UCSF

Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat (307 Compounds)

Swissprot:
ACHA2_RAT
Stitch:
ACHA2_RAT
UniProt:
P12389
ChEMBL:
CHEMBL2584
Reactome:
REACT_196479
PDB:
Chrna2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 307 54 16 4
Binding ≤ 1μM 248 45 12 4

Reactome Network (1)

Reactome ID Description Species
REACT_196479 Highly calcium permeable nicotinic acetylcholine receptors Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
ACHA_RAT P25108 CHEMBL3599 Acetylcholine Receptor Protein Alpha Chain, Rat 296
ACHB2_RAT P12390 CHEMBL3001 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Rat 300
ACHB3_RAT P12391 CHEMBL4568 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat 296
ACHB4_RAT P12392 CHEMBL2658 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat 300
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ACHA2_HUMAN Q15822 CHEMBL1794 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human 24 6 4 4
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ACHA3_RAT P04757 CHEMBL3818 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Rat 367 65 21 9
ACHA4_RAT P09483 CHEMBL307 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Rat 472 78 25 10
ACHA5_RAT P20420 CHEMBL4960 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Rat 296 50 13 2
ACHA6_RAT P43143 CHEMBL4747 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Rat 297 50 13 2
ACHA7_RAT Q05941 CHEMBL4980 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat 828 86 20 12
ACHA9_RAT P43144 CHEMBL2585 Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Rat 300 51 14 3
ACHA_RAT P25108 CHEMBL3599 Acetylcholine Receptor Protein Alpha Chain, Rat 296 50 13 2

Clustered By Gene (0)

Clustered By Organism (5)

Code Description Substances Purchasable Natural In Man
ACHA2-1-E Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit (cluster #1 Of 6), Eukaryotic 71 14 1 0
ACHA2-2-E Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit (cluster #2 Of 6), Eukaryotic 91 8 0 1
ACHA2-3-E Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit (cluster #3 Of 6), Eukaryotic 2 2 2 2
ACHA2-4-E Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit (cluster #4 Of 6), Eukaryotic 113 25 5 2
ACHA2-5-E Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit (cluster #5 Of 6), Eukaryotic 43 5 7 2
ACHA2-6-E Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit (cluster #6 Of 6), Eukaryotic 8 3 3 0
Uniprot Swissprot Chembl Description Number Shared
ACHA3_RAT P04757 CHEMBL3818 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Rat 304
ACHA4_RAT P09483 CHEMBL307 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Rat 304
ACHB2_RAT P12390 CHEMBL3001 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Rat 300
ACHB4_RAT P12392 CHEMBL2658 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat 300
ACHA7_RAT Q05941 CHEMBL4980 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat 298
ACHA6_RAT P43143 CHEMBL4747 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Rat 297
ACH10_RAT Q9JLB5 CHEMBL3461 Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Rat 296
ACHA5_RAT P20420 CHEMBL4960 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Rat 296
ACHA9_RAT P43144 CHEMBL2585 Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Rat 296
ACHA_RAT P25108 CHEMBL3599 Acetylcholine Receptor Protein Alpha Chain, Rat 296
ACHB3_RAT P12391 CHEMBL4568 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat 296
ACHB_RAT P25109 CHEMBL2666 Acetylcholine Receptor Protein Beta Chain, Rat 296
Z104290 Z104290 CHEMBL1907596 Neuronal Acetylcholine Receptor; Alpha4/beta2 36
ACHD_TORCA P02718 CHEMBL3916 Acetylcholine Receptor Protein Delta Chain, Torca 29
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 26
Z104283 Z104283 CHEMBL1907589 Neuronal Acetylcholine Receptor; Alpha4/beta2 15
ACHA3_HUMAN P32297 CHEMBL3068 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human 13
ACHB2_HUMAN P17787 CHEMBL1883 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human 13
ACHA7_HUMAN P36544 CHEMBL2492 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human 10
Z104281 Z104281 CHEMBL1907587 Neuronal Acetylcholine Receptor; Alpha3/beta2 10
Z104287 Z104287 CHEMBL1907593 Neuronal Acetylcholine Receptor; Alpha3/beta4 10
ACHA_TORCA P02710 CHEMBL3097 Acetylcholine Receptor Protein Alpha Chain, Torca 9
Z104286 Z104286 CHEMBL1907592 Neuronal Acetylcholine Receptor; Alpha2/beta2 9
Z104289 Z104289 CHEMBL1907595 Neuronal Acetylcholine Receptor; Alpha4/beta4 9
ACHB_TORCA P02712 CHEMBL3803 Acetylcholine Receptor Protein Beta Chain, Torca 8
ACHG_TORCA P02714 CHEMBL4019 Acetylcholine Receptor Protein Gamma Chain, Torca 8
ACHA4_HUMAN P43681 CHEMBL1882 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human 6
ACHA4_MOUSE O70174 CHEMBL4457 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Mouse 5
Q8BGP7_MOUSE Q8BGP7 CHEMBL2235 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Mouse 5
ACHA2_HUMAN Q15822 CHEMBL1794 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human 4
ACHB4_HUMAN P30926 CHEMBL3002 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human 4
ACHD_HUMAN Q07001 CHEMBL3011 Acetylcholine Receptor Protein Delta Chain, Human 4
VMAT2_RAT Q01827 CHEMBL4828 Synaptic Vesicular Amine Transporter, Rat 4
Z104284 Z104284 CHEMBL1907590 Neuronal Acetylcholine Receptor; Alpha2/beta4 4
Z104288 Z104288 CHEMBL1907594 Neuronal Acetylcholine Receptor; Alpha3/beta4 4
ACH10_HUMAN Q9GZZ6 CHEMBL2551 Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Human 3
ACHA5_HUMAN P30532 CHEMBL2454 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human 3
ACHA6_HUMAN Q15825 CHEMBL2356 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human 3
ACHA_HUMAN P02708 CHEMBL4808 Acetylcholine Receptor Protein Alpha Chain, Human 3
ACHB3_HUMAN Q05901 CHEMBL2586 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human 3
ACHP_LYMST P58154 CHEMBL6084 Acetylcholine-binding Protein, Lymst 3
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 3
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 3
Z104285 Z104285 CHEMBL1907591 Neuronal Acetylcholine Receptor; Alpha4/beta4 3
ACHB_HUMAN P11230 CHEMBL3355 Acetylcholine Receptor Protein Beta Chain, Human 2
ACHE_HUMAN Q04844 CHEMBL2484 Acetylcholine Receptor Protein Epsilon Chain, Human 2
ACHG_HUMAN P07510 CHEMBL2613 Acetylcholine Receptor Protein Gamma Chain, Human 2
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 2
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 2
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 2
VMAT2_HUMAN Q05940 CHEMBL1893 Synaptic Vesicular Amine Transporter, Human 2
Z104282 Z104282 CHEMBL1907588 Acetylcholine Receptor; Alpha1/beta1/delta/gamma 2
ACES_MOUSE P21836 CHEMBL3198 Acetylcholinesterase, Mouse 1
ACHA7_MOUSE P49582 CHEMBL3365 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Mouse 1
ACHA9_HUMAN Q9UGM1 CHEMBL2184 Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Human 1
ACM1_MOUSE P12657 CHEMBL3733 Muscarinic Acetylcholine Receptor M1, Mouse 1
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 1
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 1
ACM2_MOUSE Q9ERZ4 CHEMBL3197 Muscarinic Acetylcholine Receptor M2, Mouse 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 1
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 1
ACM4_RAT P08485 CHEMBL317 Muscarinic Acetylcholine Receptor M4, Rat 1
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
Z50594 Z50594 CHEMBL375 Mus Musculus 1

Most Common Rings