UCSF

Voltage-gated Potassium Channel Subunit Kv1.5, Human (537 Compounds)

Swissprot:
KCNA5_HUMAN
Stitch:
KCNA5_HUMAN
UniProt:
P22460
ChEMBL:
CHEMBL4306
Reactome:
REACT_75770
PDB:
KCNA5

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 537 11 5 5
Binding ≤ 1μM 410 0 1 0
Functional ≤ 10μM 86 1 1 1

Reactome Network (1)

Reactome ID Description Species
REACT_75770 Voltage gated Potassium channels Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
KCNA1_HUMAN Q09470 CHEMBL2309 Voltage-gated Potassium Channel Subunit Kv1.1, Human 6
KCNA2_HUMAN P16389 CHEMBL2086 Voltage-gated Potassium Channel Subunit Kv1.2, Human 4
KCNA3_HUMAN P22001 CHEMBL4633 Voltage-gated Potassium Channel Subunit Kv1.3, Human 51
KCNA4_HUMAN P22459 CHEMBL4205 Voltage-gated Potassium Channel Subunit Kv1.4, Human 2
KCNA7_HUMAN Q96RP8 CHEMBL2773 Voltage-gated Potassium Channel Subunit Kv1.7, Human 1
KCND3_HUMAN Q9UK17 CHEMBL1964 Voltage-gated Potassium Channel Subunit Kv4.3, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 26
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
KCNA1_HUMAN Q09470 CHEMBL2309 Voltage-gated Potassium Channel Subunit Kv1.1, Human 13 2 0 0
KCNA2_HUMAN P16389 CHEMBL2086 Voltage-gated Potassium Channel Subunit Kv1.2, Human 7 0 0 0
KCNA3_HUMAN P22001 CHEMBL4633 Voltage-gated Potassium Channel Subunit Kv1.3, Human 232 11 7 1
KCNA4_HUMAN P22459 CHEMBL4205 Voltage-gated Potassium Channel Subunit Kv1.4, Human 2 1 0 0
KCNA7_HUMAN Q96RP8 CHEMBL2773 Voltage-gated Potassium Channel Subunit Kv1.7, Human 1 1 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
KCNA5-1-E Voltage-gated Potassium Channel Subunit Kv1.5 (cluster #1 Of 3), Eukaryotic 533 9 5 5
KCNA5-2-E Voltage-gated Potassium Channel Subunit Kv1.5 (cluster #2 Of 3), Eukaryotic 1 0 0 0
KCNA5-3-E Voltage-gated Potassium Channel Subunit Kv1.5 (cluster #3 Of 3), Eukaryotic 5 2 0 0
Uniprot Swissprot Chembl Description Number Shared
KCNA3_HUMAN P22001 CHEMBL4633 Voltage-gated Potassium Channel Subunit Kv1.3, Human 51
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 22
KCNA1_HUMAN Q09470 CHEMBL2309 Voltage-gated Potassium Channel Subunit Kv1.1, Human 6
KCND2_RAT Q63881 CHEMBL1075227 Potassium Voltage-gated Channel Subfamily D Member 2, Rat 6
SCN5A_HUMAN Q14524 CHEMBL1980 Sodium Channel Protein Type V Alpha Subunit, Human 5
KCNA2_HUMAN P16389 CHEMBL2086 Voltage-gated Potassium Channel Subunit Kv1.2, Human 4
KCNB1_RAT P15387 CHEMBL1075226 Potassium Voltage-gated Channel Subfamily B Member 1, Rat 4
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 4
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 4
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 4
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 4
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 4
KCNA3_MOUSE P16390 CHEMBL4818 Voltage-gated Potassium Channel Subunit Kv1.3, Mouse 3
KCNA4_HUMAN P22459 CHEMBL4205 Voltage-gated Potassium Channel Subunit Kv1.4, Human 2
Z100759 Z100759 CHEMBL614167 T-lymphocytes 2
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 1
CAC1A_RAT P54282 CHEMBL4417 Voltage-gated P/Q-type Calcium Channel Alpha-1A Subunit, Rat 1
CAC1B_RAT Q02294 CHEMBL5107 Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Rat 1
CAC1C_HUMAN Q13936 CHEMBL1940 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human 1
CAC1C_RABIT P15381 CHEMBL2830 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rabit 1
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 1
CAC1D_HUMAN Q01668 CHEMBL4138 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human 1
CAC1D_RAT P27732 CHEMBL4132 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat 1
CAC1E_RAT Q07652 CHEMBL4115 Voltage-gated R-type Calcium Channel Alpha-1E Subunit, Rat 1
CAC1G_RAT O54898 CHEMBL4257 Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Rat 1
CAC1H_RAT Q9EQ60 CHEMBL5134 Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Rat 1
CAC1I_RAT Q9Z0Y8 CHEMBL5459 Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Rat 1
KCNA7_HUMAN Q96RP8 CHEMBL2773 Voltage-gated Potassium Channel Subunit Kv1.7, Human 1
KCND3_HUMAN Q9UK17 CHEMBL1964 Voltage-gated Potassium Channel Subunit Kv4.3, Human 1
KCNN4_HUMAN O15554 CHEMBL4305 Intermediate Conductance Calcium-activated Potassium Channel Protein 4, Human 1
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 1

Most Common Rings