UCSF

Ribonucleoside-diphosphate Reductase M2 Chain, Human (45 Compounds)

Swissprot:
RIR2_HUMAN
Stitch:
RIR2_HUMAN
UniProt:
P31350
ChEMBL:
CHEMBL1954
Reactome:
REACT_471
REACT_683
REACT_21330
PDB:
2UW2 (DOCK)
3OLJ (DOCK)
RRM2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 45 1 0 0
Binding ≤ 1μM 28 1 0 0
Functional ≤ 10μM 0 0 0 0

Reactome Network (3)

Reactome ID Description Species
REACT_471 E2F mediated regulation of DNA replication Homo sapiens
REACT_683 G1/S-Specific Transcription Homo sapiens
REACT_21330 Synthesis and interconversion of nucleotide di- and triphosphates Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
RIR1_HUMAN P23921 CHEMBL1830 Ribonucleoside-diphosphate Reductase M1 Chain, Human 34
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
RIR2_HHV1K P06474 CHEMBL3566 Ribonucleoside-diphosphate Reductase Small Chain, Hhv1k 6 0 0 0
RIR2_HHV23 P69520 CHEMBL2418 Ribonucleoside-diphosphate Reductase Small Chain, Hhv23 6 0 0 0
RIR2_MOUSE P11157 CHEMBL3527 Ribonucleoside-diphosphate Reductase M2 Chain, Mouse 4 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
RIR1_HUMAN P23921 CHEMBL1830 Ribonucleoside-diphosphate Reductase M1 Chain, Human 34 0 0 0

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
RIR2-1-E Ribonucleoside-diphosphate Reductase Small Chain (cluster #1 Of 3), Eukaryotic 4 0 0 0
RIR2-1-V Ribonucleoside-diphosphate Reductase Small Chain (cluster #1 Of 1), Viral 12 0 0 0
RIR2-2-E Ribonucleoside-diphosphate Reductase Small Chain (cluster #2 Of 3), Eukaryotic 34 0 0 0
RIR2-3-E Ribonucleoside-diphosphate Reductase Small Chain (cluster #3 Of 3), Eukaryotic 11 1 0 0
Uniprot Swissprot Chembl Description Number Shared
RIR1_HUMAN P23921 CHEMBL1830 Ribonucleoside-diphosphate Reductase M1 Chain, Human 34
RIR1_HHV11 P08543 CHEMBL3840 Ribonucleoside-diphosphate Reductase Large Chain, Hhv11 11
RIR2_HHV1K P06474 CHEMBL3566 Ribonucleoside-diphosphate Reductase Small Chain, Hhv1k 6