ZINC 12

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Swissprot:: KIF11_HUMAN
Stitch:: KIF11_HUMAN
UniProt:: P52732
ChEMBL:: CHEMBL4581
Reactome:: REACT_25201; REACT_121399
PDB:: 1II6 (DOCK); 1Q0B (DOCK); 1X88 (DOCK); 1YRS (DOCK); 2FKY (DOCK); 2FL2 (DOCK); 2FL6 (DOCK); 2FME (DOCK); 2G1Q (DOCK); 2GM1 (DOCK); 2IEH (DOCK); 2PG2 (DOCK); 2Q2Y (DOCK); 2Q2Z (DOCK); 2UYI (DOCK); 2UYM (DOCK); 2WOG (DOCK); 2X2R (DOCK); 2X7C (DOCK); 2X7D (DOCK); 2X7E (DOCK); 2XAE (DOCK); 3CJO (DOCK); 3HQD (DOCK); 3K3B (DOCK); 3K5E (DOCK); 3KEN (DOCK); 3L9H (DOCK); KIF11

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	773	39	2	12
Binding ≤ 1μM	552	21	2	10
Functional ≤ 10μM	97	7	1	4

Reactome ID	Description	Species
REACT_25201	Kinesins	Homo sapiens
REACT_121399	MHC class II antigen presentation	Homo sapiens

Code	Description	Substances	Purchasable	Natural	In Man
KIF11-1-E	Kinesin-like Protein 1 (cluster #1 Of 2), Eukaryotic	711	21	0	13
KIF11-2-E	Kinesin-like Protein 1 (cluster #2 Of 2), Eukaryotic	72	19	2	1

Uniprot	Swissprot	Chembl	Description	Number Shared
Z81034	Z81034	CHEMBL614004	A2780 (Ovarian Carcinoma Cells)	41
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	26
AURKA_HUMAN	O14965	CHEMBL4722	Serine/threonine-protein Kinase Aurora-A, Human	10
Z81247	Z81247	CHEMBL399	HeLa (Cervical Adenocarcinoma Cells)	8
Z80928	Z80928	CHEMBL394	HCT-116 (Colon Carcinoma Cells)	7
Z80186	Z80186	CHEMBL385	K562 (Erythroleukemia Cells)	4
Z80877	Z80877	CHEMBL612255	NCI-H1299 (Non-small Cell Lung Carcinoma)	4
Z100753	Z100753	CHEMBL612569	SHP77 (Small Cell Lung Carcinoma Cells)	1
Z80064	Z80064	CHEMBL382	CCRF-CEM (T-cell Leukemia)	1
Z80125	Z80125	CHEMBL613508	DU-145 (Prostate Carcinoma)	1
Z80244	Z80244	CHEMBL614335	MDA-MB-468 (Breast Adenocarcinoma)	1
Z80362	Z80362	CHEMBL389	P388 (Lymphoma Cells)	1
Z80390	Z80390	CHEMBL390	PC-3 (Prostate Carcinoma Cells)	1
Z81170	Z81170	CHEMBL612518	LNCaP (Prostate Carcinoma)	1
Z81199	Z81199	CHEMBL612440	NCI-H446 (Small Cell Lung Carcinoma Cells)	1
Z81225	Z81225	CHEMBL614073	M109 (Lung Carcinoma Cells)	1
Z81252	Z81252	CHEMBL400	MDA-MB-231 (Breast Adenocarcinoma Cells)	1
Z81331	Z81331	CHEMBL612262	SW-620 (Colon Adenocarcinoma Cells)	1