UCSF

Monoamine Oxidase B, Rat (501 Compounds)

Swissprot:
AOFB_RAT
Stitch:
AOFB_RAT
UniProt:
P19643
ChEMBL:
CHEMBL2993
Reactome:
REACT_230115
PDB:
Maob

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 501 96 19 21
Binding ≤ 1μM 322 62 12 15

Reactome Network (1)

Reactome ID Description Species
REACT_230115 Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O2 Rattus norvegicus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
AOFB_BOVIN P56560 CHEMBL2756 Monoamine Oxidase B, Bovin 130 44 4 1
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 606 196 53 32
AOFB_MOUSE Q8BW75 CHEMBL3050 Monoamine Oxidase B, Mouse 3 2 2 1

Clustered By Gene (0)

Clustered By Organism (7)

Code Description Substances Purchasable Natural In Man
AOFB-1-E Monoamine Oxidase B (cluster #1 Of 8), Eukaryotic 224 70 18 20
AOFB-2-E Monoamine Oxidase B (cluster #2 Of 8), Eukaryotic 531 132 22 11
AOFB-3-E Monoamine Oxidase B (cluster #3 Of 8), Eukaryotic 40 15 2 3
AOFB-4-E Monoamine Oxidase B (cluster #4 Of 8), Eukaryotic 333 77 18 8
AOFB-5-E Monoamine Oxidase B (cluster #5 Of 8), Eukaryotic 16 7 0 0
AOFB-6-E Monoamine Oxidase B (cluster #6 Of 8), Eukaryotic 83 18 9 3
AOFB-7-E Monoamine Oxidase B (cluster #7 Of 8), Eukaryotic 1 1 1 0
AOFB-8-E Monoamine Oxidase B (cluster #8 Of 8), Eukaryotic 12 3 0 0
Uniprot Swissprot Chembl Description Number Shared
AOFA_RAT P21396 CHEMBL3358 Monoamine Oxidase A, Rat 302
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 54
NISCH_HUMAN Q9Y2I1 CHEMBL3923 Nischarin, Human 40
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 39
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 22
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 21
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 21
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 20
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 20
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 16
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 15
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 11
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 6
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 4
AOC3_HUMAN Q16853 CHEMBL3437 Amine Oxidase, Copper Containing, Human 3
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 2
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 2
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 2
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 2
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 2
AOFA_BOVIN P21398 CHEMBL3254 Monoamine Oxidase A, Bovin 2
SCN1A_RAT P04774 CHEMBL4906 Sodium Channel Protein Type I Alpha Subunit, Rat 2
SCN2A_RAT P04775 CHEMBL3399 Sodium Channel Protein Type II Alpha Subunit, Rat 2
SCN3A_RAT P08104 CHEMBL4966 Sodium Channel Protein Type III Alpha Subunit, Rat 2
SCN8A_RAT O88420 CHEMBL2752 Sodium Channel Protein Type VIII Alpha Subunit, Rat 2
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 2
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 1
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 1
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 1
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 1
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 1
5HT5A_MOUSE P30966 CHEMBL3597 Serotonin 5a (5-HT5a) Receptor, Mouse 1
ALDH2_RAT P11884 CHEMBL2812 Aldehyde Dehydrogenase, Rat 1
AOC3_RAT O08590 CHEMBL4592 Amine Oxidase, Copper Containing, Rat 1
AOFB_BOVIN P56560 CHEMBL2756 Monoamine Oxidase B, Bovin 1
B5SU02_9CNID B5SU02 CHEMBL1075028 Alpha Carbonic Anhydrase, 9cnid 1
C0IX24_9CNID C0IX24 CHEMBL1649055 Carbonic Anhydrase, 9cnid 1
CAH13_HUMAN Q8N1Q1 CHEMBL3912 Carbonic Anhydrase XIII, Human 1
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 1
CAH15_MOUSE Q99N23 CHEMBL5973 Carbonic Anhydrase 15, Mouse 1
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 1
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 1
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 1
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 1
CAH5B_HUMAN Q9Y2D0 CHEMBL3969 Carbonic Anhydrase VB, Human 1
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 1
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 1
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 1
CAN_YEAST P53615 CHEMBL5931 Carbonic Anhydrase, Yeast 1
CYNT_HELPY O24855 CHEMBL4211 Carbonic Anhydrase 1, Helpy 1
CYNT_MYCTU O53573 CHEMBL6068 Carbonic Anhydrase, Myctu 1
DYR1A_HUMAN Q13627 CHEMBL2292 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Human 1
DYRK2_HUMAN Q92630 CHEMBL4376 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 2, Human 1
DYRK3_HUMAN O43781 CHEMBL4575 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 3, Human 1
HPGDS_HUMAN O60760 CHEMBL5879 Hematopoietic Prostaglandin D Synthase, Human 1
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 1
NISCH_RAT Q4G017 CHEMBL5221 Nischarin, Rat 1
P96878_MYCTU P96878 CHEMBL5767 PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE), Myctu 1
PIM3_HUMAN Q86V86 CHEMBL5407 Serine/threonine-protein Kinase PIM3, Human 1
PNMT_BOVIN P10938 CHEMBL2331 Phenylethanolamine N-methyltransferase, Bovin 1
Q3I4V7_CRYNV Q3I4V7 CHEMBL1697676 Carbonic Anhydrase 2, Crynv 1
Q5AJ71_CANAL Q5AJ71 CHEMBL5337 Carbonic Anhydrase, Canal 1
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 1

Most Common Rings