ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (171)
Reactome (0)
Related By:
Pathway (0)
Organism (2)
Gene (7)
Org. Clust. (2)
ChEMBL (54)
Rings (35)

Metabotropic Glutamate Receptor 1, Rat (171 Compounds)

Swissprot:: GRM1_RAT
Stitch:: GRM1_RAT
UniProt:: P23385
ChEMBL:: CHEMBL4477
PDB:: 1EWK (DOCK); 1EWT (DOCK); 1EWV (DOCK); 1ISR (DOCK); 1ISS (DOCK); Grm1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	171	17	4	3
Binding ≤ 1μM	142	11	1	1
Functional ≤ 10μM	219	29	7	4

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
GRM1_HUMAN	Q13255	CHEMBL3772	Metabotropic Glutamate Receptor 1, Human	51	12	6	4
GRM1_MOUSE	P97772	CHEMBL2892	Metabotropic Glutamate Receptor 1, Mouse	6	3	1	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
GRM2_RAT	P31421	CHEMBL2851	Metabotropic Glutamate Receptor 2, Rat	484	18	6	3
GRM3_RAT	P31422	CHEMBL3067	Metabotropic Glutamate Receptor 3, Rat	222	14	7	3
GRM4_RAT	P31423	CHEMBL2787	Metabotropic Glutamate Receptor 4, Rat	55	19	2	2
GRM5_RAT	P31424	CHEMBL2564	Metabotropic Glutamate Receptor 5, Rat	557	61	5	4
GRM6_RAT	P35349	CHEMBL3842	Metabotropic Glutamate Receptor 6, Rat	8	5	2	2
GRM7_RAT	P35400	CHEMBL3879	Metabotropic Glutamate Receptor 7, Rat	5	2	0	0
GRM8_RAT	P70579	CHEMBL2718	Metabotropic Glutamate Receptor 8, Rat	6	3	1	1

Clustered By Gene (0)

Clustered By Organism (2)

Code	Description	Substances	Purchasable	Natural	In Man
GRM1-1-E	Metabotropic Glutamate Receptor 1 (cluster #1 Of 3), Eukaryotic	178	18	1	0
GRM1-2-E	Metabotropic Glutamate Receptor 1 (cluster #2 Of 3), Eukaryotic	9	5	2	1
GRM1-3-E	Metabotropic Glutamate Receptor 1 (cluster #3 Of 3), Eukaryotic	9	3	3	3

Uniprot	Swissprot	Chembl	Description	Number Shared
GRM1_HUMAN	Q13255	CHEMBL3772	Metabotropic Glutamate Receptor 1, Human	93
GRM5_RAT	P31424	CHEMBL2564	Metabotropic Glutamate Receptor 5, Rat	26
GRM2_RAT	P31421	CHEMBL2851	Metabotropic Glutamate Receptor 2, Rat	10
GRM3_RAT	P31422	CHEMBL3067	Metabotropic Glutamate Receptor 3, Rat	10
GRM5_HUMAN	P41594	CHEMBL3227	Metabotropic Glutamate Receptor 5, Human	7
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	6
GRIK3_RAT	P42264	CHEMBL3744	Glutamate Receptor Ionotropic Kainate 3, Rat	5
GRM2_HUMAN	Q14416	CHEMBL5137	Metabotropic Glutamate Receptor 2, Human	5
GRIK1_RAT	P22756	CHEMBL2919	Glutamate Receptor Ionotropic Kainate 1, Rat	4
GRIK2_RAT	P42260	CHEMBL3607	Glutamate Receptor Ionotropic Kainate 2, Rat	4
GRM4_RAT	P31423	CHEMBL2787	Metabotropic Glutamate Receptor 4, Rat	4
GRM6_RAT	P35349	CHEMBL3842	Metabotropic Glutamate Receptor 6, Rat	4
GRM8_RAT	P70579	CHEMBL2718	Metabotropic Glutamate Receptor 8, Rat	4
GRIA1_MOUSE	P23818	CHEMBL3502	Glutamate Receptor Ionotropic, AMPA 1, Mouse	3
GRIA2_RAT	P19491	CHEMBL3503	Glutamate Receptor Ionotropic, AMPA 2, Rat	3
GRIA3_RAT	P19492	CHEMBL3504	Glutamate Receptor Ionotropic, AMPA 3, Rat	3
GRIA4_RAT	P19493	CHEMBL3505	Glutamate Receptor Ionotropic, AMPA 4, Rat	3
GRIK4_RAT	Q01812	CHEMBL3044	Glutamate Receptor Ionotropic Kainate 4, Rat	3
GRIK5_RAT	Q63273	CHEMBL4041	Glutamate Receptor Ionotropic Kainate 5, Rat	3
GRM7_RAT	P35400	CHEMBL3879	Metabotropic Glutamate Receptor 7, Rat	3
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA Receptor	3
GRIA1_HUMAN	P42261	CHEMBL2009	Glutamate Receptor Ionotropic, AMPA 1, Human	2
GRIA1_RAT	P19490	CHEMBL3753	Glutamate Receptor Ionotropic, AMPA 1, Rat	2
GRIA2_HUMAN	P42262	CHEMBL4016	Glutamate Receptor Ionotropic, AMPA 2, Human	2
GRIA4_HUMAN	P48058	CHEMBL3190	Glutamate Receptor Ionotropic, AMPA 4, Human	2
GRIK1_HUMAN	P39086	CHEMBL1918	Glutamate Receptor Ionotropic Kainate 1, Human	2
GRIK2_HUMAN	Q13002	CHEMBL3683	Glutamate Receptor Ionotropic Kainate 2, Human	2
GRIK3_HUMAN	Q13003	CHEMBL3684	Glutamate Receptor Ionotropic Kainate 3, Human	2
GRIK5_HUMAN	Q16478	CHEMBL2675	Glutamate Receptor Ionotropic Kainate 5, Human	2
GRM3_HUMAN	Q14832	CHEMBL2888	Metabotropic Glutamate Receptor 3, Human	2
GRM4_HUMAN	Q14833	CHEMBL2736	Metabotropic Glutamate Receptor 4, Human	2
GRM8_MOUSE	P47743	CHEMBL4626	Metabotropic Glutamate Receptor 8, Mouse	2
NMDE1_RAT	Q00959	CHEMBL310	Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat	2
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	1
EAA3_HUMAN	P43005	CHEMBL2721	Excitatory Amino Acid Transporter 3, Human	1
FOLH1_HUMAN	Q04609	CHEMBL1892	Glutamate Carboxypeptidase II, Human	1
GRIA2_MOUSE	P23819	CHEMBL3205	Glutamate Receptor Ionotropic, AMPA 2, Mouse	1
GRIA3_HUMAN	P42263	CHEMBL3595	Glutamate Receptor Ionotropic, AMPA 3, Human	1
GRIA3_MOUSE	Q9Z2W9	CHEMBL3624	Glutamate Receptor Ionotropic, AMPA 3, Mouse	1
GRIA4_MOUSE	Q9Z2W8	CHEMBL3615	Glutamate Receptor Ionotropic, AMPA 4, Mouse	1
GRM1_MOUSE	P97772	CHEMBL2892	Metabotropic Glutamate Receptor 1, Mouse	1
GRM3_MOUSE	Q9QYS2	CHEMBL3824	Metabotropic Glutamate Receptor 3, Mouse	1
GRM6_HUMAN	O15303	CHEMBL4573	Metabotropic Glutamate Receptor 6, Human	1
GRM7_MOUSE	Q68ED2	CHEMBL3966	Metabotropic Glutamate Receptor 7, Mouse	1
GRM8_HUMAN	O00222	CHEMBL3228	Metabotropic Glutamate Receptor 8, Human	1
MURI_HELPY	P56068	CHEMBL6078	Glutamate Racemase, Helpy	1
NMDE2_RAT	Q00960	CHEMBL311	Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat	1
NMDE3_RAT	Q00961	CHEMBL401	Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat	1
NMDE4_RAT	Q62645	CHEMBL303	Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat	1
NMDZ1_RAT	P35439	CHEMBL330	Glutamate (NMDA) Receptor Subunit Zeta 1, Rat	1
Q80T35_MOUSE	Q80T35	CHEMBL3033	Metabotropic Glutamate Receptor 6, Mouse	1
Q80T43_MOUSE	Q80T43	CHEMBL3779	Metabotropic Glutamate Receptor 2, Mouse	1
Q80T47_MOUSE	Q80T47	CHEMBL2832	Metabotropic Glutamate Receptor 5, Mouse	1
XCT_HUMAN	Q9UPY5	CHEMBL1075149	Cystine/glutamate Transporter, Human	1