| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 61 | 7 | 5 | 4 |
| Binding ≤ 1μM | 42 | 2 | 1 | 0 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_6769 | Activation of ATR in response to replication stress | Homo sapiens |
| REACT_897 | G2/M DNA damage checkpoint | Homo sapiens |
| REACT_75792 | Meiotic synapsis | Homo sapiens |
| REACT_200780 | Regulation of HSF1-mediated heat shock response | Homo sapiens |
| REACT_18265 | Regulation of the Fanconi anemia pathway | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| ATM_HUMAN | Q13315 | CHEMBL3797 | Serine-protein Kinase ATM, Human | 18 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| ATM_HUMAN | Q13315 | CHEMBL3797 | Serine-protein Kinase ATM, Human | 18 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| ATM_HUMAN | Q13315 | CHEMBL3797 | Serine-protein Kinase ATM, Human | 18 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| ATR-1-E | Serine-protein Kinase ATR (cluster #1 Of 2), Eukaryotic | 60 | 6 | 4 | 4 |
| ATR-2-E | Serine-protein Kinase ATR (cluster #2 Of 2), Eukaryotic | 1 | 1 | 1 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| PRKDC_HUMAN | P78527 | CHEMBL3142 | DNA-dependent Protein Kinase, Human | 27 |
| ATM_HUMAN | Q13315 | CHEMBL3797 | Serine-protein Kinase ATM, Human | 18 |
| MTOR_HUMAN | P42345 | CHEMBL2842 | FK506 Binding Protein 12, Human | 2 |
| PK3CA_HUMAN | P42336 | CHEMBL4005 | PI3-kinase P110-alpha Subunit, Human | 2 |
| PK3CG_HUMAN | P48736 | CHEMBL3267 | PI3-kinase P110-gamma Subunit, Human | 2 |