UCSF

Cytosolic Phospholipase A2 Gamma, Human (22 Compounds)

Swissprot:
PA24C_HUMAN
Stitch:
PA24C_HUMAN
UniProt:
Q9UP65
ChEMBL:
CHEMBL4834
Reactome:
REACT_120829
REACT_121369
REACT_120722
REACT_120977
REACT_120785
PDB:
PLA2G4C

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 22 1 1 0
Binding ≤ 1μM 17 1 1 0
Functional ≤ 10μM 2 0 0 0

Reactome Network (5)

Reactome ID Description Species
REACT_120829 Acyl chain remodelling of PC Homo sapiens
REACT_121369 Acyl chain remodelling of PE Homo sapiens
REACT_120722 Acyl chain remodelling of PI Homo sapiens
REACT_120977 Hydrolysis of LPC Homo sapiens
REACT_120785 Hydrolysis of LPE Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 24
PA24B_HUMAN P0C869 CHEMBL4136 Phospholipase A2 Group 1VB, Human 23
PA24D_HUMAN Q86XP0 CHEMBL2287 Phospholipase A2 Group 1VD, Human 22
PA2G6_HUMAN O60733 CHEMBL3213 Calcium-independent Phospholipase A2, Human 22

Acyl chain remodelling of PE

Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 24
PA24B_HUMAN P0C869 CHEMBL4136 Phospholipase A2 Group 1VB, Human 23
PA24D_HUMAN Q86XP0 CHEMBL2287 Phospholipase A2 Group 1VD, Human 22
PA2G6_HUMAN O60733 CHEMBL3213 Calcium-independent Phospholipase A2, Human 22

Acyl chain remodelling of PI

Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 24
PA24D_HUMAN Q86XP0 CHEMBL2287 Phospholipase A2 Group 1VD, Human 22

Hydrolysis of LPC

Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 24
PA24B_HUMAN P0C869 CHEMBL4136 Phospholipase A2 Group 1VB, Human 23
PA24D_HUMAN Q86XP0 CHEMBL2287 Phospholipase A2 Group 1VD, Human 22

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PA24C-1-E Cytosolic Phospholipase A2 Gamma (cluster #1 Of 2), Eukaryotic 21 0 0 0
PA24C-2-E Cytosolic Phospholipase A2 Gamma (cluster #2 Of 2), Eukaryotic 1 1 1 0
Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 24
PA24B_HUMAN P0C869 CHEMBL4136 Phospholipase A2 Group 1VB, Human 23
PA24D_HUMAN Q86XP0 CHEMBL2287 Phospholipase A2 Group 1VD, Human 22
PA2G6_HUMAN O60733 CHEMBL3213 Calcium-independent Phospholipase A2, Human 22
FAAH1_RAT P97612 CHEMBL3229 Anandamide Amidohydrolase, Rat 2
FAAH1_HUMAN O00519 CHEMBL2243 Anandamide Amidohydrolase, Human 1
MGLL_HUMAN Q99685 CHEMBL4191 Monoglyceride Lipase, Human 1