ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (207)
Reactome (2)
Related By:
Pathway (11)
Organism (3)
Gene (5)
Org. Clust. (7)
ChEMBL (69)
Rings (15)

GABA Receptor Alpha-1 Subunit, Rat (207 Compounds)

Swissprot:: GBRA1_RAT
Stitch:: GBRA1_RAT
UniProt:: P62813
ChEMBL:: CHEMBL343
Reactome:: REACT_199021; REACT_199029
PDB:: Gabra1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	207	16	9	6
Binding ≤ 1μM	191	12	7	5
Functional ≤ 10μM	1	1	1	1

Reactome ID	Description	Species
REACT_199021	GABA A receptor activation	Rattus norvegicus
REACT_199029	Ligand-gated ion channel transport	Rattus norvegicus

Uniprot	Swissprot	Chembl	Description	Number Shared
GBRA4_RAT	P28471	CHEMBL292	GABA Receptor Alpha-4 Subunit, Rat	120
GBRA5_RAT	P19969	CHEMBL300	GABA Receptor Alpha-5 Subunit, Rat	162
GBRB2_RAT	P63138	CHEMBL295	GABA Receptor Beta-2 Subunit, Rat	138
GBRG2_RAT	P18508	CHEMBL297	GABA Receptor Gamma-2 Subunit, Rat	150
GBRG3_RAT	P28473	CHEMBL336	GABA Receptor Gamma-3 Subunit, Rat	80

Ligand-gated ion channel transport

Uniprot	Swissprot	Chembl	Description	Number Shared
GBRA4_RAT	P28471	CHEMBL292	GABA Receptor Alpha-4 Subunit, Rat	120
GBRA5_RAT	P19969	CHEMBL300	GABA Receptor Alpha-5 Subunit, Rat	162
GBRB2_RAT	P63138	CHEMBL295	GABA Receptor Beta-2 Subunit, Rat	138
GBRG2_RAT	P18508	CHEMBL297	GABA Receptor Gamma-2 Subunit, Rat	150
GBRG3_RAT	P28473	CHEMBL336	GABA Receptor Gamma-3 Subunit, Rat	80
GBRR2_RAT	P47742	CHEMBL2953	GABA Receptor Rho-2 Subunit, Rat	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
GBRA1_BOVIN	P08219	CHEMBL3627	GABA Receptor Alpha-1 Subunit, Bovin	302	43	17	5
GBRA1_HUMAN	P14867	CHEMBL1962	GABA Receptor Alpha-1 Subunit, Human	959	77	35	22
GBRA1_MOUSE	P62812	CHEMBL3139	GABA Receptor Alpha-1 Subunit, Mouse	45	6	5	2

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
GBRA2_RAT	P23576	CHEMBL341	GABA Receptor Alpha-2 Subunit, Rat	250	27	18	11
GBRA3_RAT	P20236	CHEMBL328	GABA Receptor Alpha-3 Subunit, Rat	159	12	11	7
GBRA4_RAT	P28471	CHEMBL292	GABA Receptor Alpha-4 Subunit, Rat	147	11	11	7
GBRA5_RAT	P19969	CHEMBL300	GABA Receptor Alpha-5 Subunit, Rat	189	15	11	7
GBRA6_RAT	P30191	CHEMBL293	GABA Receptor Alpha-6 Subunit, Rat	146	12	11	7

Clustered By Gene (0)

Clustered By Organism (7)

Code	Description	Substances	Purchasable	Natural	In Man
GBRA1-1-E	GABA Receptor Alpha-1 Subunit (cluster #1 Of 8), Eukaryotic	1,249	78	38	23
GBRA1-2-E	GABA Receptor Alpha-1 Subunit (cluster #2 Of 8), Eukaryotic	28	2	2	0
GBRA1-3-E	GABA Receptor Alpha-1 Subunit (cluster #3 Of 8), Eukaryotic	33	2	1	1
GBRA1-4-E	GABA Receptor Alpha-1 Subunit (cluster #4 Of 8), Eukaryotic	14	0	0	0
GBRA1-5-E	GABA Receptor Alpha-1 Subunit (cluster #5 Of 8), Eukaryotic	12	4	1	1
GBRA1-6-E	GABA Receptor Alpha-1 Subunit (cluster #6 Of 8), Eukaryotic	134	30	10	0
GBRA1-7-E	GABA Receptor Alpha-1 Subunit (cluster #7 Of 8), Eukaryotic	4	4	1	1
GBRA1-8-E	GABA Receptor Alpha-1 Subunit (cluster #8 Of 8), Eukaryotic	3	0	0	0

Uniprot	Swissprot	Chembl	Description	Number Shared
GBRA5_RAT	P19969	CHEMBL300	GABA Receptor Alpha-5 Subunit, Rat	162
GBRA2_RAT	P23576	CHEMBL341	GABA Receptor Alpha-2 Subunit, Rat	161
GBRG2_RAT	P18508	CHEMBL297	GABA Receptor Gamma-2 Subunit, Rat	150
GBRB2_RAT	P63138	CHEMBL295	GABA Receptor Beta-2 Subunit, Rat	138
GBRA3_RAT	P20236	CHEMBL328	GABA Receptor Alpha-3 Subunit, Rat	132
GBRA4_RAT	P28471	CHEMBL292	GABA Receptor Alpha-4 Subunit, Rat	120
GBRB3_RAT	P63079	CHEMBL316	GABA Receptor Beta-3 Subunit, Rat	119
GBRA6_RAT	P30191	CHEMBL293	GABA Receptor Alpha-6 Subunit, Rat	114
GBRG1_RAT	P23574	CHEMBL296	GABA Receptor Gamma-1 Subunit, Rat	82
GBRG3_RAT	P28473	CHEMBL336	GABA Receptor Gamma-3 Subunit, Rat	80
GBRB1_RAT	P15431	CHEMBL334	GABA Receptor Beta-1 Subunit, Rat	77
Q91ZM7_RAT	Q91ZM7	CHEMBL305	GABA Receptor Theta Subunit, Rat	77
GBRD_RAT	P18506	CHEMBL337	GABA Receptor Delta Subunit, Rat	74
GBRE_RAT	Q9ES14	CHEMBL306	GABA Receptor Epsilon Subunit, Rat	74
GBRR1_RAT	P50572	CHEMBL3588	GABA Receptor Rho-1 Subunit, Rat	68
GBRA1_BOVIN	P08219	CHEMBL3627	GABA Receptor Alpha-1 Subunit, Bovin	32
GBRA2_BOVIN	P10063	CHEMBL2321	GABA Receptor Alpha-2 Subunit, Bovin	32
GBRA3_BOVIN	P10064	CHEMBL3628	GABA Receptor Alpha-3 Subunit, Bovin	32
GBRA4_BOVIN	P20237	CHEMBL3140	GABA Receptor Alpha-4 Subunit, Bovin	32
GBRB1_BOVIN	P08220	CHEMBL2848	GABA Receptor Beta-1 Subunit, Bovin	32
GBRG2_BOVIN	P22300	CHEMBL5138	GABA Receptor Gamma-2 Subunit, Bovin	32
Z104301	Z104301	CHEMBL1907607	GABA-A Receptor; Anion Channel	19
GBRA1_HUMAN	P14867	CHEMBL1962	GABA Receptor Alpha-1 Subunit, Human	16
GBRA2_HUMAN	P47869	CHEMBL4956	GABA Receptor Alpha-2 Subunit, Human	14
GBRA3_HUMAN	P34903	CHEMBL3026	GABA Receptor Alpha-3 Subunit, Human	14
GBRG2_HUMAN	P18507	CHEMBL1788	GABA Receptor Gamma-2 Subunit, Human	14
GBRA5_HUMAN	P31644	CHEMBL5112	GABA Receptor Alpha-5 Subunit, Human	13
GBRB2_HUMAN	P47870	CHEMBL1920	GABA Receptor Beta-2 Subunit, Human	13
GBRB3_HUMAN	P28472	CHEMBL1847	GABA Receptor Beta-3 Subunit, Human	12
GBRA6_HUMAN	Q16445	CHEMBL2579	GABA Receptor Alpha-6 Subunit, Human	11
GBRP_RAT	O09028	CHEMBL294	GABA Receptor Pi Subunit, Rat	10
GBRA4_HUMAN	P48169	CHEMBL2472	GABA Receptor Alpha-4 Subunit, Human	9
GBRB1_HUMAN	P18505	CHEMBL4558	GABA Receptor Beta-1 Subunit, Human	8
GBRD_HUMAN	O14764	CHEMBL3591	GABA Receptor Delta Subunit, Human	8
GBRE_HUMAN	P78334	CHEMBL4635	GABA Receptor Epsilon Subunit, Human	8
GBRG1_HUMAN	Q8N1C3	CHEMBL4044	GABA Receptor Gamma-1 Subunit, Human	8
GBRG3_HUMAN	Q99928	CHEMBL2739	GABA Receptor Gamma-3 Subunit, Human	8
GBRP_HUMAN	O00591	CHEMBL3506	GABA Receptor Pi Subunit, Human	8
GBRT_HUMAN	Q9UN88	CHEMBL2843	GABA Receptor Theta Subunit, Human	8
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	4
AA1R_HUMAN	P30542	CHEMBL226	Adenosine A1 Receptor, Human	3
GBRA1_MOUSE	P62812	CHEMBL3139	GABA Receptor Alpha-1 Subunit, Mouse	2
TSPO_RAT	P16257	CHEMBL4552	Peripheral-type Benzodiazepine Receptor, Rat	2
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	2
A2AMW3_MOUSE	A2AMW3	CHEMBL3121	GABA Receptor Epsilon Subunit, Mouse	1
FABPL_RAT	P02692	CHEMBL5738	Fatty Acid-binding Protein, Liver, Rat	1
GABR1_HUMAN	Q9UBS5	CHEMBL2064	GABA-B Receptor 1, Human	1
GABR1_RAT	Q9Z0U4	CHEMBL2753	GABA-B Receptor 1, Rat	1
GABR2_HUMAN	O75899	CHEMBL5034	GABA-B Receptor 2, Human	1
GABR2_RAT	O88871	CHEMBL4686	GABA-B Receptor 2, Rat	1
GBRA2_MOUSE	P26048	CHEMBL2705	GABA Receptor Alpha-2 Subunit, Mouse	1
GBRA3_MOUSE	P26049	CHEMBL3387	GABA Receptor Alpha-3 Subunit, Mouse	1
GBRA4_MOUSE	Q9D6F4	CHEMBL4182	GABA Receptor Alpha-4 Subunit, Mouse	1
GBRA5_MOUSE	Q8BHJ7	CHEMBL2304	GABA Receptor Alpha-5 Subunit, Mouse	1
GBRA6_MOUSE	P16305	CHEMBL4710	GABA Receptor Alpha-6 Subunit, Mouse	1
GBRB1_MOUSE	P50571	CHEMBL2839	GABA Receptor Beta-1 Subunit, Mouse	1
GBRB3_MOUSE	P63080	CHEMBL4231	GABA Receptor Beta-3 Subunit, Mouse	1
GBRD_MOUSE	P22933	CHEMBL3907	GABA Receptor Delta Subunit, Mouse	1
GBRG1_MOUSE	Q9R0Y8	CHEMBL2891	GABA Receptor Gamma-1 Subunit, Mouse	1
GBRG2_MOUSE	P22723	CHEMBL2941	GABA Receptor Gamma-2 Subunit, Mouse	1
GBRG3_MOUSE	P27681	CHEMBL4236	GABA Receptor Gamma-3 Subunit, Mouse	1
GBRP_MOUSE	Q8QZW7	CHEMBL2746	GABA Receptor Pi Subunit, Mouse	1
GBRR2_RAT	P47742	CHEMBL2953	GABA Receptor Rho-2 Subunit, Rat	1
GBRT_MOUSE	Q9JLF1	CHEMBL3249	GABA Receptor Theta Subunit, Mouse	1
I23O1_HUMAN	P14902	CHEMBL4685	Indoleamine 2,3-dioxygenase, Human	1
S6A11_HUMAN	P48066	CHEMBL5208	GABA Transporter 3, Human	1
S6A13_RAT	P31646	CHEMBL4889	GABA Transporter 2, Rat	1
SC6A1_HUMAN	P30531	CHEMBL1903	GABA Transporter 1, Human	1
SC6A1_RAT	P23978	CHEMBL4054	GABA Transporter 1, Rat	1