ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (330)
Reactome (0)
Related By:
Pathway (0)
Organism (1)
Gene (0)
Org. Clust. (2)
ChEMBL (144)
Rings (36)

Alpha-1d Adrenergic Receptor, Rat (330 Compounds)

Swissprot:: ADA1D_RAT
Stitch:: ADA1D_RAT
UniProt:: P23944
ChEMBL:: CHEMBL326
PDB:: Adra1d

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	330	48	32	29
Binding ≤ 1μM	303	31	22	25
Functional ≤ 10μM	46	11	3	0

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	1,085	77	49	46

Clustered By Gene (0)

Clustered By Organism (2)

Code	Description	Substances	Purchasable	Natural	In Man
ADA1D-1-E	Alpha-1d Adrenergic Receptor (cluster #1 Of 3), Eukaryotic	1,330	97	62	55
ADA1D-2-E	Alpha-1d Adrenergic Receptor (cluster #2 Of 3), Eukaryotic	83	8	7	6
ADA1D-3-E	Alpha-1d Adrenergic Receptor (cluster #3 Of 3), Eukaryotic	15	1	0	0

Uniprot	Swissprot	Chembl	Description	Number Shared
ADA1A_RAT	P43140	CHEMBL319	Alpha-1a Adrenergic Receptor, Rat	228
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b Adrenergic Receptor, Human	201
ADA1A_BOVIN	P18130	CHEMBL4892	Alpha-1a Adrenergic Receptor, Bovin	106
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	85
ADA1B_MESAU	P18841	CHEMBL3122	Alpha-1b Adrenergic Receptor, Mesau	70
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	69
ADA1B_RAT	P15823	CHEMBL315	Alpha-1b Adrenergic Receptor, Rat	64
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	61
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	57
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	55
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	55
ADA1A_HUMAN	P35348	CHEMBL229	Alpha-1a Adrenergic Receptor, Human	53
Z104304	Z104304	CHEMBL1907610	Adrenergic Receptor Alpha-1	40
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	39
5HT2A_RAT	P14842	CHEMBL322	Serotonin 2a (5-HT2a) Receptor, Rat	35
DRD1_RAT	P18901	CHEMBL265	Dopamine D1 Receptor, Rat	29
5HT1A_RAT	P19327	CHEMBL273	Serotonin 1a (5-HT1a) Receptor, Rat	27
DRD3_RAT	P19020	CHEMBL3138	Dopamine D3 Receptor, Rat	27
5HT2C_RAT	P08909	CHEMBL324	Serotonin 2c (5-HT2c) Receptor, Rat	25
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	21
ADA2C_HUMAN	P18825	CHEMBL1916	Alpha-2c Adrenergic Receptor, Human	21
5HT2B_RAT	P30994	CHEMBL323	Serotonin 2b (5-HT2b) Receptor, Rat	20
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	19
5HT1B_HUMAN	P28222	CHEMBL1898	Serotonin 1b (5-HT1b) Receptor, Human	18
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	18
ADRB1_RAT	P18090	CHEMBL3252	Beta-1 Adrenergic Receptor, Rat	18
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	18
ADRB3_RAT	P26255	CHEMBL4031	Beta-3 Adrenergic Receptor, Rat	17
DRD4_RAT	P30729	CHEMBL3361	Dopamine D4 Receptor, Rat	17
DRD5_RAT	P25115	CHEMBL2281	Dopamine D5 Receptor, Rat	17
ADA2B_HUMAN	P18089	CHEMBL1942	Alpha-2b Adrenergic Receptor, Human	16
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	16
Z100766	Z100766	CHEMBL613712	Radical Scavenging Activity	14
5HT1F_RAT	P30940	CHEMBL4646	Serotonin 1f (5-HT1f) Receptor, Rat	13
ADRB2_CANFA	P54833	CHEMBL2289	Beta-2 Adrenergic Receptor, Canine	13
5HT1B_RAT	P28564	CHEMBL3459	Serotonin 1b (5-HT1b) Receptor, Rat	12
5HT1D_RAT	P28565	CHEMBL5450	Serotonin 1d (5-HT1d) Receptor, Rat	12
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	12
5HT7R_RAT	P32305	CHEMBL3223	Serotonin 7 (5-HT7) Receptor, Rat	10
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	9
ADA2A_BOVIN	Q28838	CHEMBL4744	Alpha-2a Adrenergic Receptor, Bovin	9
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	8
HRH1_RAT	P31390	CHEMBL4701	Histamine H1 Receptor, Rat	8
SCN1A_HUMAN	P35498	CHEMBL1845	Sodium Channel Protein Type I Alpha Subunit, Human	8
SCN2A_HUMAN	Q99250	CHEMBL4187	Sodium Channel Protein Type II Alpha Subunit, Human	8
SCN3A_HUMAN	Q9NY46	CHEMBL5163	Sodium Channel Protein Type III Alpha Subunit, Human	8
SCN8A_HUMAN	Q9UQD0	CHEMBL5202	Sodium Channel Protein Type VIII Alpha Subunit, Human	8
ADRB2_RAT	P10608	CHEMBL3754	Beta-2 Adrenergic Receptor, Rat	7
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	7
ADCY1_HUMAN	Q08828	CHEMBL2899	Brain Adenylate Cyclase 1, Human	6
ADCY2_HUMAN	Q08462	CHEMBL3760	Adenylate Cyclase Type II, Human	6
ADCY8_HUMAN	P40145	CHEMBL2960	Adenylate Cyclase Type VIII, Human	6
5HT2A_BOVIN	Q75Z89	CHEMBL3446	Serotonin 2a (5-HT2a) Receptor, Bovin	5
5HT4R_RAT	Q62758	CHEMBL4317	Serotonin 4 (5-HT4) Receptor, Rat	5
5HT5A_RAT	P35364	CHEMBL4655	Serotonin 5a (5-HT5a) Receptor, Rat	5
5HT5B_RAT	P35365	CHEMBL2619	Serotonin 5b (5-HT5b) Receptor, Rat	5
5HT6R_HUMAN	P50406	CHEMBL3371	Serotonin 6 (5-HT6) Receptor, Human	5
5HT6R_RAT	P31388	CHEMBL3372	Serotonin 6 (5-HT6) Receptor, Rat	5
5HT7R_HUMAN	P34969	CHEMBL3155	Serotonin 7 (5-HT7) Receptor, Human	5
ADRB2_HUMAN	P07550	CHEMBL210	Beta-2 Adrenergic Receptor, Human	5
Q9WTR4_RAT	Q9WTR4	CHEMBL304	Norepinephrine Transporter, Rat	5
5HT1D_HUMAN	P28221	CHEMBL1983	Serotonin 1d (5-HT1d) Receptor, Human	4
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	4
5HT2C_MOUSE	P34968	CHEMBL3006	Serotonin 2c (5-HT2c) Receptor, Mouse	4
5HT3A_RAT	P35563	CHEMBL2411	Serotonin 3a (5-HT3a) Receptor, Rat	4
5HT3B_RAT	Q9JJ16	CHEMBL3458	Serotonin 3b (5-HT3b) Receptor, Rat	4
ADRB1_HUMAN	P08588	CHEMBL213	Beta-1 Adrenergic Receptor, Human	4
CAC1C_RAT	P22002	CHEMBL3762	Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat	4
DRD1_HUMAN	P21728	CHEMBL2056	Dopamine D1 Receptor, Human	4
DRD2_BOVIN	P20288	CHEMBL3998	Dopamine D2 Receptor, Bovin	4
SC6A4_HUMAN	P31645	CHEMBL228	Serotonin Transporter, Human	4
SC6A4_RAT	P31652	CHEMBL313	Serotonin Transporter, Rat	4
Z104303	Z104303	CHEMBL1907609	Muscarinic Acetylcholine Receptor	4
5HT5A_HUMAN	P47898	CHEMBL3426	Serotonin 5a (5-HT5a) Receptor, Human	3
ACM1_RAT	P08482	CHEMBL276	Muscarinic Acetylcholine Receptor M1, Rat	3
ACM2_RAT	P10980	CHEMBL309	Muscarinic Acetylcholine Receptor M2, Rat	3
ACM5_RAT	P08911	CHEMBL277	Muscarinic Acetylcholine Receptor M5, Rat	3
ADA2A_MOUSE	Q01338	CHEMBL4075	Alpha-2a Adrenergic Receptor, Mouse	3
ADA2B_BOVIN	O77700	CHEMBL3523	Alpha-2b Adrenergic Receptor, Bovin	3
ADA2B_MOUSE	P30545	CHEMBL2405	Alpha-2b Adrenergic Receptor, Mouse	3
ADA2C_MOUSE	Q01337	CHEMBL4826	Alpha-2c Adrenergic Receptor, Mouse	3
DRD5_HUMAN	P21918	CHEMBL1850	Dopamine D5 Receptor, Human	3
HRH2_RAT	P25102	CHEMBL4654	Histamine H2 Receptor, Rat	3
HRH3_RAT	Q9QYN8	CHEMBL4124	Histamine H3 Receptor, Rat	3
HRH4_RAT	Q91ZY1	CHEMBL4468	Histamine H4 Receptor, Rat	3
OPRM_RAT	P33535	CHEMBL270	Mu Opioid Receptor, Rat	3
Q63380_RAT	Q63380	CHEMBL6184	Transporter, Rat	3
SC6A2_HUMAN	P23975	CHEMBL222	Norepinephrine Transporter, Human	3
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma Opioid Receptor, Rat	3
5HT1A_MOUSE	Q64264	CHEMBL3737	Serotonin 1a (5-HT1a) Receptor, Mouse	2
5HT1E_HUMAN	P28566	CHEMBL2182	Serotonin 1e (5-HT1e) Receptor, Human	2
5HT2A_MOUSE	P35363	CHEMBL5377	Serotonin 2a (5-HT2a) Receptor, Mouse	2
5HT2B_MOUSE	Q02152	CHEMBL2583	Serotonin 2b (5-HT2b) Receptor, Mouse	2
5HT3A_MOUSE	P23979	CHEMBL4972	Serotonin 3a (5-HT3a) Receptor, Mouse	2
ACM1_HUMAN	P11229	CHEMBL216	Muscarinic Acetylcholine Receptor M1, Human	2
ACM2_HUMAN	P08172	CHEMBL211	Muscarinic Acetylcholine Receptor M2, Human	2
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic Acetylcholine Receptor M3, Human	2
ACM3_RAT	P08483	CHEMBL320	Muscarinic Acetylcholine Receptor M3, Rat	2
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic Acetylcholine Receptor M4, Human	2
ACM5_HUMAN	P08912	CHEMBL2035	Muscarinic Acetylcholine Receptor M5, Human	2
ADA2A_PIG	P18871	CHEMBL2350	Alpha-2a Adrenergic Receptor, Pig	2
ADRB3_HUMAN	P13945	CHEMBL246	Beta-3 Adrenergic Receptor, Human	2
CAC1D_RAT	P27732	CHEMBL4132	Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat	2
CAC1S_RAT	Q02485	CHEMBL4108	Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Rat	2
DRD1_BOVIN	Q95136	CHEMBL2967	Dopamine D1 Receptor, Bovin	2
DRD1_PIG	P50130	CHEMBL5067	Dopamine D1 Receptor, Pig	2
DRD2_CHLAE	P52702	CHEMBL5456	Dopamine D2 Receptor, Chlae	2
DRD2_MOUSE	P61168	CHEMBL3427	Dopamine D2 Receptor, Mouse	2
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	2
Z102306	Z102306	CHEMBL613606	Aorta	2
5HT1F_HUMAN	P30939	CHEMBL1805	Serotonin 1f (5-HT1f) Receptor, Human	1
5HT2A_PIG	P50129	CHEMBL2490	Serotonin 2a (5-HT2a) Receptor, Pig	1
5HT3B_MOUSE	Q9JHJ5	CHEMBL3781	Serotonin 3b (5-HT3b) Receptor, Mouse	1
AA1R_RAT	P25099	CHEMBL318	Adenosine A1 Receptor, Rat	1
AA2AR_RAT	P30543	CHEMBL302	Adenosine A2a Receptor, Rat	1
ACM4_RAT	P08485	CHEMBL317	Muscarinic Acetylcholine Receptor M4, Rat	1
ADRB2_BOVIN	Q28044	CHEMBL3373	Beta-2 Adrenergic Receptor, Bovin	1
ADRB2_CAVPO	Q8K4Z4	CHEMBL5414	Beta-2 Adrenergic Receptor, Guinea Pig	1
AP2S1_RAT	P62744	CHEMBL1697667	AP-2 Complex Subunit Sigma, Rat	1
DRD1_MOUSE	Q61616	CHEMBL3071	Dopamine D1 Receptor, Mouse	1
EBP_HUMAN	Q15125	CHEMBL4931	3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human	1
ERG2_YEAST	P32352	CHEMBL3224	C-8 Sterol Isomerase, Yeast	1
HRH1_CAVPO	P31389	CHEMBL3943	Histamine H1 Receptor, Guinea Pig	1
HRH2_CAVPO	P47747	CHEMBL2882	Histamine H2 Receptor, Guinea Pig	1
HRH4_HUMAN	Q9H3N8	CHEMBL3759	Histamine H4 Receptor, Human	1
MDR1_HUMAN	P08183	CHEMBL4302	P-glycoprotein 1, Human	1
MT3_HUMAN	P25713	CHEMBL1250357	Metallothionein-3, Human	1
NISCH_HUMAN	Q9Y2I1	CHEMBL3923	Nischarin, Human	1
NPY1R_HUMAN	P25929	CHEMBL4777	Neuropeptide Y Receptor Type 1, Human	1
NPY5R_HUMAN	Q15761	CHEMBL4561	Neuropeptide Y Receptor Type 5, Human	1
OPRD_RAT	P33533	CHEMBL269	Delta Opioid Receptor, Rat	1
OPRK_RAT	P34975	CHEMBL3614	Kappa Opioid Receptor, Rat	1
PRIO_HUMAN	P04156	CHEMBL4869	Prion Protein, Human	1
Q4U254_9ENTO	Q4U254	CHEMBL2857	Human Rhinovirus A Protease, 9ento	1
Q72874_9HIV1	Q72874	CHEMBL243	Human Immunodeficiency Virus Type 1 Protease, 9hiv1	1
S22A1_HUMAN	O15245	CHEMBL5685	Solute Carrier Family 22 Member 1, Human	1
SC6A2_MOUSE	O55192	CHEMBL2370	Norepinephrine Transporter, Mouse	1
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	1
SC6A3_MOUSE	Q61327	CHEMBL2799	Dopamine Transporter, Mouse	1
SC6A3_RAT	P23977	CHEMBL338	Dopamine Transporter, Rat	1
SC6A4_MOUSE	Q60857	CHEMBL4642	Serotonin Transporter, Mouse	1
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	1
TYTR_TRYCR	P28593	CHEMBL5131	Trypanothione Reductase, Trycr	1
Z100491	Z100491	CHEMBL613288	Sigma 2 Receptor	1