eukaryotic 1 0 0 0
3BHS1-2-E 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type I (cluster #2 Of 2), Eukaryotic 388 5 1 1
Uniprot Swissprot Chembl Description Number Shared
S5A2_HUMAN P31213 CHEMBL1856 Steroid 5-alpha-reductase 2, Human 379
3BHS2_HUMAN P26439 CHEMBL3670 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Human 369
S5A1_HUMAN P18405 CHEMBL1787 Steroid 5-alpha-reductase 1, Human 369
3BHS7_HUMAN Q9H2F3 CHEMBL3600 3-beta-hydroxysteroid Dehydrogenase Type VII, Human 116
S5A1_RAT P24008 CHEMBL3422 Steroid 5-alpha-reductase 1, Rat 20
S5A2_RAT P31214 CHEMBL5099 Steroid 5-alpha-reductase 2, Rat 20
3BHS2_RAT P22072 CHEMBL4821 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Rat 12
3BHS5_RAT P27364 CHEMBL4490 3-beta-hydroxysteroid Dehydrogenase Type III, Rat 12

Most Common Rings