ANDR_HUMAN - Androgen Receptor, Human | ZINC Is Not Commercial - A database of commercially-available compounds

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	1,635	98	33	25
Binding ≤ 1μM	1,334	89	32	24
Functional ≤ 10μM	1,125	70	24	23

Reactome ID	Description	Species
REACT_15525	Nuclear Receptor transcription pathway	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
ERR1_HUMAN	P11474	CHEMBL3429	Estrogen-related Receptor Alpha, Human	1
ERR2_HUMAN	O95718	CHEMBL3751	Estrogen-related Receptor Beta, Human	1
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	144
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	150
NR1H2_HUMAN	P55055	CHEMBL4093	LXR-beta, Human	1
PRGR_HUMAN	P06401	CHEMBL208	Progesterone Receptor, Human	525
THA_HUMAN	P10827	CHEMBL1860	Thyroid Hormone Receptor Alpha, Human	2
THB_HUMAN	P10828	CHEMBL1947	Thyroid Hormone Receptor Beta-1, Human	1
VDR_HUMAN	P11473	CHEMBL1977	Vitamin D Receptor, Human	6

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ANDR_MOUSE	P19091	CHEMBL3056	Androgen Receptor, Mouse	20	4	4	4
ANDR_RAT	P15207	CHEMBL3072	Androgen Receptor, Rat	178	13	11	10

Clustered By Gene (0)

Clustered By Organism (3)

Code	Description	Substances	Purchasable	Natural	In Man
ANDR-1-E	Androgen Receptor (cluster #1 Of 4), Eukaryotic	1,182	18	8	11
ANDR-2-E	Androgen Receptor (cluster #2 Of 4), Eukaryotic	358	59	30	19
ANDR-3-E	Androgen Receptor (cluster #3 Of 4), Eukaryotic	115	3	0	1
ANDR-4-E	Androgen Receptor (cluster #4 Of 4), Eukaryotic	194	29	6	5

Uniprot	Swissprot	Chembl	Description	Number Shared
PRGR_HUMAN	P06401	CHEMBL208	Progesterone Receptor, Human	522
GCR_HUMAN	P04150	CHEMBL2034	Glucocorticoid Receptor, Human	404
MCR_HUMAN	P08235	CHEMBL1994	Mineralocorticoid Receptor, Human	209
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	148
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	134
Z80243	Z80243	CHEMBL614334	MDA-MB-453 (Breast Adenocarcinoma Cells)	33
MCR_RAT	P22199	CHEMBL3507	Mineralocorticoid Receptor, Rat	18
Q5EM59_BOVIN	Q5EM59	CHEMBL3953	Androgen Receptor, Bovin	18
ANDR_RAT	P15207	CHEMBL3072	Androgen Receptor, Rat	17
CP17A_HUMAN	P05093	CHEMBL3522	Cytochrome P450 17A1, Human	16
ANDR_MOUSE	P19091	CHEMBL3056	Androgen Receptor, Mouse	14
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	11
NR1I2_HUMAN	O75469	CHEMBL3401	Pregnane X Receptor, Human	6
VDR_HUMAN	P11473	CHEMBL1977	Vitamin D Receptor, Human	6
GCR_RAT	P06536	CHEMBL3368	Glucocorticoid Receptor, Rat	5
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	5
PRGR_RABIT	P06186	CHEMBL3456	Progesterone Receptor, Rabit	4
PRGR_RAT	Q63449	CHEMBL2596	Progesterone Receptor, Rat	4
Z80110	Z80110	CHEMBL613507	CV-1 (Kidney Cells)	4
GCR_MOUSE	P06537	CHEMBL3144	Glucocorticoid Receptor, Mouse	3
SHBG_HUMAN	P04278	CHEMBL3305	Testis-specific Androgen-binding Protein, Human	3
Z81170	Z81170	CHEMBL612518	LNCaP (Prostate Carcinoma)	3
CP19A_HUMAN	P11511	CHEMBL1978	Cytochrome P450 19A1, Human	2
ERG2_YEAST	P32352	CHEMBL3224	C-8 Sterol Isomerase, Yeast	2
ESR1_RAT	P06211	CHEMBL2724	Estrogen Receptor Alpha, Rat	2
ESR2_RAT	Q62986	CHEMBL3021	Estrogen Receptor Beta, Rat	2
FABPL_RAT	P02692	CHEMBL5738	Fatty Acid-binding Protein, Liver, Rat	2
GPBAR_HUMAN	Q8TDU6	CHEMBL5409	G-protein Coupled Bile Acid Receptor 1, Human	2
PRGR_CHICK	P07812	CHEMBL3304	Progesterone Receptor, Chick	2
S5A1_RAT	P24008	CHEMBL3422	Steroid 5-alpha-reductase 1, Rat	2
S5A2_RAT	P31214	CHEMBL5099	Steroid 5-alpha-reductase 2, Rat	2
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	2
SHBG_RAT	P08689	CHEMBL4932	Testis-specific Androgen-binding Protein, Rat	2
THA_HUMAN	P10827	CHEMBL1860	Thyroid Hormone Receptor Alpha, Human	2
Z80418	Z80418	CHEMBL612557	RAW264.7 (Monocytic-macrophage Leukemia Cells)	2
Z80491	Z80491	CHEMBL614163	SK-N-MC (Neuroepithelioma Cells)	2
Z80712	Z80712	CHEMBL614361	T47D (Breast Carcinoma Cells)	2
Z80951	Z80951	CHEMBL614822	NIH3T3 (Fibroblasts)	2
AA1R_RAT	P25099	CHEMBL318	Adenosine A1 Receptor, Rat	1
AA2AR_RAT	P30543	CHEMBL302	Adenosine A2a Receptor, Rat	1
AA2BR_RAT	P29276	CHEMBL2592	Adenosine A2b Receptor, Rat	1
ERR1_HUMAN	P11474	CHEMBL3429	Estrogen-related Receptor Alpha, Human	1
ERR2_HUMAN	O95718	CHEMBL3751	Estrogen-related Receptor Beta, Human	1
ESR1_BOVIN	P49884	CHEMBL2930	Estrogen Receptor Alpha, Bovin	1
ESR1_MOUSE	P19785	CHEMBL3065	Estrogen Receptor Alpha, Mouse	1
ESR2_MOUSE	O08537	CHEMBL2995	Estrogen Receptor Beta, Mouse	1
GLNA_HUMAN	P15104	CHEMBL4612	Glutamine Synthetase, Human	1
GPER_HUMAN	Q99527	CHEMBL5872	G-protein Coupled Estrogen Receptor 1, Human	1
NR1H2_HUMAN	P55055	CHEMBL4093	LXR-beta, Human	1
NR1H3_HUMAN	Q13133	CHEMBL2808	LXR-alpha, Human	1
NR1H4_HUMAN	Q96RI1	CHEMBL2047	Bile Acid Receptor FXR, Human	1
NR1H4_MOUSE	Q60641	CHEMBL5343	Bile Acid Receptor, Mouse	1
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	1
THB_HUMAN	P10828	CHEMBL1947	Thyroid Hormone Receptor Beta-1, Human	1
VP16_HHV11	P06492	CHEMBL4218	Alpha Trans-inducing Protein (VP16), Hhv11	1
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	1
Z50607	Z50607	CHEMBL378	Human Immunodeficiency Virus 1	1
Z50652	Z50652	CHEMBL613740	Influenza A Virus	1
Z80453	Z80453	CHEMBL614897	SC-3	1