UCSF

Group X Secretory Phospholipase A2, Human (49 Compounds)

Swissprot:
PA2GX_HUMAN
Stitch:
PA2GX_HUMAN
UniProt:
O15496
ChEMBL:
CHEMBL4342
Reactome:
REACT_120829
REACT_121369
REACT_121324
REACT_120722
REACT_121384
REACT_120906
PDB:
1LE6 (DOCK)
1LE7 (DOCK)
PLA2G10

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 49 1 1 1
Binding ≤ 1μM 32 1 1 1
Uniprot Swissprot Chembl Description Number Shared
PA21B_HUMAN P04054 CHEMBL4426 Phospholipase A2 Group 1B, Human 19
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 24
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 27
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 10
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 13
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 9

Acyl chain remodelling of PE

Uniprot Swissprot Chembl Description Number Shared
PA21B_HUMAN P04054 CHEMBL4426 Phospholipase A2 Group 1B, Human 19
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 24
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 27
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 10
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 13
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 9

Acyl chain remodelling of PG

Uniprot Swissprot Chembl Description Number Shared
PA21B_HUMAN P04054 CHEMBL4426 Phospholipase A2 Group 1B, Human 19
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 24
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 27
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 10
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 13
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 9

Acyl chain remodelling of PI

Uniprot Swissprot Chembl Description Number Shared
PA21B_HUMAN P04054 CHEMBL4426 Phospholipase A2 Group 1B, Human 19
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 24
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 27
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 10
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 13
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 9

Acyl chain remodelling of PS

Uniprot Swissprot Chembl Description Number Shared
PA21B_HUMAN P04054 CHEMBL4426 Phospholipase A2 Group 1B, Human 19
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 24
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 27
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 10
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 13
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 9

Synthesis of PA

Uniprot Swissprot Chembl Description Number Shared
PA21B_HUMAN P04054 CHEMBL4426 Phospholipase A2 Group 1B, Human 19
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 24
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 27
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 10
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 13
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 9
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PA2GX_MOUSE Q9QXX3 CHEMBL4200 Group X Secretory Phospholipase A2, Mouse 10 1 1 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PA2GX-1-E Group X Secretory Phospholipase A2 (cluster #1 Of 2), Eukaryotic 42 1 1 1
PA2GX-2-E Group X Secretory Phospholipase A2 (cluster #2 Of 2), Eukaryotic 8 0 0 0
Uniprot Swissprot Chembl Description Number Shared
PA2GA_HUMAN P14555 CHEMBL3474 Phospholipase A2 Group IIA, Human 27
PA2G5_HUMAN P39877 CHEMBL4323 Phospholipase A2 Group V, Human 24
PA21B_HUMAN P04054 CHEMBL4426 Phospholipase A2 Group 1B, Human 19
PA21B_MOUSE Q9Z0Y2 CHEMBL4378 Phospholipase A2 Group 1B, Mouse 13
PA2G5_MOUSE P97391 CHEMBL4167 Phospholipase A2 Group V, Mouse 13
PA2GE_HUMAN Q9NZK7 CHEMBL2154 Group IIE Secretory Phospholipase A2, Human 13
PA2GA_MOUSE P31482 CHEMBL5761 Phospholipase A2, Membrane Associated, Mouse 11
PA2GE_MOUSE Q9QUL3 CHEMBL4201 Group IIE Secretory Phospholipase A2, Mouse 11
PA2GD_HUMAN Q9UNK4 CHEMBL4281 Group IID Secretory Phospholipase A2, Human 10
PA2GF_HUMAN Q9BZM2 CHEMBL4278 Group IIF Secretory Phospholipase A2, Human 9
PA2GX_MOUSE Q9QXX3 CHEMBL4200 Group X Secretory Phospholipase A2, Mouse 9
PA21B_PIG P00592 CHEMBL4715 Phospholipase A2 Group 1B, Pig 7
Q6UB75_PIG Q6UB75 CHEMBL3651 Group VII Phospholipase A2, Pig 7
PA2GD_MOUSE Q9WVF6 CHEMBL5537 Group IID Secretory Phospholipase A2, Mouse 6
PA2GF_MOUSE Q9QZT4 CHEMBL5361 Group IIF Secretory Phospholipase A2, Mouse 5
PA2GA_RABIT P14422 CHEMBL5481 Phospholipase A2, Membrane Associated, Rabit 4
PA2GA_RAT P14423 CHEMBL3686 Phospholipase A2 Group IIA, Rat 4