UCSF

Aldehyde Dehydrogenase, Human (54 Compounds)

Swissprot:
ALDH2_HUMAN
Stitch:
ALDH2_HUMAN
UniProt:
P05091
ChEMBL:
CHEMBL1935
Reactome:
REACT_34
REACT_15532
PDB:
1CW3 (DOCK)
1NZW (DOCK)
1NZX (DOCK)
1NZZ (DOCK)
1O00 (DOCK)
1O01 (DOCK)
1O02 (DOCK)
1O04 (DOCK)
1O05 (DOCK)
1ZUM (DOCK)
2ONM (DOCK)
2ONN (DOCK)
2ONO (DOCK)
2ONP (DOCK)
2VLE (DOCK)
3INJ (DOCK)
3INL (DOCK)
3N80 (DOCK)
3N81 (DOCK)
3N82 (DOCK)
3N83 (DOCK)
3SZ9 (DOCK)
ALDH2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 54 17 8 4
Binding ≤ 1μM 37 12 5 4
Functional ≤ 10μM 2 0 0 0

Reactome Network (2)

Reactome ID Description Species
REACT_34 Ethanol oxidation Homo sapiens
REACT_15532 Metabolism of serotonin Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 21
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ALDH2_RAT P11884 CHEMBL2812 Aldehyde Dehydrogenase, Rat 5 1 1 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
ALDH2-1-E Aldehyde Dehydrogenase (cluster #1 Of 2), Eukaryotic 58 17 8 4
ALDH2-2-E Aldehyde Dehydrogenase (cluster #2 Of 2), Eukaryotic 1 1 1 1
Uniprot Swissprot Chembl Description Number Shared
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 19
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 19
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 1
DHB3_HUMAN P37058 CHEMBL4234 Estradiol 17-beta-dehydrogenase 3, Human 1
ESR1_HUMAN P03372 CHEMBL206 Estrogen Receptor Alpha, Human 1
ESR2_HUMAN Q92731 CHEMBL242 Estrogen Receptor Beta, Human 1