UCSF

Retinoic Acid Receptor Gamma, Human (231 Compounds)

Swissprot:
RARG_HUMAN
Stitch:
RARG_HUMAN
UniProt:
P13631
ChEMBL:
CHEMBL2003
Reactome:
REACT_15525
PDB:
1EXA (DOCK)
1EXX (DOCK)
1FCX (DOCK)
1FCY (DOCK)
1FCZ (DOCK)
1FD0 (DOCK)
2LBD (DOCK)
3LBD (DOCK)
4LBD (DOCK)
RARG

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 231 18 10 13
Binding ≤ 1μM 189 14 7 10
Functional ≤ 10μM 37 8 6 5

Reactome Network (1)

Reactome ID Description Species
REACT_15525 Nuclear Receptor transcription pathway Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
PPARA_HUMAN Q07869 CHEMBL239 Peroxisome Proliferator-activated Receptor Alpha, Human 2
PPARD_HUMAN Q03181 CHEMBL3979 Peroxisome Proliferator-activated Receptor Delta, Human 2
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 21
RARA_HUMAN P10276 CHEMBL2055 Retinoic Acid Receptor Alpha, Human 175
RARB_HUMAN P10826 CHEMBL2008 Retinoic Acid Receptor Beta, Human 207
RXRA_HUMAN P19793 CHEMBL2061 Retinoid X Receptor Alpha, Human 78
RXRB_HUMAN P28702 CHEMBL1870 Retinoid X Receptor Beta, Human 30
RXRG_HUMAN P48443 CHEMBL2004 Retinoid X Receptor Gamma, Human 33
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
RARG_MOUSE P18911 CHEMBL4177 Retinoic Acid Receptor Gamma, Mouse 17 3 2 2

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
RARG-1-E Retinoic Acid Receptor Gamma (cluster #1 Of 2), Eukaryotic 224 15 8 11
RARG-2-E Retinoic Acid Receptor Gamma (cluster #2 Of 2), Eukaryotic 21 3 2 2
Uniprot Swissprot Chembl Description Number Shared
RARB_HUMAN P10826 CHEMBL2008 Retinoic Acid Receptor Beta, Human 207
RARA_HUMAN P10276 CHEMBL2055 Retinoic Acid Receptor Alpha, Human 175
RXRA_HUMAN P19793 CHEMBL2061 Retinoid X Receptor Alpha, Human 78
RXRG_HUMAN P48443 CHEMBL2004 Retinoid X Receptor Gamma, Human 33
RXRB_HUMAN P28702 CHEMBL1870 Retinoid X Receptor Beta, Human 30
RXRB_MOUSE P28704 CHEMBL4047 Retinoid X Receptor Beta, Mouse 20
RXRG_MOUSE P28705 CHEMBL4402 Retinoid X Receptor Gamma, Mouse 14
RXRA_MOUSE P28700 CHEMBL3084 Retinoid X Receptor Alpha, Mouse 7
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 7
RXRA_RAT Q05343 CHEMBL4431 Retinoid X Receptor Alpha, Rat 6
Z50594 Z50594 CHEMBL375 Mus Musculus 6
D3ZWV0_RAT D3ZWV0 CHEMBL2630 Retinoic Acid Receptor Gamma, Rat 5
PPARG_RAT O88275 CHEMBL4797 Peroxisome Proliferator-activated Receptor Gamma, Rat 4
RARA_MOUSE P11416 CHEMBL2792 Retinoic Acid Receptor Alpha, Mouse 4
RARB_MOUSE P22605 CHEMBL3266 Retinoic Acid Receptor Beta, Mouse 4
Q499N1_RAT Q499N1 CHEMBL2269 Retinoic Acid Receptor Alpha, Rat 3
RARG_MOUSE P18911 CHEMBL4177 Retinoic Acid Receptor Gamma, Mouse 3
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 2
PPARA_HUMAN Q07869 CHEMBL239 Peroxisome Proliferator-activated Receptor Alpha, Human 2
PPARD_HUMAN Q03181 CHEMBL3979 Peroxisome Proliferator-activated Receptor Delta, Human 2
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 2
RXRB_RAT P49743 CHEMBL2805 Retinoid X Receptor Beta, Rat 2
RXRG_RAT Q5BJR8 CHEMBL4277 Retinoid X Receptor Gamma, Rat 2
Z80135 Z80135 CHEMBL614296 F9 2
RABP1_CHICK P40220 CHEMBL4945 Cellular Retinoic Acid-binding Protein I, Chick 1
RABP1_MOUSE P62965 CHEMBL3208 Cellular Retinoic Acid-binding Protein I, Mouse 1
RABP2_MOUSE P22935 CHEMBL4172 Cellular Retinoic Acid-binding Protein II, Mouse 1
Z50518 Z50518 CHEMBL613124 Human Herpesvirus 4 1
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 1
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 1
Z80377 Z80377 CHEMBL614228 PaCa2 1
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 1
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast Adenocarcinoma) 1
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 1
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 1