Warning: session_start() [function.session-start]: open(/tmp/session/sess_pbmhj4rpdila5sjsrvg757vsg5, O_RDWR) failed: No such file or directory (2) in /domains/zinc12/htdocs/lib/auth/DrupalAuthentication.php on line 251

Warning: session_write_close() [function.session-write-close]: open(/tmp/session/sess_pbmhj4rpdila5sjsrvg757vsg5, O_RDWR) failed: No such file or directory (2) in /domains/zinc12/htdocs/lib/zinc/user/ZincAuthentication.php on line 109

Warning: session_write_close() [function.session-write-close]: Failed to write session data (files). Please verify that the current setting of session.save_path is correct (/tmp/session) in /domains/zinc12/htdocs/lib/zinc/user/ZincAuthentication.php on line 109
PA21B_HUMAN - Phospholipase A2 Group 1B, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

Phospholipase A2 Group 1B, Human (133 Compounds)

Swissprot:
PA21B_HUMAN
Stitch:
PA21B_HUMAN
UniProt:
P04054
ChEMBL:
CHEMBL4426
Reactome:
REACT_120829
REACT_121369
REACT_121324
REACT_120722
REACT_121384
REACT_120906
PDB:
1YSK (DOCK)
3ELO (DOCK)
PLA2G1B

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 133 5 7 2
Binding ≤ 1μM 94 1 1 1

Reactome Network (6)

Reactome ID Description Species
REACT_120829 Acyl chain remodelling of PC Homo sapiens
REACT_121369 Acyl chain remodelling of PE Homo sapiens
REACT_121324 Acyl chain remodelling of PG Homo sapiens
REACT_120722 Acyl chain remodelling of PI Homo sapiens
REACT_121384 Acyl chain remodelling of PS Homo sapiens
REACT_120906 Synthesis of PA Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 30
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 48
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 61
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 7
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 11
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 6
PA2GX_HUMAN O15496 CHEMBL4342 Group X Secretory Phospholipase A2, Human 19

Acyl chain remodelling of PE

Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 30
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 48
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 61
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 7
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 11
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 6
PA2GX_HUMAN O15496 CHEMBL4342 Group X Secretory Phospholipase A2, Human 19

Acyl chain remodelling of PG

Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 30
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 48
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 61
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 7
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 11
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 6
PA2GX_HUMAN O15496 CHEMBL4342 Group X Secretory Phospholipase A2, Human 19

Acyl chain remodelling of PI

Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 30
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 48
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 61
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 7
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 11
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 6
PA2GX_HUMAN O15496 CHEMBL4342 Group X Secretory Phospholipase A2, Human 19

Acyl chain remodelling of PS

Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 30
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 48
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 61
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 7
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 11
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 6
PA2GX_HUMAN O15496 CHEMBL4342 Group X Secretory Phospholipase A2, Human 19

Synthesis of PA

Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 30
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 48
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 61
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 7
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 11
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 6
PA2GX_HUMAN O15496 CHEMBL4342 Group X Secretory Phospholipase A2, Human 19
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PA21B_MOUSE Q9Z0Y2 CHEMBL4378 Phospholipase A2 Group 1B, Mouse 15 1 1 1
PA21B_NAJME P00599 CHEMBL3967 Phospholipase A2 Isozyme DE-I, Najme 2 1 1 0
PA21B_NAJMO P00602 CHEMBL3968 Phospholipase A2 Isozyme CM-I, Najmo 1 0 0 0
PA21B_PIG P00592 CHEMBL4715 Phospholipase A2 Group 1B, Pig 35 4 1 1
PA21B_RAT P04055 CHEMBL5016 Phospholipase A2 Group 1B, Rat 8 0 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
PA21B-1-E Phospholipase A2 Group 1B (cluster #1 Of 3), Eukaryotic 19 2 0 0
PA21B-2-E Phospholipase A2 Group 1B (cluster #2 Of 3), Eukaryotic 146 4 6 2
PA21B-3-E Phospholipase A2 Group 1B (cluster #3 Of 3), Eukaryotic 12 3 2 0
Uniprot Swissprot Chembl Description Number Shared
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 61
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 48
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 30
PA2GX_HUMAN O15496 CHEMBL4342 Group X Secretory Phospholipase A2, Human 19
PA21B_MOUSE Q9Z0Y2 CHEMBL4378 Phospholipase A2 Group 1B, Mouse 11
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 11
PA2GE_MOUSE Q9QUL3 CHEMBL4201 Group IIE Secretory Phospholipase A2, Mouse 11
PA2G5_MOUSE P97391 CHEMBL4167 Phospholipase A2 Group V, Mouse 9
PA2GX_MOUSE Q9QXX3 CHEMBL4200 Group X Secretory Phospholipase A2, Mouse 9
PA21B_PIG P00592 CHEMBL4715 Phospholipase A2 Group 1B, Pig 7
PA2GA_MOUSE P31482 CHEMBL5761 Phospholipase A2, Membrane Associated, Mouse 7
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 7
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 6
PAFA_HUMAN Q13093 CHEMBL3514 LDL-associated Phospholipase A2, Human 6
PA2GD_MOUSE Q9WVF6 CHEMBL5537 Group IID Secretory Phospholipase A2, Mouse 4
PA2GF_MOUSE Q9QZT4 CHEMBL5361 Group IIF Secretory Phospholipase A2, Mouse 4
Q6UB75_PIG Q6UB75 CHEMBL3651 Group VII Phospholipase A2, Pig 4
PA2_APIME P00630 CHEMBL4807 Phospholipase A2 (Bee), Apime 3
5NTD_RAT P21588 CHEMBL1075214 5'-nucleotidase, Rat 1
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1
ABCG2_HUMAN Q9UNQ0 CHEMBL5393 ATP-binding Cassette Sub-family G Member 2, Human 1
AK1A1_RAT P51635 CHEMBL3871 Aldehyde Reductase, Rat 1
AK1CL_MOUSE Q91WR5 CHEMBL1075270 Aldo-keto Reductase Family 1 Member C21, Mouse 1
ALDR_BOVIN P16116 CHEMBL3081 Aldose Reductase, Bovin 1
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 1
ALDR_RAT P07943 CHEMBL2622 Aldose Reductase, Rat 1
AMPC_ECOLI P00811 CHEMBL2026 Beta-lactamase, Ecoli 1
AMPH_ECOLI P0AD70 CHEMBL4413 Penicillin-binding Protein AmpH, Ecoli 1
AOFA_BOVIN P21398 CHEMBL3254 Monoamine Oxidase A, Bovin 1
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 1
CAH12_HUMAN O43570 CHEMBL3242 Carbonic Anhydrase XII, Human 1
CAH13_MOUSE Q9D6N1 CHEMBL2186 Carbonic Anhydrase XIII, Mouse 1
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 1
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 1
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 1
CAH3_HUMAN P07451 CHEMBL2885 Carbonic Anhydrase III, Human 1
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 1
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 1
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 1
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 1
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 1
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 1
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1, Human 1
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 1
CSK2B_HUMAN P67870 CHEMBL2358 Casein Kinase II Beta, Human 1
DHB2_HUMAN P37059 CHEMBL2789 Estradiol 17-beta-dehydrogenase 2, Human 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 1
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 1
LGUL_HUMAN Q04760 CHEMBL2424 Glyoxalase I, Human 1
LOX12_HUMAN P18054 CHEMBL3687 Arachidonate 12-lipoxygenase, Human 1
LOX15_HUMAN P16050 CHEMBL2903 Arachidonate 15-lipoxygenase, Human 1
LOX15_RABIT P12530 CHEMBL4358 Arachidonate 15-lipoxygenase, Rabit 1
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1
LOX5_RAT P12527 CHEMBL312 Arachidonate 5-lipoxygenase, Rat 1
MDH_THETH P10584 CHEMBL4255 Malate Dehydrogenase, Theth 1
MRP1_HUMAN P33527 CHEMBL3004 Multidrug Resistance-associated Protein 1, Human 1
NANH_CLOPE P10481 CHEMBL5189 Sialidase, Clope 1
NOX4_HUMAN Q9NPH5 CHEMBL1250375 NADPH Oxidase 4, Human 1
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 1
P85B_HUMAN O00459 CHEMBL4437 PI3-kinase P85-beta Subunit, Human 1
PA2_CROAD P00623 CHEMBL5711 Phospholipase A2 Alpha, Croad 1
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 1
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 1
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 1
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 1
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 1
Q965D5_PLAFA Q965D5 CHEMBL4150 Enoyl-acyl-carrier Protein Reductase, Plafa 1
Q965D6_PLAFA Q965D6 CHEMBL4513 3-oxoacyl-acyl-carrier Protein Reductase, Plafa 1
Q965D7_PLAFA Q965D7 CHEMBL4512 Fatty Acid Synthase, Plafa 1
R1AB_CVHSA P0C6X7 CHEMBL5118 Replicase Polyprotein 1ab, Cvhsa 1
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 1
XDH_BOVIN P80457 CHEMBL3649 Xanthine Dehydrogenase, Bovin 1
XDH_HUMAN P47989 CHEMBL1929 Xanthine Dehydrogenase, Human 1