RENI_HUMAN - Renin, Human | ZINC Is Not Commercial - A database of commercially-available compounds

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	2,872	3	5	12
Binding ≤ 1μM	2,517	3	5	11
Functional ≤ 10μM	54	0	0	1

Reactome ID	Description	Species
REACT_147707	Metabolism of Angiotensinogen to Angiotensins	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
ACE2_HUMAN	Q9BYF1	CHEMBL3736	Angiotensin-converting Enzyme 2, Human	2
ACE_HUMAN	P12821	CHEMBL1808	Angiotensin-converting Enzyme, Human	4
AMPE_HUMAN	Q07075	CHEMBL3439	Aminopeptidase A, Human	1
AMPN_HUMAN	P15144	CHEMBL1907	Aminopeptidase N, Human	1
CATD_HUMAN	P07339	CHEMBL2581	Cathepsin D, Human	62

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
RENI_CALJA	Q9TSZ1	CHEMBL6056	Renin, Calja	79	1	1	1
RENI_MACMU	Q6DLW5	CHEMBL1287631	Renin, Macmu	2	0	0	0
RENI_RAT	P08424	CHEMBL2322	Renin, Rat	34	1	1	2

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
CATD_BOVIN	P80209	CHEMBL4106	Cathepsin D, Bovin	92
RENI_CALJA	Q9TSZ1	CHEMBL6056	Renin, Calja	79
CATD_HUMAN	P07339	CHEMBL2581	Cathepsin D, Human	62
PEPA_PIG	P00791	CHEMBL2714	Pepsin A, Pig	43
RENI_RAT	P08424	CHEMBL2322	Renin, Rat	33
CATE_HUMAN	P14091	CHEMBL3092	Cathepsin E, Human	26
BACE1_HUMAN	P56817	CHEMBL4822	Beta-secretase 1, Human	23
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	17
PEPC_HUMAN	P20142	CHEMBL2136	Pepsinogen C, Human	16
BACE2_HUMAN	Q9Y5Z0	CHEMBL2525	Beta Secretase 2, Human	15
PEPA_HUMAN	P00790	CHEMBL3295	Pepsin A, Human	13
ECE1_RAT	P42893	CHEMBL2676	Endothelin-converting Enzyme 1, Rat	7
Q72874_9HIV1	Q72874	CHEMBL243	Human Immunodeficiency Virus Type 1 Protease, 9hiv1	7
RENI1_MOUSE	P06281	CHEMBL2615	Renin, Mouse	5
ACE_HUMAN	P12821	CHEMBL1808	Angiotensin-converting Enzyme, Human	4
ACE_RAT	P47820	CHEMBL2625	Angiotensin-converting Enzyme, Rat	3
ACE2_HUMAN	Q9BYF1	CHEMBL3736	Angiotensin-converting Enzyme 2, Human	2
ACE_RABIT	P12822	CHEMBL4074	Angiotensin-converting Enzyme, Rabit	2
B7ZW62_HUMAN	B7ZW62	CHEMBL3447	Pepsinogen A5, Human	2
Q4U254_9ENTO	Q4U254	CHEMBL2857	Human Rhinovirus A Protease, 9ento	2
A4_HUMAN	P05067	CHEMBL2487	Beta Amyloid A4 Protein, Human	1
ACE2_RAT	Q5EGZ1	CHEMBL2311	Angiotensin-converting Enzyme-related Carboxypeptidase, Rat	1
ADAM9_HUMAN	Q13443	CHEMBL5982	ADAM9, Human	1
AMPB_HUMAN	Q9H4A4	CHEMBL2432	Aminopeptidase B, Human	1
AMPE_HUMAN	Q07075	CHEMBL3439	Aminopeptidase A, Human	1
AMPN_HUMAN	P15144	CHEMBL1907	Aminopeptidase N, Human	1
CATB_HUMAN	P07858	CHEMBL4072	Cathepsin B, Human	1
CATL1_HUMAN	P07711	CHEMBL3837	Cathepsin L, Human	1
CATS_HUMAN	P25774	CHEMBL2954	Cathepsin S, Human	1
CTRA_BOVIN	P00766	CHEMBL3314	Alpha-chymotrypsin, Bovin	1
DAPE_HAEIN	P44514	CHEMBL1075192	Succinyl-diaminopimelate Desuccinylase, Haein	1
LKHA4_HUMAN	P09960	CHEMBL4618	Leukotriene A4 Hydrolase, Human	1
PLM2_PLAFA	P46925	CHEMBL4414	Plasmepsin 2, Plafa	1
Q7M3D2_RABIT	Q7M3D2	CHEMBL1287632	Renin, Rabit	1
Q95WR6_LEIDO	Q95WR6	CHEMBL4751	Cysteine Protease, Leido	1
THRB_HUMAN	P00734	CHEMBL204	Thrombin, Human	1