UCSF

HM74 Nicotinic Acid GPCR, Mouse (70 Compounds)

Swissprot:
HCAR2_MOUSE
Stitch:
HCAR2_MOUSE
UniProt:
Q9EP66
ChEMBL:
CHEMBL4420
Reactome:
REACT_261161
REACT_250376
REACT_198712

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 70 1 1 1
Binding ≤ 1μM 42 1 1 1
Functional ≤ 10μM 5 2 1 1

Reactome Network (3)

Reactome ID Description Species
REACT_261161 Class A/1 (Rhodopsin-like receptors) Mus musculus
REACT_250376 G alpha (i) signalling events Mus musculus
REACT_198712 Hydroxycarboxylic acid-binding receptors Mus musculus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
HCAR2_HUMAN Q8TDS4 CHEMBL3785 Nicotinic Acid Receptor 1, Human 365 20 5 3
HCAR2_RAT Q80Z39 CHEMBL4731 HM74 Nicotinic Acid GPCR, Rat 19 8 3 1

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
HCAR2-1-E HM74 Nicotinic Acid GPCR (cluster #1 Of 4), Eukaryotic 281 4 2 2
HCAR2-2-E HM74 Nicotinic Acid GPCR (cluster #2 Of 4), Eukaryotic 50 11 3 1
HCAR2-3-E HM74 Nicotinic Acid GPCR (cluster #3 Of 4), Eukaryotic 31 1 1 0
HCAR2-4-E HM74 Nicotinic Acid GPCR (cluster #4 Of 4), Eukaryotic 16 9 1 0
Uniprot Swissprot Chembl Description Number Shared
HCAR2_HUMAN Q8TDS4 CHEMBL3785 Nicotinic Acid Receptor 1, Human 73
HCAR2_RAT Q80Z39 CHEMBL4731 HM74 Nicotinic Acid GPCR, Rat 5
HCAR3_HUMAN P49019 CHEMBL4421 HM74 Nicotinic Acid GPCR, Human 2
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 2
Z50588 Z50588 CHEMBL373 Canis Familiaris 1

Most Common Rings