| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 6 | 0 | 0 | 0 |
| Binding ≤ 1μM | 3 | 0 | 0 | 0 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_228096 | misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling | Homo sapiens |
| REACT_200643 | negative regulation of TCF-dependent signaling by WNT ligand antagonists | Homo sapiens |
| REACT_200777 | TCF dependent signaling in response to WNT | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| GSK3B_HUMAN | P49841 | CHEMBL262 | Glycogen Synthase Kinase-3 Beta, Human | 2 |
| IKKB_HUMAN | O14920 | CHEMBL1991 | Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit, Human | 1 |