Caspase-1, Human (975 Compounds)

Swissprot:: CASP1_HUMAN
Stitch:: CASP1_HUMAN
UniProt:: P29466
ChEMBL:: CHEMBL4801
Reactome:: REACT_23950; REACT_75776; REACT_75777; REACT_75892; REACT_75808
PDB:: 1BMQ (DOCK); 1IBC (DOCK); 1ICE (DOCK); 1RWK (DOCK); 1RWM (DOCK); 1RWN (DOCK); 1RWO (DOCK); 1RWP (DOCK); 1RWV (DOCK); 1RWW (DOCK); 1RWX (DOCK); 1SC1 (DOCK); 1SC3 (DOCK); 1SC4 (DOCK); 2FQQ (DOCK); 2H48 (DOCK); 2H4W (DOCK); 2H4Y (DOCK); 2H51 (DOCK); 2H54 (DOCK); 2HBQ (DOCK); 2HBR (DOCK); 2HBY (DOCK); 2HBZ (DOCK); 3D6F (DOCK); 3D6H (DOCK); 3D6M (DOCK); 3E4C (DOCK); 3NS7 (DOCK); CASP1

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	975	16	2	1
Binding ≤ 1μM	737	8	1	1

Uniprot	Swissprot	Chembl	Description	Number Shared
CASP2_HUMAN	P42575	CHEMBL4884	Caspase-2, Human	2
CASP4_HUMAN	P49662	CHEMBL2226	Caspase-4, Human	4
CASP8_HUMAN	Q14790	CHEMBL3776	Caspase-8, Human	417
CASP9_HUMAN	P55211	CHEMBL2273	Caspase-9, Human	8

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
CASP1_MOUSE	P29452	CHEMBL4800	Caspase-1, Mouse	45	1	0	0

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
CASP2_HUMAN	P42575	CHEMBL4884	Caspase-2, Human	75	2	1	2
CASP3_HUMAN	P42574	CHEMBL2334	Caspase-3, Human	987	29	1	5
CASP4_HUMAN	P49662	CHEMBL2226	Caspase-4, Human	5	0	0	0
CASP5_HUMAN	P51878	CHEMBL3131	Caspase-5, Human	4	0	0	0
CASP6_HUMAN	P55212	CHEMBL3308	Caspase-6, Human	171	7	0	1
CASP7_HUMAN	P55210	CHEMBL3468	Caspase-7, Human	433	10	0	2
CASP8_HUMAN	Q14790	CHEMBL3776	Caspase-8, Human	444	4	1	2
CASP9_HUMAN	P55211	CHEMBL2273	Caspase-9, Human	11	2	0	0
CASPA_HUMAN	Q92851	CHEMBL5037	Caspase-10, Human	4	0	0	0
CASPE_HUMAN	P31944	CHEMBL5991	Caspase-14, Human	1	0	0	0

Code	Description	Substances	Purchasable	Natural	In Man
CASP1-1-E	Caspase-1 (cluster #1 Of 3), Eukaryotic	985	9	1	1
CASP1-2-E	Caspase-1 (cluster #2 Of 3), Eukaryotic	29	7	0	0
CASP1-3-E	Caspase-1 (cluster #3 Of 3), Eukaryotic	1	1	1	0

Uniprot	Swissprot	Chembl	Description	Number Shared
CASP8_HUMAN	Q14790	CHEMBL3776	Caspase-8, Human	417
CASP3_HUMAN	P42574	CHEMBL2334	Caspase-3, Human	369
CASP7_HUMAN	P55210	CHEMBL3468	Caspase-7, Human	279
CASP6_HUMAN	P55212	CHEMBL3308	Caspase-6, Human	131
CASP1_MOUSE	P29452	CHEMBL4800	Caspase-1, Mouse	11
CASP9_HUMAN	P55211	CHEMBL2273	Caspase-9, Human	8
MMP3_HUMAN	P08254	CHEMBL283	Matrix Metalloproteinase 3, Human	5
CAN1_HUMAN	P07384	CHEMBL3891	Calpain 1, Human	4
CASP4_HUMAN	P49662	CHEMBL2226	Caspase-4, Human	4
CASP5_HUMAN	P51878	CHEMBL3131	Caspase-5, Human	4
CASPA_HUMAN	Q92851	CHEMBL5037	Caspase-10, Human	4
CATB_HUMAN	P07858	CHEMBL4072	Cathepsin B, Human	4
CASP2_HUMAN	P42575	CHEMBL4884	Caspase-2, Human	2
CATB_RAT	P00787	CHEMBL2602	Cathepsin B, Rat	2
ACES_HUMAN	P22303	CHEMBL220	Acetylcholinesterase, Human	1
CHLE_HUMAN	P06276	CHEMBL1914	Butyrylcholinesterase, Human	1