UCSF

Glycogen Synthase Kinase-3 Beta, Human (1,367 Compounds)

Swissprot:
GSK3B_HUMAN
Stitch:
GSK3B_HUMAN
UniProt:
P49841
ChEMBL:
CHEMBL262
Reactome:
REACT_12564
REACT_228196
REACT_228285
REACT_11065
REACT_147727
REACT_19199
REACT_11063
REACT_200610
REACT_228314
REACT_200780
REACT_228159
REACT_228251
REACT_228137
REACT_228261
REACT_228060
PDB:
1GNG (DOCK)
1H8F (DOCK)
1I09 (DOCK)
1J1B (DOCK)
1J1C (DOCK)
1O9U (DOCK)
1PYX (DOCK)
1Q3D (DOCK)
1Q3W (DOCK)
1Q41 (DOCK)
1Q4L (DOCK)
1Q5K (DOCK)
1R0E (DOCK)
1UV5 (DOCK)
2JDO (DOCK)
2JDR (DOCK)
2JLD (DOCK)
2O5K (DOCK)
2OW3 (DOCK)
2UW9 (DOCK)
2X39 (DOCK)
2XH5 (DOCK)
3CQU (DOCK)
3CQW (DOCK)
3DU8 (DOCK)
3E87 (DOCK)
3E88 (DOCK)
3E8D (DOCK)
3F7Z (DOCK)
3F88 (DOCK)
3GB2 (DOCK)
3I4B (DOCK)
3L1S (DOCK)
3M1S (DOCK)
3PUP (DOCK)
3Q3B (DOCK)
3SD0 (DOCK)
3ZRK (DOCK)
3ZRL (DOCK)
3ZRM (DOCK)
GSK3B

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1,367 166 28 48
Binding ≤ 1μM 1,038 107 15 37
Functional ≤ 10μM 40 2 0 0

Reactome Network (15)

Reactome ID Description Species
REACT_12564 AKT phosphorylates targets in the cytosol Homo sapiens
REACT_228196 APC truncation mutants have impaired AXIN binding Homo sapiens
REACT_228285 AXIN missense mutants destabilize the destruction complex Homo sapiens
REACT_11065 Beta-catenin phosphorylation cascade Homo sapiens
REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Homo sapiens
REACT_19199 CRMPs in Sema3A signaling Homo sapiens
REACT_11063 Degradation of beta-catenin by the destruction complex Homo sapiens
REACT_200610 disassembly of the destruction complex and recruitment of AXIN to the membrane Homo sapiens
REACT_228314 misspliced GSK3beta mutants stabilize beta-catenin Homo sapiens
REACT_200780 Regulation of HSF1-mediated heat shock response Homo sapiens
REACT_228159 S33 mutants of beta-catenin aren't phosphorylated Homo sapiens
REACT_228251 S37 mutants of beta-catenin aren't phosphorylated Homo sapiens
REACT_228137 S45 mutants of beta-catenin aren't phosphorylated Homo sapiens
REACT_228261 T41 mutants of beta-catenin aren't phosphorylated Homo sapiens
REACT_228060 truncations of AMER1 destabilize the destruction complex Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 36
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 43
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 24
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 345
IKKA_HUMAN O15111 CHEMBL3476 Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, Human 5

APC truncation mutants have impaired AXIN binding

Uniprot Swissprot Chembl Description Number Shared
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 9

AXIN missense mutants destabilize the destruction complex

Uniprot Swissprot Chembl Description Number Shared
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 9

Beta-catenin phosphorylation cascade

Uniprot Swissprot Chembl Description Number Shared
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 9

Constitutive PI3K/AKT Signaling in Cancer

Uniprot Swissprot Chembl Description Number Shared
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 36
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 43
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 24
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 23
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 3
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 3
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 3
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 345
IKKA_HUMAN O15111 CHEMBL3476 Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, Human 5
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 9
KS6B2_HUMAN Q9UBS0 CHEMBL3111 Ribosomal Protein S6 Kinase 2, Human 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 12
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 2
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 2
P85B_HUMAN O00459 CHEMBL4437 PI3-kinase P85-beta Subunit, Human 1
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 6
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 9
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 12
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 2
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 2
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 2

CRMPs in Sema3A signaling

Uniprot Swissprot Chembl Description Number Shared
CD5R1_HUMAN Q15078 CHEMBL2783 Cyclin-dependent Kinase 5 Regulatory Subunit 1, Human 3
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 18
FES_HUMAN P07332 CHEMBL5455 Tyrosine-protein Kinase FES, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 3

Degradation of beta-catenin by the destruction complex

Uniprot Swissprot Chembl Description Number Shared
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 9

disassembly of the destruction complex and recruitment of AXIN to the membrane

Uniprot Swissprot Chembl Description Number Shared
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 9
KC1G2_HUMAN P78368 CHEMBL2543 Casein Kinase I Gamma 2, Human 8

misspliced GSK3beta mutants stabilize beta-catenin

Uniprot Swissprot Chembl Description Number Shared
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 9

Regulation of HSF1-mediated heat shock response

Uniprot Swissprot Chembl Description Number Shared
MAPK2_HUMAN P49137 CHEMBL2208 MAP Kinase-activated Protein Kinase 2, Human 9
MK01_HUMAN P28482 CHEMBL4040 MAP Kinase ERK2, Human 15
MK03_HUMAN P27361 CHEMBL3385 MAP Kinase ERK1, Human 1
SIRT1_HUMAN Q96EB6 CHEMBL4506 NAD-dependent Deacetylase Sirtuin 1, Human 2

S33 mutants of beta-catenin aren't phosphorylated

Uniprot Swissprot Chembl Description Number Shared
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 9

S37 mutants of beta-catenin aren't phosphorylated

Uniprot Swissprot Chembl Description Number Shared
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 9

S45 mutants of beta-catenin aren't phosphorylated

Uniprot Swissprot Chembl Description Number Shared
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 9

T41 mutants of beta-catenin aren't phosphorylated

Uniprot Swissprot Chembl Description Number Shared
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 9

truncations of AMER1 destabilize the destruction complex

Uniprot Swissprot Chembl Description Number Shared
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 9
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GSK3B_MOUSE Q9WV60 CHEMBL1075321 Glycogen Synthase Kinase-3 Beta, Mouse 1 1 0 0
GSK3B_RAT P18266 CHEMBL3669 Glycogen Synthase Kinase-3 Beta, Rat 6 0 0 0

Clustered By Gene (0)

Clustered By Organism (6)

Code Description Substances Purchasable Natural In Man
GSK3B-1-E Glycogen Synthase Kinase-3 Beta (cluster #1 Of 7), Eukaryotic 1,121 117 13 36
GSK3B-2-E Glycogen Synthase Kinase-3 Beta (cluster #2 Of 7), Eukaryotic 21 14 3 0
GSK3B-3-E Glycogen Synthase Kinase-3 Beta (cluster #3 Of 7), Eukaryotic 17 13 2 0
GSK3B-4-E Glycogen Synthase Kinase-3 Beta (cluster #4 Of 7), Eukaryotic 126 4 1 5
GSK3B-5-E Glycogen Synthase Kinase-3 Beta (cluster #5 Of 7), Eukaryotic 29 2 0 0
GSK3B-6-E Glycogen Synthase Kinase-3 Beta (cluster #6 Of 7), Eukaryotic 17 7 0 0
GSK3B-7-E Glycogen Synthase Kinase-3 Beta (cluster #7 Of 7), Eukaryotic 38 10 9 8
Uniprot Swissprot Chembl Description Number Shared
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 345
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 164
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 149
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 114
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 114
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 98
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 96
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 65
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 62
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 62
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 51
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 49
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 43
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 42
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 42
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 40
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 36
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 30
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 30
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 27
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 27
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 26
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 25
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 24
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 23
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 23
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 23
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 21
KS6B1_HUMAN P23443 CHEMBL4501 Ribosomal Protein S6 Kinase 1, Human 21
VGFR2_MOUSE P35918 CHEMBL3337 Vascular Endothelial Growth Factor Receptor 2, Mouse 21
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 19
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 18
CDK9_HUMAN P50750 CHEMBL3116 Cyclin-dependent Kinase 9, Human 16
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 16
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 15
MK01_HUMAN P28482 CHEMBL4040 MAP Kinase ERK2, Human 15
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 15
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 13
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 13
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 13
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 13
MK09_HUMAN P45984 CHEMBL4179 C-Jun N-terminal Kinase 2, Human 13
MK10_HUMAN P53779 CHEMBL2637 C-Jun N-terminal Kinase 3, Human 13
CLK1_HUMAN P49759 CHEMBL4224 Dual Specificty Protein Kinase CLK1, Human 12
E2AK2_HUMAN P19525 CHEMBL5785 Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human 12
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 12
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 12
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 12
MK08_HUMAN P45983 CHEMBL2276 C-Jun N-terminal Kinase 1, Human 12
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 12
CCNB_MARGL P15206 CHEMBL4260 G2/mitotic-specific Cyclin B, Margl 11
KS6A1_HUMAN Q15418 CHEMBL2553 Ribosomal Protein S6 Kinase Alpha 1, Human 11
KS6A3_HUMAN P51812 CHEMBL2345 Ribosomal Protein S6 Kinase Alpha 3, Human 11
VGFR1_MOUSE P35969 CHEMBL3516 Vascular Endothelial Growth Factor Receptor 1, Mouse 11
CDK6_HUMAN Q00534 CHEMBL2508 Cyclin-dependent Kinase 6, Human 10
CDK7_HUMAN P50613 CHEMBL3055 Cyclin-dependent Kinase 7, Human 10
CHK1_HUMAN O14757 CHEMBL4630 Serine/threonine-protein Kinase Chk1, Human 10
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 10
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 10
KPCE_RAT P09216 CHEMBL3424 Protein Kinase C Epsilon, Rat 10
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 10
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 10
KS6A5_HUMAN O75582 CHEMBL4237 Ribosomal Protein S6 Kinase Alpha 5, Human 10
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 10
Z81135 Z81135 CHEMBL614793 L6 (Skeletal Muscle Myoblast Cells) 10
AURKC_HUMAN Q9UQB9 CHEMBL3935 Serine/threonine-protein Kinase Aurora-C, Human 9
GAK_HUMAN O14976 CHEMBL4355 Serine/threonine-protein Kinase GAK, Human 9
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 9
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 9
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 9
KPCG_RAT P63319 CHEMBL3604 Protein Kinase C Gamma, Rat 9
MAPK2_HUMAN P49137 CHEMBL2208 MAP Kinase-activated Protein Kinase 2, Human 9
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 9
PDK1_HUMAN Q15118 CHEMBL4766 Pyruvate Dehydrogenase Kinase Isoform 1, Human 9
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 9
CDK16_HUMAN Q00536 CHEMBL4597 Serine/threonine-protein Kinase PCTAIRE-1, Human 8
CLK2_HUMAN P49760 CHEMBL4225 Dual Specificity Protein Kinase CLK2, Human 8
GYS1_HUMAN P13807 CHEMBL4000 Muscle Glycogen Synthase, Human 8
KC1G1_HUMAN Q9HCP0 CHEMBL2426 Casein Kinase I Gamma 1, Human 8
KC1G2_HUMAN P78368 CHEMBL2543 Casein Kinase I Gamma 2, Human 8
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 8
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 8
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 8
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 7
CDK17_HUMAN Q00537 CHEMBL5790 Serine/threonine-protein Kinase PCTAIRE-2, Human 7
CDK3_HUMAN Q00526 CHEMBL4442 Cyclin-dependent Kinase 3, Human 7
CLK4_HUMAN Q9HAZ1 CHEMBL4203 Dual Specificity Protein Kinase CLK4, Human 7
CSF1R_HUMAN P07333 CHEMBL1844 Macrophage Colony Stimulating Factor Receptor, Human 7
CSK22_HUMAN P19784 CHEMBL4070 Casein Kinase II Alpha (prime), Human 7
CTRO_HUMAN O14578 CHEMBL5579 Citron Rho-interacting Kinase, Human 7
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 7
KGP1_HUMAN Q13976 CHEMBL4273 CGMP-dependent Protein Kinase 1 Beta, Human 7
KGP2_HUMAN Q13237 CHEMBL2896 CGMP-dependent Protein Kinase 2, Human 7
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 7
KS6A2_HUMAN Q15349 CHEMBL3906 Ribosomal Protein S6 Kinase Alpha 2, Human 7
KS6A4_HUMAN O75676 CHEMBL3125 Ribosomal Protein S6 Kinase Alpha 4, Human 7
KS6A6_HUMAN Q9UK32 CHEMBL4924 Ribosomal Protein S6 Kinase Alpha 6, Human 7
KSYK_HUMAN P43405 CHEMBL2599 Tyrosine-protein Kinase SYK, Human 7
MK15_HUMAN Q8TD08 CHEMBL5198 Mitogen-activated Protein Kinase 15, Human 7
SLK_HUMAN Q9H2G2 CHEMBL4202 Serine/threonine-protein Kinase 2, Human 7
TGFR2_HUMAN P37173 CHEMBL4267 TGF-beta Receptor Type II, Human 7
TTK_HUMAN P33981 CHEMBL3983 Dual Specificity Protein Kinase TTK, Human 7
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 7
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 7
ALK_HUMAN Q9UM73 CHEMBL4247 ALK Tyrosine Kinase Receptor, Human 6
CDC7_HUMAN O00311 CHEMBL5443 Cell Division Cycle 7-related Protein Kinase, Human 6
CDK18_HUMAN Q07002 CHEMBL5316 Serine/threonine-protein Kinase PCTAIRE-3, Human 6
CDK1_MOUSE P11440 CHEMBL4084 Cyclin-dependent Kinase 1, Mouse 6
CHK2_HUMAN O96017 CHEMBL2527 Serine/threonine-protein Kinase Chk2, Human 6
CSK2B_HUMAN P67870 CHEMBL2358 Casein Kinase II Beta, Human 6
DAPK3_HUMAN O43293 CHEMBL2468 Death-associated Protein Kinase 3, Human 6
DYR1B_HUMAN Q9Y463 CHEMBL5543 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human 6
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 6
GSK3B_RAT P18266 CHEMBL3669 Glycogen Synthase Kinase-3 Beta, Rat 6
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 6
KCC2A_HUMAN Q9UQM7 CHEMBL4147 CaM Kinase II Alpha, Human 6
KCC2B_HUMAN Q13554 CHEMBL4121 CaM Kinase II Beta, Human 6
KPCD3_HUMAN O94806 CHEMBL2595 Protein Kinase C Nu, Human 6
M3K9_HUMAN P80192 CHEMBL2872 Mitogen-activated Protein Kinase Kinase Kinase 9, Human 6
MK07_HUMAN Q13164 CHEMBL5332 Mitogen-activated Protein Kinase 7, Human 6
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 6
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 6
MP2K2_HUMAN P36507 CHEMBL2964 Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human 6
NUAK2_HUMAN Q9H093 CHEMBL5698 NUAK Family SNF1-like Kinase 2, Human 6
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 6
PGFRA_RAT P20786 CHEMBL2513 Platelet-derived Growth Factor Receptor Alpha, Rat 6
PHKG1_HUMAN Q16816 CHEMBL4004 Phosphorylase Kinase Gamma Subunit 1, Human 6
STK3_HUMAN Q13188 CHEMBL4708 Serine/threonine-protein Kinase MST2, Human 6
TNIK_HUMAN Q9UKE5 CHEMBL4527 TRAF2- And NCK-interacting Kinase, Human 6
XDH_HUMAN P47989 CHEMBL1929 Xanthine Dehydrogenase, Human 6
AAK1_HUMAN Q2M2I8 CHEMBL3830 Adaptor-associated Kinase, Human 5
ABCG2_HUMAN Q9UNQ0 CHEMBL5393 ATP-binding Cassette Sub-family G Member 2, Human 5
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 5
CCNT1_HUMAN O60563 CHEMBL2108 Cyclin T1, Human 5
CLK3_HUMAN P49761 CHEMBL4226 Dual Specificity Protein Kinase CLK3, Human 5
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1, Human 5
DCLK3_HUMAN Q9C098 CHEMBL6123 Serine/threonine-protein Kinase DCLK3, Human 5
DDR1_HUMAN Q08345 CHEMBL5319 Epithelial Discoidin Domain-containing Receptor 1, Human 5
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 5
FRK_HUMAN P42685 CHEMBL4223 Tyrosine-protein Kinase FRK, Human 5
IKKA_HUMAN O15111 CHEMBL3476 Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, Human 5
IKKB_HUMAN O14920 CHEMBL1991 Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit, Human 5
IRAK4_HUMAN Q9NWZ3 CHEMBL3778 Interleukin-1 Receptor-associated Kinase 4, Human 5
KCC2A_MOUSE P11798 CHEMBL3347 CaM Kinase II Alpha, Mouse 5
KCC2B_MOUSE P28652 CHEMBL4735 CaM Kinase II Beta, Mouse 5
KCC2D_HUMAN Q13557 CHEMBL2801 CaM Kinase II Delta, Human 5
KCC2G_HUMAN Q13555 CHEMBL3829 CaM Kinase II Gamma, Human 5
KCC2G_MOUSE Q923T9 CHEMBL4456 CaM Kinase II Gamma, Mouse 5
KKCC1_HUMAN Q8N5S9 CHEMBL5256 CaM-kinase Kinase Alpha, Human 5
KPCD2_HUMAN Q9BZL6 CHEMBL4900 Serine/threonine-protein Kinase D2, Human 5
KPCI_HUMAN P41743 CHEMBL2598 Protein Kinase C Iota, Human 5
M3K11_HUMAN Q16584 CHEMBL2708 Mitogen-activated Protein Kinase Kinase Kinase 11, Human 5
M4K1_HUMAN Q92918 CHEMBL5749 Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human 5
M4K3_HUMAN Q8IVH8 CHEMBL5432 Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human 5
MERTK_HUMAN Q12866 CHEMBL5331 Proto-oncogene Tyrosine-protein Kinase MER, Human 5
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 5
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 5
MRCKB_HUMAN Q9Y5S2 CHEMBL5052 Serine/threonine-protein Kinase MRCK Beta, Human 5
MYLK_HUMAN Q15746 CHEMBL2428 Myosin Light Chain Kinase, Smooth Muscle, Human 5
PAK4_HUMAN O96013 CHEMBL4482 Serine/threonine-protein Kinase PAK 4, Human 5
PGFRA_MOUSE P26618 CHEMBL3466 Platelet-derived Growth Factor Receptor Alpha, Mouse 5
PGFRB_MOUSE P05622 CHEMBL2749 Platelet-derived Growth Factor Receptor Beta, Mouse 5
PIM3_HUMAN Q86V86 CHEMBL5407 Serine/threonine-protein Kinase PIM3, Human 5
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 5
Q965D6_PLAFA Q965D6 CHEMBL4513 3-oxoacyl-acyl-carrier Protein Reductase, Plafa 5
RET_HUMAN P07949 CHEMBL2041 Tyrosine-protein Kinase Receptor RET, Human 5
ST17A_HUMAN Q9UEE5 CHEMBL4525 Serine/threonine-protein Kinase 17A, Human 5
STK36_HUMAN Q9NRP7 CHEMBL4312 Serine/threonine-protein Kinase 36, Human 5
TNI3K_HUMAN Q59H18 CHEMBL5260 Serine/threonine-protein Kinase TNNI3K, Human 5
TYK2_HUMAN P29597 CHEMBL3553 Tyrosine-protein Kinase TYK2, Human 5
UFO_HUMAN P30530 CHEMBL4895 Tyrosine-protein Kinase Receptor UFO, Human 5
VGFR3_MOUSE P35917 CHEMBL4758 Vascular Endothelial Growth Factor Receptor 3, Mouse 5
AAPK1_HUMAN Q13131 CHEMBL4045 AMP-activated Protein Kinase, Alpha-1 Subunit, Human 4
ACV1B_HUMAN P36896 CHEMBL5310 Activin Receptor Type-1B, Human 4
ALDR_RAT P07943 CHEMBL2622 Aldose Reductase, Rat 4
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 4
AVR2B_HUMAN Q13705 CHEMBL5466 Activin Receptor Type-2B, Human 4
BLK_HUMAN P51451 CHEMBL2250 Tyrosine-protein Kinase BLK, Human 4
BMP2K_HUMAN Q9NSY1 CHEMBL4522 BMP-2-inducible Protein Kinase, Human 4
CCND3_HUMAN P30281 CHEMBL2422 G1/S-specific Cyclin D3, Human 4
CCNH_HUMAN P51946 CHEMBL2165 Cyclin H, Human 4
CDK14_HUMAN O94921 CHEMBL6162 Serine/threonine-protein Kinase PFTAIRE-1, Human 4
DCLK1_HUMAN O15075 CHEMBL5683 Serine/threonine-protein Kinase DCLK1, Human 4
DDR2_HUMAN Q16832 CHEMBL5122 Discoidin Domain-containing Receptor 2, Human 4
DMPK_HUMAN Q09013 CHEMBL5320 Myotonin-protein Kinase, Human 4
EPHA6_HUMAN Q9UF33 CHEMBL4526 Ephrin Type-A Receptor 6, Human 4
EPHB4_HUMAN P54760 CHEMBL5147 Ephrin Type-B Receptor 4, Human 4
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 4
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 4
IKKE_HUMAN Q14164 CHEMBL3529 Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human 4
JAK1_HUMAN P23458 CHEMBL2835 Tyrosine-protein Kinase JAK1, Human 4
KC1AL_HUMAN Q8N752 CHEMBL5520 Casein Kinase I Isoform Alpha-like, Human 4
KKCC2_HUMAN Q96RR4 CHEMBL5284 CaM-kinase Kinase Beta, Human 4
KPCA_RAT P05696 CHEMBL2855 Protein Kinase C Alpha, Rat 4
KPCB_RAT P68403 CHEMBL3020 Protein Kinase C Beta, Rat 4
KPCD_RAT P09215 CHEMBL3633 Protein Kinase C Delta, Rat 4
KPCL_RAT Q64617 CHEMBL3990 Protein Kinase C Eta, Rat 4
KPCT_RAT Q9WTQ0 CHEMBL4563 Protein Kinase C Theta, Rat 4
KPCZ_RAT P09217 CHEMBL5379 Protein Kinase C Zeta, Rat 4
LATS2_HUMAN Q9NRM7 CHEMBL5907 Serine/threonine-protein Kinase LATS2, Human 4
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 4
M4K4_HUMAN O95819 CHEMBL6166 Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human 4
M4K5_HUMAN Q9Y4K4 CHEMBL4852 Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human 4
MARK1_HUMAN Q9P0L2 CHEMBL5940 Serine/threonine-protein Kinase MARK1, Human 4
MARK2_HUMAN Q7KZI7 CHEMBL3831 MAP/microtubule Affinity-regulating Kinase 2, Human 4
MARK3_HUMAN P27448 CHEMBL5600 Serine/threonine-protein Kinase C-TAK1, Human 4
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 4
MP2K4_HUMAN P45985 CHEMBL2897 Dual Specificity Mitogen-activated Protein Kinase Kinase 4, Human 4
MRCKA_HUMAN Q5VT25 CHEMBL4516 Serine/threonine-protein Kinase MRCK-A, Human 4
MRCKG_HUMAN Q6DT37 CHEMBL5615 Serine/threonine-protein Kinase MRCK Gamma, Human 4
NLK_HUMAN Q9UBE8 CHEMBL5364 Serine/threonine Protein Kinase NLK, Human 4
NOX4_HUMAN Q9NPH5 CHEMBL1250375 NADPH Oxidase 4, Human 4
NUAK1_HUMAN O60285 CHEMBL5784 NUAK Family SNF1-like Kinase 1, Human 4
PHKG2_HUMAN P15735 CHEMBL2349 Phosphorylase Kinase Gamma Subunit 2, Human 4
PI42B_HUMAN P78356 CHEMBL5667 Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta, Human 4
PI51A_HUMAN Q99755 CHEMBL5969 Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha, Human 4
PIM2_HUMAN Q9P1W9 CHEMBL4523 Serine/threonine-protein Kinase PIM2, Human 4
PKN1_HUMAN Q16512 CHEMBL3384 Protein Kinase N1, Human 4
PKN2_HUMAN Q16513 CHEMBL3032 Protein Kinase N2, Human 4
PTK6_HUMAN Q13882 CHEMBL4601 Tyrosine-protein Kinase BRK, Human 4
Q95J97_RABIT Q95J97 CHEMBL4885 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rabit 4
RIOK1_HUMAN Q9BRS2 CHEMBL5975 Serine/threonine-protein Kinase RIO1, Human 4
RIPK2_HUMAN O43353 CHEMBL5014 Serine/threonine-protein Kinase RIPK2, Human 4
SGK1_HUMAN O00141 CHEMBL2343 Serine/threonine-protein Kinase Sgk1, Human 4
ST32B_HUMAN Q9NY57 CHEMBL5912 Serine/threonine-protein Kinase 32B, Human 4
STK10_HUMAN O94804 CHEMBL3981 Serine/threonine-protein Kinase 10, Human 4
STK16_HUMAN O75716 CHEMBL3938 Serine/threonine-protein Kinase 16, Human 4
STK4_HUMAN Q13043 CHEMBL4598 Serine/threonine-protein Kinase MST1, Human 4
Z104299 Z104299 CHEMBL1907605 Cyclin-dependent Kinase 2/cyclin E1 4
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 3
AAPK2_HUMAN P54646 CHEMBL2116 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 3
ACVR1_HUMAN Q04771 CHEMBL5903 Activin Receptor Type-1, Human 3
ADCK4_HUMAN Q96D53 CHEMBL5753 Uncharacterized AarF Domain-containing Protein Kinase 4, Human 3
ALDR_BOVIN P16116 CHEMBL3081 Aldose Reductase, Bovin 3
ANKK1_HUMAN Q8NFD2 CHEMBL5547 Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human 3
CD5R1_HUMAN Q15078 CHEMBL2783 Cyclin-dependent Kinase 5 Regulatory Subunit 1, Human 3
CDK19_HUMAN Q9BWU1 CHEMBL6002 Cell Division Cycle 2-like Protein Kinase 6, Human 3
CDK8_HUMAN P49336 CHEMBL5719 Cell Division Protein Kinase 8, Human 3
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 3
DCLK2_HUMAN Q8N568 CHEMBL5519 Serine/threonine-protein Kinase DCLK2, Human 3
DYR1A_RAT Q63470 CHEMBL5508 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A, Rat 3
E2AK4_HUMAN Q9P2K8 CHEMBL5358 Eukaryotic Translation Initiation Factor 2-alpha Kinase 4, Human 3
EPHB2_HUMAN P29323 CHEMBL3290 Ephrin Type-B Receptor 2, Human 3
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 3
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 3
FGR_HUMAN P09769 CHEMBL4454 Tyrosine-protein Kinase FGR, Human 3
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 3
HCK_HUMAN P08631 CHEMBL3234 Tyrosine-protein Kinase HCK, Human 3
IRAK3_HUMAN Q9Y616 CHEMBL5081 Interleukin-1 Receptor-associated Kinase 3, Human 3
KAPCA_BOVIN P00517 CHEMBL2654 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Bovin 3
KAPCB_BOVIN P05131 CHEMBL3279 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Bovin 3
KCC4_HUMAN Q16566 CHEMBL2494 CaM Kinase IV, Human 3
LATS1_HUMAN O95835 CHEMBL6167 Serine/threonine-protein Kinase LATS1, Human 3
LIMK1_HUMAN P53667 CHEMBL3836 LIM Domain Kinase 1, Human 3
MAPK5_HUMAN Q8IW41 CHEMBL3094 MAP Kinase-activated Protein Kinase 5, Human 3
MARK4_HUMAN Q96L34 CHEMBL5754 MAP/microtubule Affinity-regulating Kinase 4, Human 3
MELK_HUMAN Q14680 CHEMBL4578 Maternal Embryonic Leucine Zipper Kinase, Human 3
MKNK1_HUMAN Q9BUB5 CHEMBL4718 MAP Kinase-interacting Serine/threonine-protein Kinase MNK1, Human 3
MKNK2_HUMAN Q9HBH9 CHEMBL4204 MAP Kinase Signal-integrating Kinase 2, Human 3
MP2K6_HUMAN P52564 CHEMBL2171 Dual Specificity Mitogen-activated Protein Kinase Kinase 6, Human 3
MRP1_HUMAN P33527 CHEMBL3004 Multidrug Resistance-associated Protein 1, Human 3
MST4_HUMAN Q9P289 CHEMBL5941 Serine/threonine-protein Kinase MST4, Human 3
MYLK2_HUMAN Q9H1R3 CHEMBL2777 Myosin Light Chain Kinase 2, Human 3
MYLK_CHICK P11799 CHEMBL3062 Myosin Light Chain Kinase, Smooth Muscle, Chick 3
NANH_CLOPE P10481 CHEMBL5189 Sialidase, Clope 3
NTRK2_HUMAN Q16620 CHEMBL4898 Neurotrophic Tyrosine Kinase Receptor Type 2, Human 3
PAK1_HUMAN Q13153 CHEMBL4600 Serine/threonine-protein Kinase PAK 1, Human 3
PAK3_HUMAN O75914 CHEMBL2999 Serine/threonine-protein Kinase PAK 3, Human 3
PAK6_HUMAN Q9NQU5 CHEMBL4311 Serine/threonine-protein Kinase PAK6, Human 3
PAK7_HUMAN Q9P286 CHEMBL4524 Serine/threonine-protein Kinase PAK7, Human 3
PLK3_HUMAN Q9H4B4 CHEMBL4897 Serine/threonine-protein Kinase PLK3, Human 3
Q965D5_PLAFA Q965D5 CHEMBL4150 Enoyl-acyl-carrier Protein Reductase, Plafa 3
Q965D7_PLAFA Q965D7 CHEMBL4512 Fatty Acid Synthase, Plafa 3
RIOK3_HUMAN O14730 CHEMBL5659 Serine/threonine-protein Kinase RIO3, Human 3
SIK2_HUMAN Q9H0K1 CHEMBL5699 Serine/threonine-protein Kinase SIK2, Human 3
SIRT2_HUMAN Q8IXJ6 CHEMBL4462 NAD-dependent Deacetylase Sirtuin 2, Human 3
SRPK1_HUMAN Q96SB4 CHEMBL4375 Serine/threonine-protein Kinase SRPK1, Human 3
ST17B_HUMAN O94768 CHEMBL3980 Serine/threonine-protein Kinase 17B, Human 3
STK24_HUMAN Q9Y6E0 CHEMBL5082 Serine/threonine-protein Kinase 24, Human 3
STK25_HUMAN O00506 CHEMBL5552 Serine/threonine-protein Kinase 25, Human 3
STK33_HUMAN Q9BYT3 CHEMBL6005 Serine/threonine-protein Kinase 33, Human 3
TAU_RAT P19332 CHEMBL1075117 Microtubule-associated Protein Tau, Rat 3
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 3
TIE1_HUMAN P35590 CHEMBL5274 Tyrosine-protein Kinase Receptor Tie-1, Human 3
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 3
TLK2_HUMAN Q86UE8 CHEMBL5404 Serine/threonine-protein Kinase Tousled-like 2, Human 3
TXK_HUMAN P42681 CHEMBL4367 Tyrosine-protein Kinase TXK, Human 3
YES_HUMAN P07947 CHEMBL2073 Tyrosine-protein Kinase YES, Human 3
Z104296 Z104296 CHEMBL1907602 Cyclin-dependent Kinase 1/cyclin B1 3
Z104300 Z104300 CHEMBL1907606 Mitogen-activated Protein Kinase; ERK1/ERK2 3
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 2
ABL2_HUMAN P42684 CHEMBL4014 Tyrosine-protein Kinase ABL2, Human 2
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 2
AMPC_ECOLI P00811 CHEMBL2026 Beta-lactamase, Ecoli 2
AMPH_ECOLI P0AD70 CHEMBL4413 Penicillin-binding Protein AmpH, Ecoli 2
BMPR2_HUMAN Q13873 CHEMBL5467 Bone Morphogenetic Protein Receptor Type-2, Human 2
BMX_HUMAN P51813 CHEMBL3834 Tyrosine-protein Kinase BMX, Human 2
BRSK1_HUMAN Q8TDC3 CHEMBL5650 BR Serine/threonine-protein Kinase 1, Human 2
BRSK2_HUMAN Q8IWQ3 CHEMBL4574 BR Serine/threonine-protein Kinase 2, Human 2
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 2
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 2
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 2
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 2
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 2
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 2
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 2
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 2
CCND1_HUMAN P24385 CHEMBL3610 G1/S-specific Cyclin D1, Human 2
CCND2_HUMAN P30279 CHEMBL3613 G1/S-specific Cyclin D2, Human 2
CD11A_HUMAN Q9UQ88 CHEMBL5416 PITSLRE Serine/threonine-protein Kinase CDC2L2, Human 2
CD11B_HUMAN P21127 CHEMBL5808 PITSLRE Serine/threonine-protein Kinase CDC2L1, Human 2
CDK1_YEAST P00546 CHEMBL5213 Cell Division Control Protein 28, Yeast 2
CSK21_MOUSE Q60737 CHEMBL3537 Casein Kinase II Alpha, Mouse 2
CSK21_RAT P19139 CHEMBL2661 Casein Kinase II Alpha, Rat 2
CSK2B_RAT P67874 CHEMBL2463 Casein Kinase II Beta, Rat 2
DAPK1_HUMAN P53355 CHEMBL2558 Death-associated Protein Kinase 1, Human 2
DAPK2_HUMAN Q9UIK4 CHEMBL3123 Death-associated Protein Kinase 2, Human 2
DHB1_HUMAN P14061 CHEMBL3181 Estradiol 17-beta-dehydrogenase 1, Human 2
DHB2_HUMAN P37059 CHEMBL2789 Estradiol 17-beta-dehydrogenase 2, Human 2
DKK1_HUMAN O94907 CHEMBL6024 Dickkopf-related Protein 1, Human 2
DYR1A_HUMAN Q13627 CHEMBL2292 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Human 2
DYRK2_HUMAN Q92630 CHEMBL4376 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 2, Human 2
EPHA2_HUMAN P29317 CHEMBL2068 Ephrin Type-A Receptor 2, Human 2
EPHA3_HUMAN P29320 CHEMBL4954 Ephrin Type-A Receptor 3, Human 2
EPHA4_HUMAN P54764 CHEMBL3988 Ephrin Type-A Receptor 4, Human 2
EPHA5_HUMAN P54756 CHEMBL3987 Ephrin Type-A Receptor 5, Human 2
EPHA7_HUMAN Q15375 CHEMBL4602 Ephrin Type-A Receptor 7, Human 2
EPHB1_HUMAN P54762 CHEMBL5072 Ephrin Type-B Receptor 1, Human 2
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 2
GBRA2_HUMAN P47869 CHEMBL4956 GABA Receptor Alpha-2 Subunit, Human 2
GBRA3_HUMAN P34903 CHEMBL3026 GABA Receptor Alpha-3 Subunit, Human 2
GBRA4_HUMAN P48169 CHEMBL2472 GABA Receptor Alpha-4 Subunit, Human 2
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 2
GBRA6_HUMAN Q16445 CHEMBL2579 GABA Receptor Alpha-6 Subunit, Human 2
KAP2_BOVIN P00515 CHEMBL3654 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Bovin 2
KAPCA_MOUSE P05132 CHEMBL4991 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Mouse 2
KAPCB_MOUSE P68181 CHEMBL2481 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Mouse 2
KCC1A_HUMAN Q14012 CHEMBL2493 CaM Kinase I Alpha, Human 2
KCC1D_HUMAN Q8IU85 CHEMBL5073 CaM Kinase I Delta, Human 2
LGUL_HUMAN Q04760 CHEMBL2424 Glyoxalase I, Human 2
LIMK2_HUMAN P53671 CHEMBL5932 LIM Domain Kinase 2, Human 2
LOX12_HUMAN P18054 CHEMBL3687 Arachidonate 12-lipoxygenase, Human 2
LOX15_HUMAN P16050 CHEMBL2903 Arachidonate 15-lipoxygenase, Human 2
LOX15_RABIT P12530 CHEMBL4358 Arachidonate 15-lipoxygenase, Rabit 2
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 2
LTK_HUMAN P29376 CHEMBL5627 Leukocyte Tyrosine Kinase Receptor, Human 2
M3K10_HUMAN Q02779 CHEMBL2873 Mitogen-activated Protein Kinase Kinase Kinase 10, Human 2
M3K14_HUMAN Q99558 CHEMBL5888 Mitogen-activated Protein Kinase Kinase Kinase 14, Human 2
M3K4_HUMAN Q9Y6R4 CHEMBL4853 Mitogen-activated Protein Kinase Kinase Kinase 4, Human 2
M3K5_HUMAN Q99683 CHEMBL5285 Mitogen-activated Protein Kinase Kinase Kinase 5, Human 2
MGLL_HUMAN Q99685 CHEMBL4191 Monoglyceride Lipase, Human 2
MK04_HUMAN P31152 CHEMBL5759 Mitogen-activated Protein Kinase 4, Human 2
MK06_HUMAN Q16659 CHEMBL5121 Mitogen-activated Protein Kinase 6, Human 2
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 2
MLTK_HUMAN Q9NYL2 CHEMBL3886 Mixed Lineage Kinase 7, Human 2
MP2K3_HUMAN P46734 CHEMBL2109 Dual Specificity Mitogen-activated Protein Kinase Kinase 3, Human 2
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 2
MUSK_HUMAN O15146 CHEMBL5684 Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human 2
MYLK4_HUMAN Q86YV6 CHEMBL5426 Myosin Light Chain Kinase Family Member 4, Human 2
NEK2_HUMAN P51955 CHEMBL3835 Serine/threonine-protein Kinase NEK2, Human 2
NEK5_HUMAN Q6P3R8 CHEMBL5044 Serine/threonine-protein Kinase Nek5, Human 2
NEK7_HUMAN Q8TDX7 CHEMBL4849 Serine/threonine-protein Kinase NEK7, Human 2
NEK9_HUMAN Q8TD19 CHEMBL5257 Serine/threonine-protein Kinase NEK9, Human 2
NTRK1_HUMAN P04629 CHEMBL2815 Nerve Growth Factor Receptor Trk-A, Human 2
NTRK3_HUMAN Q16288 CHEMBL5608 NT-3 Growth Factor Receptor, Human 2
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 2
P90584_PLAFA P90584 CHEMBL4090 Protein Kinase Pfmrk, Plafa 2
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 2
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 2
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 2
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 2
PRKDC_HUMAN P78527 CHEMBL3142 DNA-dependent Protein Kinase, Human 2
PRKX_HUMAN P51817 CHEMBL5818 Serine/threonine-protein Kinase PRKX, Human 2
Q5SC61_TOXGO Q5SC61 CHEMBL6051 Mitogen-activated Protein Kinase 1, Toxgo 2
Q7ZJM1_9HIV1 Q7ZJM1 CHEMBL3471 Human Immunodeficiency Virus Type 1 Integrase, 9hiv1 2
RIPK1_HUMAN Q13546 CHEMBL5464 Receptor-interacting Serine/threonine-protein Kinase 1, Human 2
ROS1_HUMAN P08922 CHEMBL5568 Proto-oncogene Tyrosine-protein Kinase ROS, Human 2
SIK1_HUMAN P57059 CHEMBL6082 Serine/threonine-protein Kinase SIK1, Human 2
SIRT1_HUMAN Q96EB6 CHEMBL4506 NAD-dependent Deacetylase Sirtuin 1, Human 2
SRMS_HUMAN Q9H3Y6 CHEMBL5703 Tyrosine-protein Kinase Srms, Human 2
SRPK2_HUMAN P78362 CHEMBL5668 Serine/threonine-protein Kinase SRPK2, Human 2
STK11_HUMAN Q15831 CHEMBL5606 Serine/threonine-protein Kinase 11, Human 2
STK3_MOUSE Q9JI10 CHEMBL4310 Serine/threonine-protein Kinase MST2, Mouse 2
TBA1A_RAT P68370 CHEMBL4139 Tubulin Alpha-1 Chain, Rat 2
TEC_HUMAN P42680 CHEMBL4246 Tyrosine-protein Kinase TEC, Human 2
TESK1_HUMAN Q15569 CHEMBL5604 Dual Specificity Testis-specific Protein Kinase 1, Human 2
TLK1_HUMAN Q9UKI8 CHEMBL5388 Serine/threonine-protein Kinase Tousled-like 1, Human 2
TYRO3_HUMAN Q06418 CHEMBL5314 Tyrosine-protein Kinase Receptor TYRO3, Human 2
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 2
XDH_BOVIN P80457 CHEMBL3649 Xanthine Dehydrogenase, Bovin 2
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 2
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
5NTD_RAT P21588 CHEMBL1075214 5'-nucleotidase, Rat 1
AAPK2_RAT Q09137 CHEMBL4637 AMP-activated Protein Kinase, Alpha-2 Subunit, Rat 1
ACK1_HUMAN Q07912 CHEMBL4599 Tyrosine Kinase Non-receptor Protein 2, Human 1
ACVL1_HUMAN P37023 CHEMBL5311 Serine/threonine-protein Kinase Receptor R3, Human 1
ADCK3_HUMAN Q8NI60 CHEMBL5550 Chaperone Activity Of Bc1 Complex-like, Mitochondrial, Human 1
AHR_HUMAN P35869 CHEMBL3201 Aryl Hydrocarbon Receptor, Human 1
AK1A1_RAT P51635 CHEMBL3871 Aldehyde Reductase, Rat 1
AK1CL_MOUSE Q91WR5 CHEMBL1075270 Aldo-keto Reductase Family 1 Member C21, Mouse 1
AOFA_BOVIN P21398 CHEMBL3254 Monoamine Oxidase A, Bovin 1
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 1
AVR2A_HUMAN P27037 CHEMBL5616 Activin Receptor Type-2A, Human 1
BGLR_RAT P06760 CHEMBL4814 Beta-glucuronidase, Rat 1
BLK_MOUSE P16277 CHEMBL3343 Tyrosine-protein Kinase BLK, Mouse 1
BMR1A_HUMAN P36894 CHEMBL5275 Bone Morphogenetic Protein Receptor Type-1A, Human 1
BTK_HUMAN Q06187 CHEMBL5251 Tyrosine-protein Kinase BTK, Human 1
CAH12_HUMAN O43570 CHEMBL3242 Carbonic Anhydrase XII, Human 1
CAH13_MOUSE Q9D6N1 CHEMBL2186 Carbonic Anhydrase XIII, Mouse 1
CAH3_HUMAN P07451 CHEMBL2885 Carbonic Anhydrase III, Human 1
CBR1_HUMAN P16152 CHEMBL5586 Carbonyl Reductase [NADPH] 1, Human 1
CCNT2_HUMAN O60583 CHEMBL1293321 Cyclin-T2, Human 1
CD38_HUMAN P28907 CHEMBL4660 Lymphocyte Differentiation Antigen CD38, Human 1
CFTR_HUMAN P13569 CHEMBL4051 Cystic Fibrosis Transmembrane Conductance Regulator, Human 1
CLK1_MOUSE P22518 CHEMBL1075280 Dual Specificity Protein Kinase CLK1, Mouse 1
CLK3_MOUSE O35492 CHEMBL1075282 Dual Specificity Protein Kinase CLK3, Mouse 1
CSK_HUMAN P41240 CHEMBL2634 Tyrosine-protein Kinase CSK, Human 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
EPHA1_HUMAN P21709 CHEMBL5810 Ephrin Type-A Receptor 1, Human 1
EPHA8_HUMAN P29322 CHEMBL4134 Ephrin Type-A Receptor 8, Human 1
ERBB4_HUMAN Q15303 CHEMBL3009 Receptor Protein-tyrosine Kinase ErbB-4, Human 1
ERG1_RAT P52020 CHEMBL4241 Squalene Monooxygenase, Rat 1
ESR1_HUMAN P03372 CHEMBL206 Estrogen Receptor Alpha, Human 1
ESR2_HUMAN Q92731 CHEMBL242 Estrogen Receptor Beta, Human 1
FABI_ECOLI P0AEK4 CHEMBL1857 Enoyl-[acyl-carrier-protein] Reductase, Ecoli 1
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 1
FER_HUMAN P16591 CHEMBL3982 Tyrosine-protein Kinase FER, Human 1
FES_HUMAN P07332 CHEMBL5455 Tyrosine-protein Kinase FES, Human 1
FGR_RAT Q6P6U0 CHEMBL4362 Tyrosine-protein Kinase FGR, Rat 1
GSK3B_MOUSE Q9WV60 CHEMBL1075321 Glycogen Synthase Kinase-3 Beta, Mouse 1
HIPK1_HUMAN Q86Z02 CHEMBL5427 Homeodomain-interacting Protein Kinase 1, Human 1
INSRR_HUMAN P14616 CHEMBL5483 Insulin Receptor-related Protein, Human 1
INSR_MOUSE P15208 CHEMBL3187 Insulin Receptor, Mouse 1
JAK3_MOUSE Q62137 CHEMBL5250 Tyrosine-protein Kinase JAK3, Mouse 1
KAPCA_RAT P27791 CHEMBL3390 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rat 1
KC1A_MOUSE Q8BK63 CHEMBL5148 Casein Kinase I Alpha, Mouse 1
KC1D_MOUSE Q9DC28 CHEMBL5175 Casein Kinase I Delta, Mouse 1
KC1E_MOUSE Q9JMK2 CHEMBL5140 Casein Kinase I Epsilon, Mouse 1
KC1G1_MOUSE Q8BTH8 CHEMBL4455 Casein Kinase I Gamma 1, Mouse 1
KC1G3_HUMAN Q9Y6M4 CHEMBL5084 Casein Kinase I Isoform Gamma-3, Human 1
KCC1G_HUMAN Q96NX5 CHEMBL5258 CaM Kinase I Gamma, Human 1
KCC2A_RAT P11275 CHEMBL2359 CaM Kinase II Alpha, Rat 1
KGP1_BOVIN P00516 CHEMBL3183 CGMP-dependent Protein Kinase 1 Alpha, Bovin 1
KPB1_HUMAN P46020 CHEMBL2905 Phosphorylase Kinase Alpha M Subunit, Human 1
KPB2_HUMAN P46019 CHEMBL2906 Phosphorylase Kinase Alpha L Subunit, Human 1
KPBB_HUMAN Q93100 CHEMBL3844 Phosphorylase Kinase Beta Subunit, Human 1
KS6B2_HUMAN Q9UBS0 CHEMBL3111 Ribosomal Protein S6 Kinase 2, Human 1
KSYK_RAT Q64725 CHEMBL4364 Tyrosine-protein Kinase SYK, Rat 1
LEF_BACAN P15917 CHEMBL4372 Anthrax Lethal Factor, Bacan 1
LOX1_SOYBN P08170 CHEMBL4586 Seed Lipoxygenase-1, Soybn 1
LOX5_RAT P12527 CHEMBL312 Arachidonate 5-lipoxygenase, Rat 1
LYN_RAT Q07014 CHEMBL4363 Tyrosine-protein Kinase Lyn, Rat 1
M3K1_HUMAN Q13233 CHEMBL3956 Mitogen-activated Protein Kinase Kinase Kinase 1, Human 1
M3K7_HUMAN O43318 CHEMBL5776 Mitogen-activated Protein Kinase Kinase Kinase 7, Human 1
MAPK3_HUMAN Q16644 CHEMBL4670 MAP Kinase-activated Protein Kinase 3, Human 1
MAT1_HUMAN P51948 CHEMBL5053 CDK-activating Kinase Assembly Factor MAT1, Human 1
MDHM_HUMAN P40926 CHEMBL5917 Malate Dehydrogenase, Mitochondrial, Human 1
MDH_THETH P10584 CHEMBL4255 Malate Dehydrogenase, Theth 1
MDR3_MOUSE P21447 CHEMBL2573 P-glycoprotein 3, Mouse 1
MINK1_HUMAN Q8N4C8 CHEMBL5518 Misshapen-like Kinase 1, Human 1
MK03_HUMAN P27361 CHEMBL3385 MAP Kinase ERK1, Human 1
MK10_RAT P49187 CHEMBL4092 C-Jun N-terminal Kinase 3, Rat 1
MP2K7_HUMAN O14733 CHEMBL3530 Dual Specificity Mitogen-activated Protein Kinase Kinase 7, Human 1
MYO3A_HUMAN Q8NEV4 CHEMBL5546 Myosin IIIA, Human 1
MYO3B_HUMAN Q8WXR4 CHEMBL5654 Myosin-IIIB, Human 1
NEK1_HUMAN Q96PY6 CHEMBL5855 Serine/threonine-protein Kinase Nek1, Human 1
NEK6_HUMAN Q9HC98 CHEMBL4309 Serine/threonine-protein Kinase NEK6, Human 1
P3C2B_HUMAN O00750 CHEMBL5554 Phosphatidylinositol-4-phosphate 3-kinase C2 Domain-containing Beta Polypeptide, Human 1
P85B_HUMAN O00459 CHEMBL4437 PI3-kinase P85-beta Subunit, Human 1
PA21B_HUMAN P04054 CHEMBL4426 Phospholipase A2 Group 1B, Human 1
PAK2_HUMAN Q13177 CHEMBL4487 Serine/threonine-protein Kinase PAK 2, Human 1
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 1
PHO85_YEAST P17157 CHEMBL5589 Cyclin-dependent Protein Kinase PHO85, Yeast 1
PK3CA_BOVIN P32871 CHEMBL2498 PI3-kinase P110-alpha Subunit, Bovin 1
PK3CA_MOUSE P42337 CHEMBL2499 PI3-kinase P110-alpha Subunit, Mouse 1
PLK2_HUMAN Q9NYY3 CHEMBL5938 Serine/threonine-protein Kinase PLK2, Human 1
PYGM_HUMAN P11217 CHEMBL3526 Muscle Glycogen Phosphorylase, Human 1
Q862F3_BOVIN Q862F3 CHEMBL4262 Tubulin Alpha Chain, Bovin 1
Q862L2_BOVIN Q862L2 CHEMBL3752 Tubulin Alpha-1 Chain, Bovin 1
Q8MMZ8_EIMTE Q8MMZ8 CHEMBL5036 CGMP-dependent Protein Kinase, Eimte 1
R1AB_CVHSA P0C6X7 CHEMBL5118 Replicase Polyprotein 1ab, Cvhsa 1
RON_HUMAN Q04912 CHEMBL2689 Macrophage-stimulating Protein Receptor, Human 1
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 1
SIRT3_HUMAN Q9NTG7 CHEMBL4461 NAD-dependent Deacetylase Sirtuin 3, Human 1
ST32C_HUMAN Q86UX6 CHEMBL5405 Serine/threonine-protein Kinase 32C, Human 1
ST38L_HUMAN Q9Y2H1 CHEMBL4851 Serine/threonine-protein Kinase 38-like, Human 1
SYK_HUMAN Q15046 CHEMBL5575 Lysyl-tRNA Synthetase, Human 1
TAB1_HUMAN Q15750 CHEMBL5605 Mitogen-activated Protein Kinase Kinase Kinase 7-interacting Protein 1, Human 1
TAOK1_HUMAN Q7L7X3 CHEMBL5261 Serine/threonine-protein Kinase TAO1, Human 1
TAOK3_HUMAN Q9H2K8 CHEMBL5701 Serine/threonine-protein Kinase TAO3, Human 1
TBB2B_BOVIN Q6B856 CHEMBL3394 Tubulin Beta Chain, Bovin 1
TNK1_HUMAN Q13470 CHEMBL5334 Non-receptor Tyrosine-protein Kinase TNK1, Human 1
TOP1_RAT Q9WUL0 CHEMBL1075164 DNA Topoisomerase 1, Rat 1
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 1
TSSK1_HUMAN Q9BXA7 CHEMBL6003 Testis-specific Serine/threonine-protein Kinase 1, Human 1
ULK3_MOUSE Q3U3Q1 CHEMBL3832 ULK3 Kinase, Mouse 1
ZAP70_HUMAN P43403 CHEMBL2803 Tyrosine-protein Kinase ZAP-70, Human 1

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