ZINC 12

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Swissprot:: FKB1A_HUMAN
Stitch:: FKB1A_HUMAN
UniProt:: P62942
ChEMBL:: CHEMBL1902
Reactome:: REACT_120850; REACT_120726; REACT_169263; REACT_169445; REACT_169440
PDB:: 1A7X (DOCK); 1B6C (DOCK); 1BKF (DOCK); 1BL4 (DOCK); 1D6O (DOCK); 1D7H (DOCK); 1D7I (DOCK); 1D7J (DOCK); 1EYM (DOCK); 1F40 (DOCK); 1FAP (DOCK); 1FKB (DOCK); 1FKD (DOCK); 1FKF (DOCK); 1FKG (DOCK); 1FKH (DOCK); 1FKI (DOCK); 1FKJ (DOCK); 1FKR (DOCK); 1FKS (DOCK); 1FKT (DOCK); 1J4H (DOCK); 1J4I (DOCK); 1J4R (DOCK); 1NSG (DOCK); 1QPF (DOCK); 1QPL (DOCK); 2DG3 (DOCK); 2DG4 (DOCK); 2DG9 (DOCK); 2FAP (DOCK); 2FKE (DOCK); 2PPN (DOCK); 2PPO (DOCK); 2PPP (DOCK); 3FAP (DOCK); 3H9R (DOCK); 3MDY (DOCK); 4FAP (DOCK); FKBP1A

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	470	22	1	3
Binding ≤ 1μM	358	3	0	2

Reactome ID	Description	Species
REACT_120850	TGF-beta receptor signaling activates SMADs	Homo sapiens
REACT_120726	TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Homo sapiens
REACT_169263	TGFBR1 KD Mutants in Cancer	Homo sapiens
REACT_169445	TGFBR1 LBD Mutants in Cancer	Homo sapiens
REACT_169440	TGFBR2 Kinase Domain Mutants in Cancer	Homo sapiens

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
FKB1A_RAT	Q62658	CHEMBL2095	FK506-binding Protein 1A, Rat	17	1	0	1

Uniprot	Swissprot	Chembl	Description	Number Shared
FKB1B_HUMAN	P68106	CHEMBL2430	FK506-binding Protein 1B, Human	27
Q8QGU2_CHICK	Q8QGU2	CHEMBL2301	FK506 Binding Protein 12, Chick	24
MTOR_HUMAN	P42345	CHEMBL2842	FK506 Binding Protein 12, Human	5
FKB14_HUMAN	Q9NWM8	CHEMBL2342	FK506 Binding Protein 14, Human	4
FKBP3_HUMAN	Q00688	CHEMBL4746	FK506 Binding Protein 3, Human	4
FKBP4_HUMAN	Q02790	CHEMBL4050	FK506 Binding Protein 4, Human	4
MIP_LEGPN	Q70YI1	CHEMBL1667669	Outer Membrane Protein MIP, Legpn	2
FKB1A_RAT	Q62658	CHEMBL2095	FK506-binding Protein 1A, Rat	1
RYR1_HUMAN	P21817	CHEMBL1846	Ryanodine Receptor 1, Human	1