UCSF

Heat Shock Protein Beta-1, Human (6 Compounds)

Swissprot:
HSPB1_HUMAN
Stitch:
HSPB1_HUMAN
UniProt:
P04792
ChEMBL:
CHEMBL5976
Reactome:
REACT_25325
REACT_228166
PDB:
3Q9P (DOCK)
3Q9Q (DOCK)
HSPB1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 6 2 1 2
Binding ≤ 1μM 6 2 1 2

Reactome Network (2)

Reactome ID Description Species
REACT_25325 AUF1 (hnRNP D0) destabilizes mRNA Homo sapiens
REACT_228166 VEGFA-VEGFR2 Pathway Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 1
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 3
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 1
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 6
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 6
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 3
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 2
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 2
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 1
ANKK1_HUMAN Q8NFD2 CHEMBL5547 Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human 1
BLK_HUMAN P51451 CHEMBL2250 Tyrosine-protein Kinase BLK, Human 1
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 1
CDK19_HUMAN Q9BWU1 CHEMBL6002 Cell Division Cycle 2-like Protein Kinase 6, Human 1
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 1
CDK8_HUMAN P49336 CHEMBL5719 Cell Division Protein Kinase 8, Human 1
CSF1R_HUMAN P07333 CHEMBL1844 Macrophage Colony Stimulating Factor Receptor, Human 1
CTRO_HUMAN O14578 CHEMBL5579 Citron Rho-interacting Kinase, Human 1
DDR1_HUMAN Q08345 CHEMBL5319 Epithelial Discoidin Domain-containing Receptor 1, Human 1
DDR2_HUMAN Q16832 CHEMBL5122 Discoidin Domain-containing Receptor 2, Human 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
EPHA1_HUMAN P21709 CHEMBL5810 Ephrin Type-A Receptor 1, Human 1
EPHA2_HUMAN P29317 CHEMBL2068 Ephrin Type-A Receptor 2, Human 1
EPHA3_HUMAN P29320 CHEMBL4954 Ephrin Type-A Receptor 3, Human 1
EPHA4_HUMAN P54764 CHEMBL3988 Ephrin Type-A Receptor 4, Human 1
EPHA5_HUMAN P54756 CHEMBL3987 Ephrin Type-A Receptor 5, Human 1
EPHA6_HUMAN Q9UF33 CHEMBL4526 Ephrin Type-A Receptor 6, Human 1
EPHA7_HUMAN Q15375 CHEMBL4602 Ephrin Type-A Receptor 7, Human 1
EPHA8_HUMAN P29322 CHEMBL4134 Ephrin Type-A Receptor 8, Human 1
EPHB1_HUMAN P54762 CHEMBL5072 Ephrin Type-B Receptor 1, Human 1
EPHB2_HUMAN P29323 CHEMBL3290 Ephrin Type-B Receptor 2, Human 1
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 1
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 1
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 1
FRK_HUMAN P42685 CHEMBL4223 Tyrosine-protein Kinase FRK, Human 1
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 1
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 1
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 1
LCK_MOUSE P06240 CHEMBL2480 Tyrosine-protein Kinase LCK, Mouse 1
LTK_HUMAN P29376 CHEMBL5627 Leukocyte Tyrosine Kinase Receptor, Human 1
M4K4_HUMAN O95819 CHEMBL6166 Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human 1
MERTK_HUMAN Q12866 CHEMBL5331 Proto-oncogene Tyrosine-protein Kinase MER, Human 1
MK09_HUMAN P45984 CHEMBL4179 C-Jun N-terminal Kinase 2, Human 1
MK10_HUMAN P53779 CHEMBL2637 C-Jun N-terminal Kinase 3, Human 1
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 1
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 1
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 1
MK15_HUMAN Q8TD08 CHEMBL5198 Mitogen-activated Protein Kinase 15, Human 1
MKNK2_HUMAN Q9HBH9 CHEMBL4204 MAP Kinase Signal-integrating Kinase 2, Human 1
MLTK_HUMAN Q9NYL2 CHEMBL3886 Mixed Lineage Kinase 7, Human 1
MRCKA_HUMAN Q5VT25 CHEMBL4516 Serine/threonine-protein Kinase MRCK-A, Human 1
MRCKB_HUMAN Q9Y5S2 CHEMBL5052 Serine/threonine-protein Kinase MRCK Beta, Human 1
MRCKG_HUMAN Q6DT37 CHEMBL5615 Serine/threonine-protein Kinase MRCK Gamma, Human 1
MUSK_HUMAN O15146 CHEMBL5684 Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human 1
NLK_HUMAN Q9UBE8 CHEMBL5364 Serine/threonine Protein Kinase NLK, Human 1
NTRK1_HUMAN P04629 CHEMBL2815 Nerve Growth Factor Receptor Trk-A, Human 1
NTRK2_HUMAN Q16620 CHEMBL4898 Neurotrophic Tyrosine Kinase Receptor Type 2, Human 1
NTRK3_HUMAN Q16288 CHEMBL5608 NT-3 Growth Factor Receptor, Human 1
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 1
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 1
RET_HUMAN P07949 CHEMBL2041 Tyrosine-protein Kinase Receptor RET, Human 1
SLK_HUMAN Q9H2G2 CHEMBL4202 Serine/threonine-protein Kinase 2, Human 1
STK10_HUMAN O94804 CHEMBL3981 Serine/threonine-protein Kinase 10, Human 1
TIE1_HUMAN P35590 CHEMBL5274 Tyrosine-protein Kinase Receptor Tie-1, Human 1
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 1
TNFA_HUMAN P01375 CHEMBL1825 TNF-alpha, Human 1
TNIK_HUMAN Q9UKE5 CHEMBL4527 TRAF2- And NCK-interacting Kinase, Human 1
TTK_HUMAN P33981 CHEMBL3983 Dual Specificity Protein Kinase TTK, Human 1
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 1
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 1
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 1
YES_HUMAN P07947 CHEMBL2073 Tyrosine-protein Kinase YES, Human 1