| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 37 | 13 | 4 | 4 |
| Binding ≤ 1μM | 32 | 9 | 2 | 3 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_24968 | Retinoid metabolism and transport | Homo sapiens |
| REACT_11053 | Synthesis of bile acids and bile salts via 24-hydroxycholesterol | Homo sapiens |
| REACT_11048 | Synthesis of bile acids and bile salts via 27-hydroxycholesterol | Homo sapiens |
| REACT_11041 | Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | Homo sapiens |
| REACT_150149 | Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| AK1C1_HUMAN | Q04828 | CHEMBL5905 | Aldo-keto Reductase Family 1 Member C1, Human | 1 |
| TTHY_HUMAN | P02766 | CHEMBL3194 | Transthyretin, Human | 1 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| AK1C1_HUMAN | Q04828 | CHEMBL5905 | Aldo-keto Reductase Family 1 Member C1, Human | 1 |
| AK1C2_HUMAN | P52895 | CHEMBL5847 | Aldo-keto Reductase Family 1 Member C2, Human | 5 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| AK1C1_HUMAN | Q04828 | CHEMBL5905 | Aldo-keto Reductase Family 1 Member C1, Human | 1 |
| AK1C2_HUMAN | P52895 | CHEMBL5847 | Aldo-keto Reductase Family 1 Member C2, Human | 5 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| AK1C1_HUMAN | Q04828 | CHEMBL5905 | Aldo-keto Reductase Family 1 Member C1, Human | 1 |
| AK1C2_HUMAN | P52895 | CHEMBL5847 | Aldo-keto Reductase Family 1 Member C2, Human | 5 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| PGH1_HUMAN | P23219 | CHEMBL221 | Cyclooxygenase-1, Human | 2 |
| PGH2_HUMAN | P35354 | CHEMBL230 | Cyclooxygenase-2, Human | 2 |
| PTGES_HUMAN | O14684 | CHEMBL5658 | Prostaglandin E Synthase, Human | 1 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| AK1C1_HUMAN | Q04828 | CHEMBL5905 | Aldo-keto Reductase Family 1 Member C1, Human | 17 | 6 | 2 | 1 |
| AK1C2_HUMAN | P52895 | CHEMBL5847 | Aldo-keto Reductase Family 1 Member C2, Human | 19 | 9 | 3 | 1 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| AK1C2_HUMAN | P52895 | CHEMBL5847 | Aldo-keto Reductase Family 1 Member C2, Human | 5 |
| PGH1_HUMAN | P23219 | CHEMBL221 | Cyclooxygenase-1, Human | 2 |
| PGH1_SHEEP | P05979 | CHEMBL2949 | Cyclooxygenase-1, Sheep | 2 |
| PGH2_HUMAN | P35354 | CHEMBL230 | Cyclooxygenase-2, Human | 2 |
| AK1C1_HUMAN | Q04828 | CHEMBL5905 | Aldo-keto Reductase Family 1 Member C1, Human | 1 |
| CXCR1_HUMAN | P25024 | CHEMBL4029 | Interleukin-8 Receptor A, Human | 1 |
| FABPL_RAT | P02692 | CHEMBL5738 | Fatty Acid-binding Protein, Liver, Rat | 1 |
| IL8_HUMAN | P10145 | CHEMBL2157 | Interleukin-8, Human | 1 |
| LIPS_RAT | P15304 | CHEMBL5582 | Hormone-sensitive Lipase, Rat | 1 |
| PERM_HUMAN | P05164 | CHEMBL2439 | Myeloperoxidase, Human | 1 |
| PGH1_BOVIN | O62664 | CHEMBL2860 | Cyclooxygenase-1, Bovin | 1 |
| PGH1_RAT | Q63921 | CHEMBL4042 | Cyclooxygenase-1, Rat | 1 |
| PGH2_MOUSE | Q05769 | CHEMBL4321 | Cyclooxygenase-2, Mouse | 1 |
| PGH2_RAT | P35355 | CHEMBL2977 | Cyclooxygenase-2, Rat | 1 |
| PGH2_SHEEP | P79208 | CHEMBL4102 | Cyclooxygenase-2, Sheep | 1 |
| PTGES_HUMAN | O14684 | CHEMBL5658 | Prostaglandin E Synthase, Human | 1 |
| TTHY_HUMAN | P02766 | CHEMBL3194 | Transthyretin, Human | 1 |