UCSF

Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human (24 Compounds)

Swissprot:
ACHA2_HUMAN
Stitch:
ACHA2_HUMAN
UniProt:
Q15822
ChEMBL:
CHEMBL1794
Reactome:
REACT_22352
REACT_22303
PDB:
CHRNA2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 24 6 4 4
Binding ≤ 1μM 17 4 2 2

Reactome Network (2)

Reactome ID Description Species
REACT_22352 Highly calcium permeable nicotinic acetylcholine receptors Homo sapiens
REACT_22303 Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ACHA3_HUMAN P32297 CHEMBL3068 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human 22
ACHA4_HUMAN P43681 CHEMBL1882 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human 17
ACHA5_HUMAN P30532 CHEMBL2454 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human 5
ACHA6_HUMAN Q15825 CHEMBL2356 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human 5
ACHA_HUMAN P02708 CHEMBL4808 Acetylcholine Receptor Protein Alpha Chain, Human 5
ACHB2_HUMAN P17787 CHEMBL1883 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human 21
ACHB3_HUMAN Q05901 CHEMBL2586 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human 6
ACHB4_HUMAN P30926 CHEMBL3002 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human 23

Highly calcium permeable postsynaptic nicotinic acetylcholine receptors

Uniprot Swissprot Chembl Description Number Shared
ACHA3_HUMAN P32297 CHEMBL3068 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human 22
ACHA4_HUMAN P43681 CHEMBL1882 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human 17
ACHA5_HUMAN P30532 CHEMBL2454 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human 5
ACHA6_HUMAN Q15825 CHEMBL2356 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human 5
ACHA7_HUMAN P36544 CHEMBL2492 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human 8
ACHA9_HUMAN Q9UGM1 CHEMBL2184 Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Human 1
ACHA_HUMAN P02708 CHEMBL4808 Acetylcholine Receptor Protein Alpha Chain, Human 5
ACHB2_HUMAN P17787 CHEMBL1883 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human 21
ACHB3_HUMAN Q05901 CHEMBL2586 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human 6
ACHB4_HUMAN P30926 CHEMBL3002 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human 23
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ACHA2_RAT P12389 CHEMBL2584 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat 307 54 16 4
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ACHA3_HUMAN P32297 CHEMBL3068 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human 84 15 7 7
ACHA4_HUMAN P43681 CHEMBL1882 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human 140 21 4 4
ACHA5_HUMAN P30532 CHEMBL2454 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human 5 3 1 0
ACHA6_HUMAN Q15825 CHEMBL2356 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human 5 3 1 0
ACHA7_HUMAN P36544 CHEMBL2492 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human 142 31 15 10
ACHA9_HUMAN Q9UGM1 CHEMBL2184 Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Human 1 1 0 0
ACHA_HUMAN P02708 CHEMBL4808 Acetylcholine Receptor Protein Alpha Chain, Human 8 3 1 0

Clustered By Gene (0)

Clustered By Organism (5)

Code Description Substances Purchasable Natural In Man
ACHA2-1-E Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit (cluster #1 Of 6), Eukaryotic 71 14 1 0
ACHA2-2-E Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit (cluster #2 Of 6), Eukaryotic 91 8 0 1
ACHA2-3-E Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit (cluster #3 Of 6), Eukaryotic 2 2 2 2
ACHA2-4-E Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit (cluster #4 Of 6), Eukaryotic 113 25 5 2
ACHA2-5-E Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit (cluster #5 Of 6), Eukaryotic 43 5 7 2
ACHA2-6-E Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit (cluster #6 Of 6), Eukaryotic 8 3 3 0
Uniprot Swissprot Chembl Description Number Shared
ACHB4_HUMAN P30926 CHEMBL3002 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human 23
ACHA3_HUMAN P32297 CHEMBL3068 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human 22
ACHB2_HUMAN P17787 CHEMBL1883 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human 21
ACHA4_HUMAN P43681 CHEMBL1882 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human 17
ACHB4_RAT P12392 CHEMBL2658 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat 17
Z104290 Z104290 CHEMBL1907596 Neuronal Acetylcholine Receptor; Alpha4/beta2 16
ACHB2_RAT P12390 CHEMBL3001 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Rat 14
ACHD_TORCA P02718 CHEMBL3916 Acetylcholine Receptor Protein Delta Chain, Torca 10
Z104283 Z104283 CHEMBL1907589 Neuronal Acetylcholine Receptor; Alpha4/beta2 10
Z104288 Z104288 CHEMBL1907594 Neuronal Acetylcholine Receptor; Alpha3/beta4 9
Z104287 Z104287 CHEMBL1907593 Neuronal Acetylcholine Receptor; Alpha3/beta4 8
ACHA7_HUMAN P36544 CHEMBL2492 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human 7
ACHA7_RAT Q05941 CHEMBL4980 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat 6
Z104285 Z104285 CHEMBL1907591 Neuronal Acetylcholine Receptor; Alpha4/beta4 6
ACH10_HUMAN Q9GZZ6 CHEMBL2551 Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Human 5
ACHA5_HUMAN P30532 CHEMBL2454 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human 5
ACHA6_HUMAN Q15825 CHEMBL2356 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human 5
ACHA_HUMAN P02708 CHEMBL4808 Acetylcholine Receptor Protein Alpha Chain, Human 5
ACHB3_HUMAN Q05901 CHEMBL2586 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human 5
ACHD_HUMAN Q07001 CHEMBL3011 Acetylcholine Receptor Protein Delta Chain, Human 5
ACHA2_RAT P12389 CHEMBL2584 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat 4
ACHA3_RAT P04757 CHEMBL3818 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Rat 4
ACHA4_RAT P09483 CHEMBL307 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Rat 4
ACHA_TORCA P02710 CHEMBL3097 Acetylcholine Receptor Protein Alpha Chain, Torca 4
ACHB_HUMAN P11230 CHEMBL3355 Acetylcholine Receptor Protein Beta Chain, Human 4
ACHB_TORCA P02712 CHEMBL3803 Acetylcholine Receptor Protein Beta Chain, Torca 4
ACHE_HUMAN Q04844 CHEMBL2484 Acetylcholine Receptor Protein Epsilon Chain, Human 4
ACHG_HUMAN P07510 CHEMBL2613 Acetylcholine Receptor Protein Gamma Chain, Human 4
ACHG_TORCA P02714 CHEMBL4019 Acetylcholine Receptor Protein Gamma Chain, Torca 4
ACH10_RAT Q9JLB5 CHEMBL3461 Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Rat 3
ACHA4_MOUSE O70174 CHEMBL4457 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Mouse 3
ACHA5_RAT P20420 CHEMBL4960 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Rat 3
ACHA6_RAT P43143 CHEMBL4747 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Rat 3
ACHA9_RAT P43144 CHEMBL2585 Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Rat 3
ACHA_RAT P25108 CHEMBL3599 Acetylcholine Receptor Protein Alpha Chain, Rat 3
ACHB3_RAT P12391 CHEMBL4568 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat 3
ACHB_RAT P25109 CHEMBL2666 Acetylcholine Receptor Protein Beta Chain, Rat 3
Q8BGP7_MOUSE Q8BGP7 CHEMBL2235 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Mouse 3
Z104281 Z104281 CHEMBL1907587 Neuronal Acetylcholine Receptor; Alpha3/beta2 3
Z104284 Z104284 CHEMBL1907590 Neuronal Acetylcholine Receptor; Alpha2/beta4 3
Z104286 Z104286 CHEMBL1907592 Neuronal Acetylcholine Receptor; Alpha2/beta2 3
Z104289 Z104289 CHEMBL1907595 Neuronal Acetylcholine Receptor; Alpha4/beta4 3
ACHA7_MOUSE P49582 CHEMBL3365 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Mouse 1
ACHA9_HUMAN Q9UGM1 CHEMBL2184 Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Human 1
ACHP_LYMST P58154 CHEMBL6084 Acetylcholine-binding Protein, Lymst 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
Z104282 Z104282 CHEMBL1907588 Acetylcholine Receptor; Alpha1/beta1/delta/gamma 1
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 1
Z50594 Z50594 CHEMBL375 Mus Musculus 1