UCSF

Prostanoid IP Receptor, Human (165 Compounds)

Swissprot:
PI2R_HUMAN
Stitch:
PI2R_HUMAN
UniProt:
P43119
ChEMBL:
CHEMBL1995
Reactome:
REACT_19327
REACT_23946
REACT_18425
PDB:
PTGIR

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 165 10 7 7
Binding ≤ 1μM 101 9 6 6
Functional ≤ 10μM 41 4 2 2
Uniprot Swissprot Chembl Description Number Shared
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 1
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 1
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 5
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 4
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 16
PE2R2_HUMAN P43116 CHEMBL1881 Prostanoid EP2 Receptor, Human 11
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 12

Prostanoid ligand receptors

Uniprot Swissprot Chembl Description Number Shared
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 1
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 16
PE2R1_HUMAN P34995 CHEMBL1811 Prostanoid EP1 Receptor, Human 9
PE2R2_HUMAN P43116 CHEMBL1881 Prostanoid EP2 Receptor, Human 11
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 16
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 12
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP Receptor, Human 5
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 31

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PI2R-1-E Prostanoid IP Receptor (cluster #1 Of 2), Eukaryotic 157 5 3 3
PI2R-2-E Prostanoid IP Receptor (cluster #2 Of 2), Eukaryotic 12 5 4 4
Uniprot Swissprot Chembl Description Number Shared
PD2R_MOUSE P70263 CHEMBL3933 Prostanoid DP Receptor, Mouse 33
PE2R2_MOUSE Q62053 CHEMBL2488 Prostanoid EP2 Receptor, Mouse 28
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 25
PE2R3_MOUSE P30557 CHEMBL4336 Prostanoid EP3 Receptor, Mouse 20
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 16
PE2R1_MOUSE P35375 CHEMBL2181 Prostanoid EP1 Receptor, Mouse 15
PE2R4_MOUSE P32240 CHEMBL2489 Prostanoid EP4 Receptor, Mouse 14
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 13
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 12
PE2R2_HUMAN P43116 CHEMBL1881 Prostanoid EP2 Receptor, Human 11
PE2R1_HUMAN P34995 CHEMBL1811 Prostanoid EP1 Receptor, Human 9
PF2R_MOUSE P43117 CHEMBL5000 Prostaglandin F2-alpha Receptor, Mouse 8
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 5
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 5
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 5
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP Receptor, Human 5
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 4
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 4
PI2R_RAT P43253 CHEMBL3322 Prostanoid IP Receptor, Rat 2
Z50587 Z50587 CHEMBL372 Homo Sapiens 2
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 1
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 1
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 1
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 1
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 1
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 1
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 1
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 1
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 1
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 1
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 1
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 1
TYPH_HUMAN P19971 CHEMBL3106 Thymidine Phosphorylase, Human 1
Z50588 Z50588 CHEMBL373 Canis Familiaris 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1