UCSF

MAP Kinase P38 Gamma, Mouse (38 Compounds)

Swissprot:
MK12_MOUSE
Stitch:
MK12_MOUSE
UniProt:
O08911
ChEMBL:
CHEMBL2445
Reactome:
REACT_205688
REACT_258600
REACT_243212
REACT_211125
REACT_207601
REACT_257088
PDB:
Mapk12

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 38 0 0 0
Binding ≤ 1μM 38 0 0 0

Reactome Network (6)

Reactome ID Description Species
REACT_205688 Activation of PPARGC1A (PGC-1alpha) by phosphorylation Mus musculus
REACT_258600 CDO in myogenesis Mus musculus
REACT_243212 DSCAM interactions Mus musculus
REACT_211125 NOD1/2 Signaling Pathway Mus musculus
REACT_207601 p38MAPK events Mus musculus
REACT_257088 VEGFA-VEGFR2 Pathway Mus musculus
Uniprot Swissprot Chembl Description Number Shared
MK11_MOUSE Q9WUI1 CHEMBL4335 MAP Kinase P38 Beta, Mouse 38
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 38

CDO in myogenesis

Uniprot Swissprot Chembl Description Number Shared
MK11_MOUSE Q9WUI1 CHEMBL4335 MAP Kinase P38 Beta, Mouse 38
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 38

DSCAM interactions

Uniprot Swissprot Chembl Description Number Shared
MK11_MOUSE Q9WUI1 CHEMBL4335 MAP Kinase P38 Beta, Mouse 38
MK13_MOUSE Q9Z1B7 CHEMBL4387 MAP Kinase P38 Delta, Mouse 38
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 38

NOD1/2 Signaling Pathway

Uniprot Swissprot Chembl Description Number Shared
MK11_MOUSE Q9WUI1 CHEMBL4335 MAP Kinase P38 Beta, Mouse 38
MK13_MOUSE Q9Z1B7 CHEMBL4387 MAP Kinase P38 Delta, Mouse 38
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 38

p38MAPK events

Uniprot Swissprot Chembl Description Number Shared
MK11_MOUSE Q9WUI1 CHEMBL4335 MAP Kinase P38 Beta, Mouse 38
MK13_MOUSE Q9Z1B7 CHEMBL4387 MAP Kinase P38 Delta, Mouse 38
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 38

VEGFA-VEGFR2 Pathway

Uniprot Swissprot Chembl Description Number Shared
MK11_MOUSE Q9WUI1 CHEMBL4335 MAP Kinase P38 Beta, Mouse 38
MK13_MOUSE Q9Z1B7 CHEMBL4387 MAP Kinase P38 Delta, Mouse 38
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 38
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 292 20 5 13
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
MK11_MOUSE Q9WUI1 CHEMBL4335 MAP Kinase P38 Beta, Mouse 52 0 0 0
MK13_MOUSE Q9Z1B7 CHEMBL4387 MAP Kinase P38 Delta, Mouse 38 0 0 0
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 220 5 1 7

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
MK12-1-E MAP Kinase P38 Gamma (cluster #1 Of 2), Eukaryotic 329 18 5 12
MK12-2-E MAP Kinase P38 Gamma (cluster #2 Of 2), Eukaryotic 2 2 0 1
Uniprot Swissprot Chembl Description Number Shared
MK11_MOUSE Q9WUI1 CHEMBL4335 MAP Kinase P38 Beta, Mouse 38
MK13_MOUSE Q9Z1B7 CHEMBL4387 MAP Kinase P38 Delta, Mouse 38
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 38
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 1
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 1
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1