FA10_HUMAN - Coagulation Factor X, Human | ZINC Is Not Commercial - A database of commercially-available compounds

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	4,842	10	8	60
Binding ≤ 1μM	3,979	7	7	50

Reactome ID	Description	Species
REACT_1439	Common Pathway	Homo sapiens
REACT_1573	Extrinsic Pathway	Homo sapiens
REACT_1050	Gamma-carboxylation of protein precursors	Homo sapiens
REACT_326	Intrinsic Pathway	Homo sapiens
REACT_733	Removal of aminoterminal propeptides from gamma-carboxylated proteins	Homo sapiens
REACT_1906	Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
FA5_HUMAN	P12259	CHEMBL3618	Coagulation Factor V, Human	34
PROC_HUMAN	P04070	CHEMBL4444	Vitamin K-dependent Protein C, Human	11
THRB_HUMAN	P00734	CHEMBL204	Thrombin, Human	1333

Extrinsic Pathway

Uniprot	Swissprot	Chembl	Description	Number Shared
FA7_HUMAN	P08709	CHEMBL3991	Coagulation Factor VII, Human	130
FA9_HUMAN	P00740	CHEMBL2016	Coagulation Factor IX, Human	232
TF_HUMAN	P13726	CHEMBL4081	Coagulation Factor III, Human	102

Gamma-carboxylation of protein precursors

Uniprot	Swissprot	Chembl	Description	Number Shared
FA7_HUMAN	P08709	CHEMBL3991	Coagulation Factor VII, Human	130
FA9_HUMAN	P00740	CHEMBL2016	Coagulation Factor IX, Human	232
PROC_HUMAN	P04070	CHEMBL4444	Vitamin K-dependent Protein C, Human	11
THRB_HUMAN	P00734	CHEMBL204	Thrombin, Human	1333

Intrinsic Pathway

Uniprot	Swissprot	Chembl	Description	Number Shared
FA11_HUMAN	P03951	CHEMBL2820	Coagulation Factor XI, Human	16
FA12_HUMAN	P00748	CHEMBL2821	Coagulation Factor XII, Human	2
FA9_HUMAN	P00740	CHEMBL2016	Coagulation Factor IX, Human	232
KLKB1_HUMAN	P03952	CHEMBL2000	Plasma Kallikrein, Human	25
THRB_HUMAN	P00734	CHEMBL204	Thrombin, Human	1333

Removal of aminoterminal propeptides from gamma-carboxylated proteins

Uniprot	Swissprot	Chembl	Description	Number Shared
FA7_HUMAN	P08709	CHEMBL3991	Coagulation Factor VII, Human	130
FA9_HUMAN	P00740	CHEMBL2016	Coagulation Factor IX, Human	232
PROC_HUMAN	P04070	CHEMBL4444	Vitamin K-dependent Protein C, Human	11
THRB_HUMAN	P00734	CHEMBL204	Thrombin, Human	1333

Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu

Uniprot	Swissprot	Chembl	Description	Number Shared
FA7_HUMAN	P08709	CHEMBL3991	Coagulation Factor VII, Human	130
FA9_HUMAN	P00740	CHEMBL2016	Coagulation Factor IX, Human	232
PROC_HUMAN	P04070	CHEMBL4444	Vitamin K-dependent Protein C, Human	11
THRB_HUMAN	P00734	CHEMBL204	Thrombin, Human	1333

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
FA10_BOVIN	P00743	CHEMBL3656	Coagulation Factor X, Bovin	91	1	0	4
FA10_RABIT	O19045	CHEMBL5062	Coagulation Factor X, Rabit	16	2	2	2
FA10_RAT	Q63207	CHEMBL3755	Coagulation Factor X, Rat	13	0	0	0

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
FA11_HUMAN	P03951	CHEMBL2820	Coagulation Factor XI, Human	62	0	0	0
FA12_HUMAN	P00748	CHEMBL2821	Coagulation Factor XII, Human	8	1	0	0
FA5_HUMAN	P12259	CHEMBL3618	Coagulation Factor V, Human	40	6	0	0
FA7_HUMAN	P08709	CHEMBL3991	Coagulation Factor VII, Human	612	0	0	7
FA8_HUMAN	P00451	CHEMBL3143	Coagulation Factor VIII, Human	2	2	0	0
FA9_HUMAN	P00740	CHEMBL2016	Coagulation Factor IX, Human	255	0	1	5
FAAH1_HUMAN	O00519	CHEMBL2243	Anandamide Amidohydrolase, Human	624	36	12	3
FABP4_HUMAN	P15090	CHEMBL2083	Fatty Acid Binding Protein Adipocyte, Human	94	16	5	9
FABP5_HUMAN	Q01469	CHEMBL3674	Fatty Acid Binding Protein Epidermal, Human	19	6	2	3
FABPH_HUMAN	P05413	CHEMBL3344	Fatty Acid Binding Protein Muscle, Human	27	7	2	4
FABPI_HUMAN	P12104	CHEMBL4879	Fatty Acid Binding Protein Intestinal, Human	5	4	3	3
FABPL_HUMAN	P07148	CHEMBL5421	Fatty Acid-binding Protein, Liver, Human	3	2	1	1
FACE2_HUMAN	Q9Y256	CHEMBL3411	Prenyl Protein Specific Protease, Human	2	0	0	0
FADS1_HUMAN	O60427	CHEMBL5840	Fatty Acid Desaturase 1, Human	1	0	0	0
FAK1_HUMAN	Q05397	CHEMBL2695	Focal Adhesion Kinase 1, Human	160	15	6	8
FAK2_HUMAN	Q14289	CHEMBL5469	Protein Tyrosine Kinase 2 Beta, Human	57	11	4	5
FAS_HUMAN	P49327	CHEMBL4158	Fatty Acid Synthase, Human	42	3	5	1

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
FA10-1-E	Coagulation Factor X (cluster #1 Of 2), Eukaryotic	4,741	9	7	60
FA10-2-E	Coagulation Factor X (cluster #2 Of 2), Eukaryotic	214	2	1	6

Uniprot	Swissprot	Chembl	Description	Number Shared
THRB_HUMAN	P00734	CHEMBL204	Thrombin, Human	1325
TRY1_HUMAN	P07477	CHEMBL209	Trypsin I, Human	968
PLMN_HUMAN	P00747	CHEMBL1801	Plasminogen, Human	272
FA9_HUMAN	P00740	CHEMBL2016	Coagulation Factor IX, Human	232
UROK_HUMAN	P00749	CHEMBL3286	Urokinase-type Plasminogen Activator, Human	221
TRY2_HUMAN	P07478	CHEMBL3159	Trypsin II, Human	201
O77669_CANFA	O77669	CHEMBL3929	Coagulation Factor X, Canine	138
FA7_HUMAN	P08709	CHEMBL3991	Coagulation Factor VII, Human	130
TF_HUMAN	P13726	CHEMBL4081	Coagulation Factor III, Human	102
TPA_HUMAN	P00750	CHEMBL1873	Tissue-type Plasminogen Activator, Human	98
ST14_HUMAN	Q9Y5Y6	CHEMBL3018	Matriptase, Human	74
TRY1_BOVIN	P00760	CHEMBL3769	Trypsin I, Bovin	73
TRY2_BOVIN	Q29463	CHEMBL4472	Trypsin II, Bovin	60
FA5_HUMAN	P12259	CHEMBL3618	Coagulation Factor V, Human	34
FA10_BOVIN	P00743	CHEMBL3656	Coagulation Factor X, Bovin	27
TRY3_HUMAN	P35030	CHEMBL4551	Trypsin III, Human	27
KLKB1_HUMAN	P03952	CHEMBL2000	Plasma Kallikrein, Human	25
THRB_RAT	P18292	CHEMBL3078	Thrombin, Rat	19
PLMN_RAT	Q01177	CHEMBL3204	Plasminogen, Rat	18
TRY2_RAT	P00763	CHEMBL4290	Trypsin II, Rat	17
FA10_RABIT	O19045	CHEMBL5062	Coagulation Factor X, Rabit	16
FA11_HUMAN	P03951	CHEMBL2820	Coagulation Factor XI, Human	16
KLK1_HUMAN	P06870	CHEMBL2319	Kallikrein 1, Human	15
TM11D_HUMAN	O60235	CHEMBL1795138	Transmembrane Protease Serine 11D, Human	12
CTRB1_HUMAN	P17538	CHEMBL4796	Beta-chymotrypsin, Human	11
FA10_RAT	Q63207	CHEMBL3755	Coagulation Factor X, Rat	11
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	11
PROC_HUMAN	P04070	CHEMBL4444	Vitamin K-dependent Protein C, Human	11
KLK10_HUMAN	O43240	CHEMBL4180	Kallikrein 10, Human	8
KLK11_HUMAN	Q9UBX7	CHEMBL3031	Kallikrein 11, Human	8
KLK12_HUMAN	Q9UKR0	CHEMBL4943	Kallikrein 12, Human	8
KLK13_HUMAN	Q9UKR3	CHEMBL4863	Kallikrein 13, Human	8
KLK14_HUMAN	Q9P0G3	CHEMBL2641	Kallikrein 14, Human	8
KLK15_HUMAN	Q9H2R5	CHEMBL2174	Kallikrein 15, Human	8
KLK2_HUMAN	P20151	CHEMBL2442	Kallikrein 2, Human	8
KLK3_HUMAN	P07288	CHEMBL2099	Prostate Specific Antigen, Human	8
KLK4_HUMAN	Q9Y5K2	CHEMBL4446	Kallikrein 4, Human	8
KLK5_HUMAN	Q9Y337	CHEMBL4447	Kallikrein 5, Human	8
KLK6_HUMAN	Q92876	CHEMBL4448	Kallikrein 6, Human	8
KLK7_HUMAN	P49862	CHEMBL2443	Kallikrein 7, Human	8
KLK8_HUMAN	O60259	CHEMBL4812	Kallikrein 8, Human	8
KLK9_HUMAN	Q9UKQ9	CHEMBL3029	Kallikrein 9, Human	8
THRB_BOVIN	P00735	CHEMBL4471	Thrombin, Bovin	7
KPCA_HUMAN	P17252	CHEMBL299	Protein Kinase C Alpha, Human	5
KPCB_HUMAN	P05771	CHEMBL3045	Protein Kinase C Beta, Human	5
KPCD1_HUMAN	Q15139	CHEMBL3863	Protein Kinase C Mu, Human	5
KPCD3_HUMAN	O94806	CHEMBL2595	Protein Kinase C Nu, Human	5
KPCD_HUMAN	Q05655	CHEMBL2996	Protein Kinase C Delta, Human	5
KPCE_HUMAN	Q02156	CHEMBL3582	Protein Kinase C Epsilon, Human	5
KPCG_HUMAN	P05129	CHEMBL2938	Protein Kinase C Gamma, Human	5
KPCI_HUMAN	P41743	CHEMBL2598	Protein Kinase C Iota, Human	5
KPCL_HUMAN	P24723	CHEMBL3616	Protein Kinase C Eta, Human	5
KPCT_HUMAN	Q04759	CHEMBL3920	Protein Kinase C Theta, Human	5
KPCZ_HUMAN	Q05513	CHEMBL3438	Protein Kinase C Zeta, Human	5
ITA2B_HUMAN	P08514	CHEMBL212	Integrin Alpha-IIb, Human	4
APOH_HUMAN	P02749	CHEMBL2859	Apolipoprotein H, Human	3
TMPS2_HUMAN	O15393	CHEMBL1795140	Transmembrane Protease Serine 2, Human	3
FA12_HUMAN	P00748	CHEMBL2821	Coagulation Factor XII, Human	2
C1S_HUMAN	P09871	CHEMBL3913	Complement C1s, Human	1
CTRA_BOVIN	P00766	CHEMBL3314	Alpha-chymotrypsin, Bovin	1
ITB3_HUMAN	P05106	CHEMBL207	Integrin Beta-3, Human	1
TMPS6_HUMAN	Q8IU80	CHEMBL1795139	Transmembrane Protease Serine 6, Human	1
TRYB1_HUMAN	Q15661	CHEMBL2617	Tryptase Beta-1, Human	1
TRYG1_HUMAN	Q9NRR2	CHEMBL4955	Tryptase Gamma, Human	1