| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 45 | 1 | 0 | 0 |
| Binding ≤ 1μM | 37 | 1 | 0 | 0 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_198700 | Interleukin-1 processing | Mus musculus |
| REACT_198662 | The AIM2 inflammasome | Mus musculus |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| CASP1_HUMAN | P29466 | CHEMBL4801 | Caspase-1, Human | 975 | 16 | 2 | 1 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| CASP4_MOUSE | P70343 | CHEMBL1075276 | Caspase-4, Mouse | 0 | 0 | 0 | 0 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| CASP1-1-E | Caspase-1 (cluster #1 Of 3), Eukaryotic | 985 | 9 | 1 | 1 |
| CASP1-2-E | Caspase-1 (cluster #2 Of 3), Eukaryotic | 29 | 7 | 0 | 0 |
| CASP1-3-E | Caspase-1 (cluster #3 Of 3), Eukaryotic | 1 | 1 | 1 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| CASP3_HUMAN | P42574 | CHEMBL2334 | Caspase-3, Human | 20 |
| CASP1_HUMAN | P29466 | CHEMBL4801 | Caspase-1, Human | 11 |
| CASP8_HUMAN | Q14790 | CHEMBL3776 | Caspase-8, Human | 7 |
| CASP9_HUMAN | P55211 | CHEMBL2273 | Caspase-9, Human | 7 |
| CASP6_HUMAN | P55212 | CHEMBL3308 | Caspase-6, Human | 5 |
| CASP7_HUMAN | P55210 | CHEMBL3468 | Caspase-7, Human | 4 |
| CAN1_HUMAN | P07384 | CHEMBL3891 | Calpain 1, Human | 2 |
| CATB_HUMAN | P07858 | CHEMBL4072 | Cathepsin B, Human | 2 |
| CATB_RAT | P00787 | CHEMBL2602 | Cathepsin B, Rat | 2 |