UCSF

Metabotropic Glutamate Receptor 2, Rat (484 Compounds)

Swissprot:
GRM2_RAT
Stitch:
GRM2_RAT
UniProt:
P31421
ChEMBL:
CHEMBL2851
Reactome:
REACT_236177
REACT_233455
PDB:
Grm2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 484 18 6 3
Binding ≤ 1μM 385 8 4 1
Functional ≤ 10μM 111 8 4 2

Reactome Network (2)

Reactome ID Description Species
REACT_236177 Class C/3 (Metabotropic glutamate/pheromone receptors) Rattus norvegicus
REACT_233455 G alpha (i) signalling events Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
GRM3_RAT P31422 CHEMBL3067 Metabotropic Glutamate Receptor 3, Rat 230
GRM4_RAT P31423 CHEMBL2787 Metabotropic Glutamate Receptor 4, Rat 8
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 10
GRM6_RAT P35349 CHEMBL3842 Metabotropic Glutamate Receptor 6, Rat 10

G alpha (i) signalling events

Uniprot Swissprot Chembl Description Number Shared
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 13
GRM3_RAT P31422 CHEMBL3067 Metabotropic Glutamate Receptor 3, Rat 230
GRM4_RAT P31423 CHEMBL2787 Metabotropic Glutamate Receptor 4, Rat 8
GRM6_RAT P35349 CHEMBL3842 Metabotropic Glutamate Receptor 6, Rat 10
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GRM2_HUMAN Q14416 CHEMBL5137 Metabotropic Glutamate Receptor 2, Human 293 14 4 3
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GRM1_RAT P23385 CHEMBL4477 Metabotropic Glutamate Receptor 1, Rat 171 17 4 3
GRM3_RAT P31422 CHEMBL3067 Metabotropic Glutamate Receptor 3, Rat 222 14 7 3
GRM4_RAT P31423 CHEMBL2787 Metabotropic Glutamate Receptor 4, Rat 55 19 2 2
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 557 61 5 4
GRM6_RAT P35349 CHEMBL3842 Metabotropic Glutamate Receptor 6, Rat 8 5 2 2
GRM7_RAT P35400 CHEMBL3879 Metabotropic Glutamate Receptor 7, Rat 5 2 0 0
GRM8_RAT P70579 CHEMBL2718 Metabotropic Glutamate Receptor 8, Rat 6 3 1 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
GRM2-1-E Metabotropic Glutamate Receptor 2 (cluster #1 Of 2), Eukaryotic 432 21 6 3
GRM2-2-E Metabotropic Glutamate Receptor 2 (cluster #2 Of 2), Eukaryotic 337 4 0 0
Uniprot Swissprot Chembl Description Number Shared
GRM3_RAT P31422 CHEMBL3067 Metabotropic Glutamate Receptor 3, Rat 230
GRM2_HUMAN Q14416 CHEMBL5137 Metabotropic Glutamate Receptor 2, Human 26
GRM8_HUMAN O00222 CHEMBL3228 Metabotropic Glutamate Receptor 8, Human 15
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 13
GRM1_RAT P23385 CHEMBL4477 Metabotropic Glutamate Receptor 1, Rat 10
GRM3_HUMAN Q14832 CHEMBL2888 Metabotropic Glutamate Receptor 3, Human 9
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 9
GRM6_RAT P35349 CHEMBL3842 Metabotropic Glutamate Receptor 6, Rat 9
GRM7_HUMAN Q14831 CHEMBL3777 Metabotropic Glutamate Receptor 7, Human 9
GRM4_RAT P31423 CHEMBL2787 Metabotropic Glutamate Receptor 4, Rat 8
GRM8_RAT P70579 CHEMBL2718 Metabotropic Glutamate Receptor 8, Rat 8
GRIK3_RAT P42264 CHEMBL3744 Glutamate Receptor Ionotropic Kainate 3, Rat 6
GRM1_HUMAN Q13255 CHEMBL3772 Metabotropic Glutamate Receptor 1, Human 6
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 6
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 5
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 4
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 4
GRM4_HUMAN Q14833 CHEMBL2736 Metabotropic Glutamate Receptor 4, Human 4
GRM7_RAT P35400 CHEMBL3879 Metabotropic Glutamate Receptor 7, Rat 4
GRIK1_RAT P22756 CHEMBL2919 Glutamate Receptor Ionotropic Kainate 1, Rat 3
GRIK2_RAT P42260 CHEMBL3607 Glutamate Receptor Ionotropic Kainate 2, Rat 3
GRIK4_RAT Q01812 CHEMBL3044 Glutamate Receptor Ionotropic Kainate 4, Rat 3
GRIK5_RAT Q63273 CHEMBL4041 Glutamate Receptor Ionotropic Kainate 5, Rat 3
GRM6_HUMAN O15303 CHEMBL4573 Metabotropic Glutamate Receptor 6, Human 3
GRIA1_HUMAN P42261 CHEMBL2009 Glutamate Receptor Ionotropic, AMPA 1, Human 2
GRIA1_MOUSE P23818 CHEMBL3502 Glutamate Receptor Ionotropic, AMPA 1, Mouse 2
GRIA2_HUMAN P42262 CHEMBL4016 Glutamate Receptor Ionotropic, AMPA 2, Human 2
GRIA2_RAT P19491 CHEMBL3503 Glutamate Receptor Ionotropic, AMPA 2, Rat 2
GRIA3_RAT P19492 CHEMBL3504 Glutamate Receptor Ionotropic, AMPA 3, Rat 2
GRIA4_HUMAN P48058 CHEMBL3190 Glutamate Receptor Ionotropic, AMPA 4, Human 2
GRIA4_RAT P19493 CHEMBL3505 Glutamate Receptor Ionotropic, AMPA 4, Rat 2
GRIK1_HUMAN P39086 CHEMBL1918 Glutamate Receptor Ionotropic Kainate 1, Human 2
GRIK2_HUMAN Q13002 CHEMBL3683 Glutamate Receptor Ionotropic Kainate 2, Human 2
GRIK3_HUMAN Q13003 CHEMBL3684 Glutamate Receptor Ionotropic Kainate 3, Human 2
GRIK5_HUMAN Q16478 CHEMBL2675 Glutamate Receptor Ionotropic Kainate 5, Human 2
NMDE1_RAT Q00959 CHEMBL310 Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat 2
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 2
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 1
EAA3_HUMAN P43005 CHEMBL2721 Excitatory Amino Acid Transporter 3, Human 1
GRIA1_RAT P19490 CHEMBL3753 Glutamate Receptor Ionotropic, AMPA 1, Rat 1
GRIA3_HUMAN P42263 CHEMBL3595 Glutamate Receptor Ionotropic, AMPA 3, Human 1
GRM8_MOUSE P47743 CHEMBL4626 Metabotropic Glutamate Receptor 8, Mouse 1
MURI_HELPY P56068 CHEMBL6078 Glutamate Racemase, Helpy 1
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 1
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 1
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 1
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 1

Most Common Rings