ZINC 12

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Names
Compounds (43)
Reactome (3)
Related By:
Pathway (19)
Organism (2)
Gene (3)
Org. Clust. (6)
ChEMBL (51)
Rings (0)

Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human (43 Compounds)

Swissprot:: ACHB4_HUMAN
Stitch:: ACHB4_HUMAN
UniProt:: P30926
ChEMBL:: CHEMBL3002
Reactome:: REACT_22352; REACT_22303; REACT_22223
PDB:: 2ASG (DOCK); CHRNB4

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	43	8	6	5
Binding ≤ 1μM	26	6	4	3
Functional ≤ 10μM	40	2	2	2

Reactome ID	Description	Species
REACT_22352	Highly calcium permeable nicotinic acetylcholine receptors	Homo sapiens
REACT_22303	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Homo sapiens
REACT_22223	Highly sodium permeable acetylcholine nicotinic receptors	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
ACHA2_HUMAN	Q15822	CHEMBL1794	Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human	23
ACHA3_HUMAN	P32297	CHEMBL3068	Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human	79
ACHA4_HUMAN	P43681	CHEMBL1882	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human	36
ACHA5_HUMAN	P30532	CHEMBL2454	Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human	4
ACHA6_HUMAN	Q15825	CHEMBL2356	Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human	4
ACHA_HUMAN	P02708	CHEMBL4808	Acetylcholine Receptor Protein Alpha Chain, Human	4
ACHB2_HUMAN	P17787	CHEMBL1883	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human	80
ACHB3_HUMAN	Q05901	CHEMBL2586	Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human	51

Highly calcium permeable postsynaptic nicotinic acetylcholine receptors

Uniprot	Swissprot	Chembl	Description	Number Shared
ACHA2_HUMAN	Q15822	CHEMBL1794	Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human	23
ACHA3_HUMAN	P32297	CHEMBL3068	Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human	79
ACHA4_HUMAN	P43681	CHEMBL1882	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human	36
ACHA5_HUMAN	P30532	CHEMBL2454	Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human	4
ACHA6_HUMAN	Q15825	CHEMBL2356	Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human	4
ACHA7_HUMAN	P36544	CHEMBL2492	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human	27
ACHA_HUMAN	P02708	CHEMBL4808	Acetylcholine Receptor Protein Alpha Chain, Human	4
ACHB2_HUMAN	P17787	CHEMBL1883	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human	80
ACHB3_HUMAN	Q05901	CHEMBL2586	Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human	51

Highly sodium permeable acetylcholine nicotinic receptors

Uniprot	Swissprot	Chembl	Description	Number Shared
ACHA3_HUMAN	P32297	CHEMBL3068	Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human	79
ACHA4_HUMAN	P43681	CHEMBL1882	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human	36
ACHB2_HUMAN	P17787	CHEMBL1883	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human	80
ACHD_HUMAN	Q07001	CHEMBL3011	Acetylcholine Receptor Protein Delta Chain, Human	6
ACHE_HUMAN	Q04844	CHEMBL2484	Acetylcholine Receptor Protein Epsilon Chain, Human	4
ACHG_HUMAN	P07510	CHEMBL2613	Acetylcholine Receptor Protein Gamma Chain, Human	4

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ACHB4_MOUSE	Q8R493	CHEMBL1255157	Neuronal Acetylcholine Receptor Subunit Beta-4, Mouse	12	3	1	0
ACHB4_RAT	P12392	CHEMBL2658	Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat	370	59	16	5

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ACHB2_HUMAN	P17787	CHEMBL1883	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human	64	13	8	7
ACHB3_HUMAN	Q05901	CHEMBL2586	Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human	24	5	3	2
ACHB_HUMAN	P11230	CHEMBL3355	Acetylcholine Receptor Protein Beta Chain, Human	4	2	1	0

Clustered By Gene (0)

Clustered By Organism (6)

Code	Description	Substances	Purchasable	Natural	In Man
ACHB4-1-E	Neuronal Acetylcholine Receptor Subunit Beta-4 (cluster #1 Of 7), Eukaryotic	98	14	1	0
ACHB4-2-E	Neuronal Acetylcholine Receptor Subunit Beta-4 (cluster #2 Of 7), Eukaryotic	51	7	8	2
ACHB4-3-E	Neuronal Acetylcholine Receptor Subunit Beta-4 (cluster #3 Of 7), Eukaryotic	84	6	0	1
ACHB4-4-E	Neuronal Acetylcholine Receptor Subunit Beta-4 (cluster #4 Of 7), Eukaryotic	2	2	2	2
ACHB4-5-E	Neuronal Acetylcholine Receptor Subunit Beta-4 (cluster #5 Of 7), Eukaryotic	153	30	6	3
ACHB4-6-E	Neuronal Acetylcholine Receptor Subunit Beta-4 (cluster #6 Of 7), Eukaryotic	21	8	3	0
ACHB4-7-E	Neuronal Acetylcholine Receptor Subunit Beta-4 (cluster #7 Of 7), Eukaryotic	1	1	1	0

Uniprot	Swissprot	Chembl	Description	Number Shared
ACHB2_HUMAN	P17787	CHEMBL1883	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human	80
ACHA3_HUMAN	P32297	CHEMBL3068	Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human	79
ACHB3_HUMAN	Q05901	CHEMBL2586	Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human	51
ACHA4_HUMAN	P43681	CHEMBL1882	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human	36
ACHB_HUMAN	P11230	CHEMBL3355	Acetylcholine Receptor Protein Beta Chain, Human	31
Z104283	Z104283	CHEMBL1907589	Neuronal Acetylcholine Receptor; Alpha4/beta2	31
ACHA7_HUMAN	P36544	CHEMBL2492	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human	26
ACHA2_HUMAN	Q15822	CHEMBL1794	Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human	23
ACHB4_RAT	P12392	CHEMBL2658	Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat	18
Z104290	Z104290	CHEMBL1907596	Neuronal Acetylcholine Receptor; Alpha4/beta2	18
ACHB2_RAT	P12390	CHEMBL3001	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Rat	17
ITA5_HUMAN	P08648	CHEMBL3955	Fibronectin Receptor Alpha, Human	13
ACHD_TORCA	P02718	CHEMBL3916	Acetylcholine Receptor Protein Delta Chain, Torca	12
Z104285	Z104285	CHEMBL1907591	Neuronal Acetylcholine Receptor; Alpha4/beta4	12
Z104288	Z104288	CHEMBL1907594	Neuronal Acetylcholine Receptor; Alpha3/beta4	12
ACHA7_RAT	Q05941	CHEMBL4980	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat	9
Z104282	Z104282	CHEMBL1907588	Acetylcholine Receptor; Alpha1/beta1/delta/gamma	9
Z104287	Z104287	CHEMBL1907593	Neuronal Acetylcholine Receptor; Alpha3/beta4	9
ACHA4_RAT	P09483	CHEMBL307	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Rat	6
ACHD_HUMAN	Q07001	CHEMBL3011	Acetylcholine Receptor Protein Delta Chain, Human	6
ACHA9_RAT	P43144	CHEMBL2585	Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Rat	5
ACHA_TORCA	P02710	CHEMBL3097	Acetylcholine Receptor Protein Alpha Chain, Torca	5
ACHB_TORCA	P02712	CHEMBL3803	Acetylcholine Receptor Protein Beta Chain, Torca	5
ACHG_TORCA	P02714	CHEMBL4019	Acetylcholine Receptor Protein Gamma Chain, Torca	5
ACH10_HUMAN	Q9GZZ6	CHEMBL2551	Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Human	4
ACHA2_RAT	P12389	CHEMBL2584	Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat	4
ACHA3_RAT	P04757	CHEMBL3818	Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Rat	4
ACHA5_HUMAN	P30532	CHEMBL2454	Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human	4
ACHA6_HUMAN	Q15825	CHEMBL2356	Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human	4
ACHA_HUMAN	P02708	CHEMBL4808	Acetylcholine Receptor Protein Alpha Chain, Human	4
ACHE_HUMAN	Q04844	CHEMBL2484	Acetylcholine Receptor Protein Epsilon Chain, Human	4
ACHG_HUMAN	P07510	CHEMBL2613	Acetylcholine Receptor Protein Gamma Chain, Human	4
Z104281	Z104281	CHEMBL1907587	Neuronal Acetylcholine Receptor; Alpha3/beta2	4
Z104284	Z104284	CHEMBL1907590	Neuronal Acetylcholine Receptor; Alpha2/beta4	4
Z104286	Z104286	CHEMBL1907592	Neuronal Acetylcholine Receptor; Alpha2/beta2	4
Z104289	Z104289	CHEMBL1907595	Neuronal Acetylcholine Receptor; Alpha4/beta4	4
ACH10_RAT	Q9JLB5	CHEMBL3461	Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Rat	3
ACHA4_MOUSE	O70174	CHEMBL4457	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Mouse	3
ACHA5_RAT	P20420	CHEMBL4960	Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Rat	3
ACHA6_RAT	P43143	CHEMBL4747	Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Rat	3
ACHA_RAT	P25108	CHEMBL3599	Acetylcholine Receptor Protein Alpha Chain, Rat	3
ACHB3_RAT	P12391	CHEMBL4568	Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat	3
ACHB_RAT	P25109	CHEMBL2666	Acetylcholine Receptor Protein Beta Chain, Rat	3
Q8BGP7_MOUSE	Q8BGP7	CHEMBL2235	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Mouse	3
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	2
ACHA4_CHICK	P09482	CHEMBL5569	Neuronal Acetylcholine Receptor Subunit Alpha-4, Chick	1
ACHA7_MOUSE	P49582	CHEMBL3365	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Mouse	1
ACHP_LYMST	P58154	CHEMBL6084	Acetylcholine-binding Protein, Lymst	1
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	1
Z104303	Z104303	CHEMBL1907609	Muscarinic Acetylcholine Receptor	1
Z50594	Z50594	CHEMBL375	Mus Musculus	1

Synonyms
Compounds (43)
Related By:
Pathway (19)
Organism (2)
Gene (3)
ChEMBL (51)
Org. Clust. (6)
Rings (0)

ZINC 12

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Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human (43 Compounds)

Compound Summary

Reactome Network (3)

Related Targets

Highly calcium permeable nicotinic acetylcholine receptors

Highly calcium permeable postsynaptic nicotinic acetylcholine receptors

Highly sodium permeable acetylcholine nicotinic receptors

By Organism (2)

By Gene (3)

Clustered By Gene (0)

Clustered By Organism (6)

By Shared ChEMBL Annotated Substances