UCSF

Lanosterol 14-alpha Demethylase, Myctu (20 Compounds)

Swissprot:
CP51_MYCTU
Stitch:
CP51_MYCTU
UniProt:
P0A512
ChEMBL:
CHEMBL5090
PDB:
1E9X (DOCK)
1EA1 (DOCK)
1H5Z (DOCK)
1U13 (DOCK)
1X8V (DOCK)
2BZ9 (DOCK)
2CI0 (DOCK)
2CIB (DOCK)
2VKU (DOCK)
2W09 (DOCK)
2W0A (DOCK)
2W0B (DOCK)

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 20 20 10 9
Binding ≤ 1μM 6 6 6 6

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CP51_TRYCC Q7Z1V1 CHEMBL1075110 Sterol 14-alpha Demethylase, Trycc 2 2 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CP121_MYCTU P0A514 CHEMBL1681615 Cytochrome P450 121, Myctu 1 1 1 1

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
CP51-1-B Sterol 14-alpha Demethylase (cluster #1 Of 2), Bacterial 17 17 10 8
CP51-1-E Sterol 14-alpha Demethylase (cluster #1 Of 1), Eukaryotic 2 2 0 0
CP51-2-B Sterol 14-alpha Demethylase (cluster #2 Of 2), Bacterial 3 3 0 1
Uniprot Swissprot Chembl Description Number Shared
AMPC_ECOLI P00811 CHEMBL2026 Beta-lactamase, Ecoli 5
CP17A_HUMAN P05093 CHEMBL3522 Cytochrome P450 17A1, Human 5
CP51A_HUMAN Q16850 CHEMBL3849 Cytochrome P450 51, Human 5
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 3
CP19A_RAT P22443 CHEMBL3859 Cytochrome P450 19A1, Rat 2
Q96W81_ASPFM Q96W81 CHEMBL1681624 14-alpha Sterol Demethylase, Aspfm 2
CP121_MYCTU P0A514 CHEMBL1681615 Cytochrome P450 121, Myctu 1
I23O1_HUMAN P14902 CHEMBL4685 Indoleamine 2,3-dioxygenase, Human 1
KCNA3_HUMAN P22001 CHEMBL4633 Voltage-gated Potassium Channel Subunit Kv1.3, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
KCNN4_HUMAN O15554 CHEMBL4305 Intermediate Conductance Calcium-activated Potassium Channel Protein 4, Human 1
MDHM_PIG P00346 CHEMBL3444 Malate Dehydrogenase Mitochondrial, Pig 1
Q4WNT5_ASPFU Q4WNT5 CHEMBL1681623 14-alpha Sterol Demethylase Cyp51A, Aspfu 1
Z50442 Z50442 CHEMBL366 Candida Albicans 1

Most Common Rings