UCSF

Caspase-1, Human (975 Compounds)

Swissprot:
CASP1_HUMAN
Stitch:
CASP1_HUMAN
UniProt:
P29466
ChEMBL:
CHEMBL4801
Reactome:
REACT_23950
REACT_75776
REACT_75777
REACT_75892
REACT_75808
PDB:
1BMQ (DOCK)
1IBC (DOCK)
1ICE (DOCK)
1RWK (DOCK)
1RWM (DOCK)
1RWN (DOCK)
1RWO (DOCK)
1RWP (DOCK)
1RWV (DOCK)
1RWW (DOCK)
1RWX (DOCK)
1SC1 (DOCK)
1SC3 (DOCK)
1SC4 (DOCK)
2FQQ (DOCK)
2H48 (DOCK)
2H4W (DOCK)
2H4Y (DOCK)
2H51 (DOCK)
2H54 (DOCK)
2HBQ (DOCK)
2HBR (DOCK)
2HBY (DOCK)
2HBZ (DOCK)
3D6F (DOCK)
3D6H (DOCK)
3D6M (DOCK)
3E4C (DOCK)
3NS7 (DOCK)
CASP1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 975 16 2 1
Binding ≤ 1μM 737 8 1 1
Uniprot Swissprot Chembl Description Number Shared
CASP2_HUMAN P42575 CHEMBL4884 Caspase-2, Human 2
CASP4_HUMAN P49662 CHEMBL2226 Caspase-4, Human 4
CASP8_HUMAN Q14790 CHEMBL3776 Caspase-8, Human 417
CASP9_HUMAN P55211 CHEMBL2273 Caspase-9, Human 8
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CASP1_MOUSE P29452 CHEMBL4800 Caspase-1, Mouse 45 1 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CASP2_HUMAN P42575 CHEMBL4884 Caspase-2, Human 75 2 1 2
CASP3_HUMAN P42574 CHEMBL2334 Caspase-3, Human 987 29 1 5
CASP4_HUMAN P49662 CHEMBL2226 Caspase-4, Human 5 0 0 0
CASP5_HUMAN P51878 CHEMBL3131 Caspase-5, Human 4 0 0 0
CASP6_HUMAN P55212 CHEMBL3308 Caspase-6, Human 171 7 0 1
CASP7_HUMAN P55210 CHEMBL3468 Caspase-7, Human 433 10 0 2
CASP8_HUMAN Q14790 CHEMBL3776 Caspase-8, Human 444 4 1 2
CASP9_HUMAN P55211 CHEMBL2273 Caspase-9, Human 11 2 0 0
CASPA_HUMAN Q92851 CHEMBL5037 Caspase-10, Human 4 0 0 0
CASPE_HUMAN P31944 CHEMBL5991 Caspase-14, Human 1 0 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
CASP1-1-E Caspase-1 (cluster #1 Of 3), Eukaryotic 985 9 1 1
CASP1-2-E Caspase-1 (cluster #2 Of 3), Eukaryotic 29 7 0 0
CASP1-3-E Caspase-1 (cluster #3 Of 3), Eukaryotic 1 1 1 0
Uniprot Swissprot Chembl Description Number Shared
CASP8_HUMAN Q14790 CHEMBL3776 Caspase-8, Human 417
CASP3_HUMAN P42574 CHEMBL2334 Caspase-3, Human 369
CASP7_HUMAN P55210 CHEMBL3468 Caspase-7, Human 279
CASP6_HUMAN P55212 CHEMBL3308 Caspase-6, Human 131
CASP1_MOUSE P29452 CHEMBL4800 Caspase-1, Mouse 11
CASP9_HUMAN P55211 CHEMBL2273 Caspase-9, Human 8
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 5
CAN1_HUMAN P07384 CHEMBL3891 Calpain 1, Human 4
CASP4_HUMAN P49662 CHEMBL2226 Caspase-4, Human 4
CASP5_HUMAN P51878 CHEMBL3131 Caspase-5, Human 4
CASPA_HUMAN Q92851 CHEMBL5037 Caspase-10, Human 4
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 4
CASP2_HUMAN P42575 CHEMBL4884 Caspase-2, Human 2
CATB_RAT P00787 CHEMBL2602 Cathepsin B, Rat 2
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 1
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 1