ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (198)
Reactome (0)
Related By:
Pathway (0)
Organism (5)
Gene (1)
Org. Clust. (5)
ChEMBL (55)
Rings (12)

Cyclooxygenase-1, Sheep (198 Compounds)

Swissprot:: PGH1_SHEEP
Stitch:: PGH1_SHEEP
UniProt:: P05979
ChEMBL:: CHEMBL2949
PDB:: 1CQE (DOCK); 1DIY (DOCK); 1DJJ (DOCK); 1EBV (DOCK); 1EQG (DOCK); 1EQH (DOCK); 1FE2 (DOCK); 1HT5 (DOCK); 1HT8 (DOCK); 1IGX (DOCK); 1IGZ (DOCK); 1PGE (DOCK); 1PGF (DOCK); 1PGG (DOCK); 1PRH (DOCK); 1PTH (DOCK); 1Q4G (DOCK); 1U67 (DOCK); 2AYL (DOCK); 2OYE (DOCK); 2OYU (DOCK); 3KK6 (DOCK); 3N8V (DOCK); 3N8W (DOCK); 3N8X (DOCK); 3N8Y (DOCK); 3N8Z (DOCK); PTGS1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	198	36	21	23
Binding ≤ 1μM	89	14	9	14

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
PGH1_BOVIN	O62664	CHEMBL2860	Cyclooxygenase-1, Bovin	100	16	12	12
PGH1_HUMAN	P23219	CHEMBL221	Cyclooxygenase-1, Human	969	95	65	44
PGH1_MOUSE	P22437	CHEMBL2649	Cyclooxygenase-1, Mouse	37	7	3	3
PGH1_RABIT	O97554	CHEMBL3334	Cyclooxygenase-1, Rabit	9	1	1	1
PGH1_RAT	Q63921	CHEMBL4042	Cyclooxygenase-1, Rat	252	34	20	18

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
PGH2_SHEEP	P79208	CHEMBL4102	Cyclooxygenase-2, Sheep	284	34	17	15

Clustered By Gene (0)

Clustered By Organism (5)

Code	Description	Substances	Purchasable	Natural	In Man
PGH1-1-E	Cyclooxygenase-1 (cluster #1 Of 6), Eukaryotic	834	44	17	19
PGH1-2-E	Cyclooxygenase-1 (cluster #2 Of 6), Eukaryotic	351	70	53	38
PGH1-3-E	Cyclooxygenase-1 (cluster #3 Of 6), Eukaryotic	70	17	5	3
PGH1-4-E	Cyclooxygenase-1 (cluster #4 Of 6), Eukaryotic	47	7	6	3
PGH1-5-E	Cyclooxygenase-1 (cluster #5 Of 6), Eukaryotic	108	5	6	0
PGH1-6-E	Cyclooxygenase-1 (cluster #6 Of 6), Eukaryotic	61	7	6	7

Uniprot	Swissprot	Chembl	Description	Number Shared
PGH2_SHEEP	P79208	CHEMBL4102	Cyclooxygenase-2, Sheep	79
PGH2_HUMAN	P35354	CHEMBL230	Cyclooxygenase-2, Human	74
PGH1_HUMAN	P23219	CHEMBL221	Cyclooxygenase-1, Human	30
PGH2_MOUSE	Q05769	CHEMBL4321	Cyclooxygenase-2, Mouse	24
PGH1_RAT	Q63921	CHEMBL4042	Cyclooxygenase-1, Rat	12
PGH2_RAT	P35355	CHEMBL2977	Cyclooxygenase-2, Rat	11
LOX1_SOYBN	P08170	CHEMBL4586	Seed Lipoxygenase-1, Soybn	8
LOX5_HUMAN	P09917	CHEMBL215	Arachidonate 5-lipoxygenase, Human	8
O49150_SOLTU	O49150	CHEMBL3317	5-lipoxygenase, Soltu	8
CAH12_HUMAN	O43570	CHEMBL3242	Carbonic Anhydrase XII, Human	6
CAH2_HUMAN	P00918	CHEMBL205	Carbonic Anhydrase II, Human	6
CAH5A_HUMAN	P35218	CHEMBL4789	Carbonic Anhydrase VA, Human	6
CAH5B_HUMAN	Q9Y2D0	CHEMBL3969	Carbonic Anhydrase VB, Human	6
LOX5_RAT	P12527	CHEMBL312	Arachidonate 5-lipoxygenase, Rat	6
PGH1_BOVIN	O62664	CHEMBL2860	Cyclooxygenase-1, Bovin	6
CAH15_MOUSE	Q99N23	CHEMBL5973	Carbonic Anhydrase 15, Mouse	5
CAH4_HUMAN	P22748	CHEMBL3729	Carbonic Anhydrase IV, Human	5
CAH6_HUMAN	P23280	CHEMBL3025	Carbonic Anhydrase VI, Human	5
CAH7_HUMAN	P43166	CHEMBL2326	Carbonic Anhydrase VII, Human	5
CAH9_HUMAN	Q16790	CHEMBL3594	Carbonic Anhydrase IX, Human	5
CAH1_HUMAN	P00915	CHEMBL261	Carbonic Anhydrase I, Human	4
CAH3_HUMAN	P07451	CHEMBL2885	Carbonic Anhydrase III, Human	4
PGH2_BOVIN	O62698	CHEMBL3331	Cyclooxygenase-2, Bovin	4
FABPL_RAT	P02692	CHEMBL5738	Fatty Acid-binding Protein, Liver, Rat	3
IL8_HUMAN	P10145	CHEMBL2157	Interleukin-8, Human	3
AK1C3_HUMAN	P42330	CHEMBL4681	Aldo-keto-reductase Family 1 Member C3, Human	2
ALBU_BOVIN	P02769	CHEMBL3728	Serum Albumin, Bovin	2
CAH13_HUMAN	Q8N1Q1	CHEMBL3912	Carbonic Anhydrase XIII, Human	2
CAH14_HUMAN	Q9ULX7	CHEMBL3510	Carbonic Anhydrase XIV, Human	2
GPR44_HUMAN	Q9Y5Y4	CHEMBL5071	G Protein-coupled Receptor 44, Human	2
PGH1_MOUSE	P22437	CHEMBL2649	Cyclooxygenase-1, Mouse	2
S22A6_MOUSE	Q8VC69	CHEMBL5653	Solute Carrier Family 22 Member 6, Mouse	2
S22AK_MOUSE	Q80UJ1	CHEMBL5269	Solute Carrier Family 22 Member 20, Mouse	2
AHR_RABIT	O02747	CHEMBL4725	Aryl Hydrocarbon Receptor, Rabit	1
ALDR_HUMAN	P15121	CHEMBL1900	Aldose Reductase, Human	1
B5SU02_9CNID	B5SU02	CHEMBL1075028	Alpha Carbonic Anhydrase, 9cnid	1
C0IX24_9CNID	C0IX24	CHEMBL1649055	Carbonic Anhydrase, 9cnid	1
CAH4_BOVIN	Q95323	CHEMBL281	Carbonic Anhydrase IV, Bovin	1
CAH_METTE	P40881	CHEMBL3932	Carbonic Anhydrase, Mette	1
CAN_YEAST	P53615	CHEMBL5931	Carbonic Anhydrase, Yeast	1
CISD1_HUMAN	Q9NZ45	CHEMBL1795168	CDGSH Iron-sulfur Domain-containing Protein 1, Human	1
CLTR2_HUMAN	Q9NS75	CHEMBL4330	Cysteinyl Leukotriene Receptor 2, Human	1
COX2_SHEEP	O78750	CHEMBL1250404	Cytochrome C Oxidase Subunit 2, Sheep	1
CXCR1_HUMAN	P25024	CHEMBL4029	Interleukin-8 Receptor A, Human	1
CYNT_MYCTU	O53573	CHEMBL6068	Carbonic Anhydrase, Myctu	1
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	1
LIPS_RAT	P15304	CHEMBL5582	Hormone-sensitive Lipase, Rat	1
LT4R1_HUMAN	Q15722	CHEMBL3911	Leukotriene B4 Receptor 1, Human	1
MK14_HUMAN	Q16539	CHEMBL260	MAP Kinase P38 Alpha, Human	1
NQO2_HUMAN	P16083	CHEMBL3959	Quinone Reductase 2, Human	1
PTGDS_MOUSE	O09114	CHEMBL4334	Prostaglandin-H2 D-isomerase, Mouse	1
Q2PCB5_DICLA	Q2PCB5	CHEMBL1795125	Carbonic Anhydrase, Dicla	1
Q5AJ71_CANAL	Q5AJ71	CHEMBL5337	Carbonic Anhydrase, Canal	1
Q8HZR1_CANFA	Q8HZR1	CHEMBL4133	Cyclooxygenase-1, Canine	1
Q8SPQ9_CANFA	Q8SPQ9	CHEMBL4033	Cyclooxygenase-2, Canine	1