UCSF

Rho-associated Protein Kinase 2, Human (636 Compounds)

Swissprot:
ROCK2_HUMAN
Stitch:
ROCK2_HUMAN
UniProt:
O75116
ChEMBL:
CHEMBL2973
Reactome:
REACT_228063
REACT_228085
REACT_18407
REACT_19277
REACT_228166
PDB:
ROCK2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 636 13 3 8
Binding ≤ 1μM 593 12 2 7

Reactome Network (5)

Reactome ID Description Species
REACT_228063 EPHA-mediated growth cone collapse Homo sapiens
REACT_228085 EPHB-mediated forward signaling Homo sapiens
REACT_18407 G alpha (12/13) signalling events Homo sapiens
REACT_19277 Sema4D induced cell migration and growth-cone collapse Homo sapiens
REACT_228166 VEGFA-VEGFR2 Pathway Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
EPHA3_HUMAN P29320 CHEMBL4954 Ephrin Type-A Receptor 3, Human 1
EPHA5_HUMAN P54756 CHEMBL3987 Ephrin Type-A Receptor 5, Human 1
EPHA6_HUMAN Q9UF33 CHEMBL4526 Ephrin Type-A Receptor 6, Human 1
EPHA7_HUMAN Q15375 CHEMBL4602 Ephrin Type-A Receptor 7, Human 1
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 1
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 162
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 6
YES_HUMAN P07947 CHEMBL2073 Tyrosine-protein Kinase YES, Human 1

EPHB-mediated forward signaling

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 6
EPHB1_HUMAN P54762 CHEMBL5072 Ephrin Type-B Receptor 1, Human 1
EPHB4_HUMAN P54760 CHEMBL5147 Ephrin Type-B Receptor 4, Human 1
EPHB6_HUMAN O15197 CHEMBL5836 Ephrin Type-B Receptor 6, Human 1
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
LIMK1_HUMAN P53667 CHEMBL3836 LIM Domain Kinase 1, Human 5
LIMK2_HUMAN P53671 CHEMBL5932 LIM Domain Kinase 2, Human 4
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 1
PAK1_HUMAN Q13153 CHEMBL4600 Serine/threonine-protein Kinase PAK 1, Human 1
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 162
YES_HUMAN P07947 CHEMBL2073 Tyrosine-protein Kinase YES, Human 1

G alpha (12/13) signalling events

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 6
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 162

Sema4D induced cell migration and growth-cone collapse

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 6
LIMK1_HUMAN P53667 CHEMBL3836 LIM Domain Kinase 1, Human 5
LIMK2_HUMAN P53671 CHEMBL5932 LIM Domain Kinase 2, Human 4
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 162

VEGFA-VEGFR2 Pathway

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 6
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 4
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 2
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 2
MAPK2_HUMAN P49137 CHEMBL2208 MAP Kinase-activated Protein Kinase 2, Human 1
MAPK3_HUMAN Q16644 CHEMBL4670 MAP Kinase-activated Protein Kinase 3, Human 1
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 1
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 162
UFO_HUMAN P30530 CHEMBL4895 Tyrosine-protein Kinase Receptor UFO, Human 1
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 6
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ROCK2_RAT Q62868 CHEMBL5490 Rho-associated Protein Kinase 2, Rat 3 3 1 3
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 416 21 3 8

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
ROCK2-1-E Rho-associated Protein Kinase 2 (cluster #1 Of 2), Eukaryotic 224 7 2 6
ROCK2-2-E Rho-associated Protein Kinase 2 (cluster #2 Of 2), Eukaryotic 423 7 1 3
Uniprot Swissprot Chembl Description Number Shared
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 162
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 42
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 29
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 19
PKN2_HUMAN Q16513 CHEMBL3032 Protein Kinase N2, Human 18
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 17
MRCKA_HUMAN Q5VT25 CHEMBL4516 Serine/threonine-protein Kinase MRCK-A, Human 14
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 12
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 6
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 6
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 5
KS6A5_HUMAN O75582 CHEMBL4237 Ribosomal Protein S6 Kinase Alpha 5, Human 5
LIMK1_HUMAN P53667 CHEMBL3836 LIM Domain Kinase 1, Human 5
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 4
LIMK2_HUMAN P53671 CHEMBL5932 LIM Domain Kinase 2, Human 4
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 3
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 3
BLK_HUMAN P51451 CHEMBL2250 Tyrosine-protein Kinase BLK, Human 3
CCL2_HUMAN P13500 CHEMBL1649052 C-C Motif Chemokine 2, Human 3
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 3
CHK1_HUMAN O14757 CHEMBL4630 Serine/threonine-protein Kinase Chk1, Human 3
DYR1A_HUMAN Q13627 CHEMBL2292 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Human 3
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 3
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 3
KGP1_HUMAN Q13976 CHEMBL4273 CGMP-dependent Protein Kinase 1 Beta, Human 3
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 3
KS6A3_HUMAN P51812 CHEMBL2345 Ribosomal Protein S6 Kinase Alpha 3, Human 3
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 3
MK10_HUMAN P53779 CHEMBL2637 C-Jun N-terminal Kinase 3, Human 3
PAK4_HUMAN O96013 CHEMBL4482 Serine/threonine-protein Kinase PAK 4, Human 3
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 3
PKN1_HUMAN Q16512 CHEMBL3384 Protein Kinase N1, Human 3
ROCK2_RAT Q62868 CHEMBL5490 Rho-associated Protein Kinase 2, Rat 3
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 3
STK3_HUMAN Q13188 CHEMBL4708 Serine/threonine-protein Kinase MST2, Human 3
TYK2_HUMAN P29597 CHEMBL3553 Tyrosine-protein Kinase TYK2, Human 3
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 2
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 2
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 2
CHK2_HUMAN O96017 CHEMBL2527 Serine/threonine-protein Kinase Chk2, Human 2
CSF1R_HUMAN P07333 CHEMBL1844 Macrophage Colony Stimulating Factor Receptor, Human 2
DAPK3_HUMAN O43293 CHEMBL2468 Death-associated Protein Kinase 3, Human 2
DCLK3_HUMAN Q9C098 CHEMBL6123 Serine/threonine-protein Kinase DCLK3, Human 2
DYRK2_HUMAN Q92630 CHEMBL4376 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 2, Human 2
E2AK2_HUMAN P19525 CHEMBL5785 Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human 2
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 2
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 2
IKKA_HUMAN O15111 CHEMBL3476 Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, Human 2
JAK1_HUMAN P23458 CHEMBL2835 Tyrosine-protein Kinase JAK1, Human 2
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 2
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 2
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 2
KCC1A_HUMAN Q14012 CHEMBL2493 CaM Kinase I Alpha, Human 2
KGP2_HUMAN Q13237 CHEMBL2896 CGMP-dependent Protein Kinase 2, Human 2
KPCD2_HUMAN Q9BZL6 CHEMBL4900 Serine/threonine-protein Kinase D2, Human 2
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 2
KS6A2_HUMAN Q15349 CHEMBL3906 Ribosomal Protein S6 Kinase Alpha 2, Human 2
KS6A6_HUMAN Q9UK32 CHEMBL4924 Ribosomal Protein S6 Kinase Alpha 6, Human 2
KS6B1_HUMAN P23443 CHEMBL4501 Ribosomal Protein S6 Kinase 1, Human 2
MARK3_HUMAN P27448 CHEMBL5600 Serine/threonine-protein Kinase C-TAK1, Human 2
MK09_HUMAN P45984 CHEMBL4179 C-Jun N-terminal Kinase 2, Human 2
MYLK_HUMAN Q15746 CHEMBL2428 Myosin Light Chain Kinase, Smooth Muscle, Human 2
NUAK2_HUMAN Q9H093 CHEMBL5698 NUAK Family SNF1-like Kinase 2, Human 2
PIM3_HUMAN Q86V86 CHEMBL5407 Serine/threonine-protein Kinase PIM3, Human 2
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 2
PRKX_HUMAN P51817 CHEMBL5818 Serine/threonine-protein Kinase PRKX, Human 2
SGK1_HUMAN O00141 CHEMBL2343 Serine/threonine-protein Kinase Sgk1, Human 2
TNK1_HUMAN Q13470 CHEMBL5334 Non-receptor Tyrosine-protein Kinase TNK1, Human 2
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 2
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 2
AAK1_HUMAN Q2M2I8 CHEMBL3830 Adaptor-associated Kinase, Human 1
AAPK1_HUMAN Q13131 CHEMBL4045 AMP-activated Protein Kinase, Alpha-1 Subunit, Human 1
AAPK2_HUMAN P54646 CHEMBL2116 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 1
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 1
ABL2_HUMAN P42684 CHEMBL4014 Tyrosine-protein Kinase ABL2, Human 1
ACK1_HUMAN Q07912 CHEMBL4599 Tyrosine Kinase Non-receptor Protein 2, Human 1
ALK_HUMAN Q9UM73 CHEMBL4247 ALK Tyrosine Kinase Receptor, Human 1
ANKK1_HUMAN Q8NFD2 CHEMBL5547 Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human 1
AURKC_HUMAN Q9UQB9 CHEMBL3935 Serine/threonine-protein Kinase Aurora-C, Human 1
BMP2K_HUMAN Q9NSY1 CHEMBL4522 BMP-2-inducible Protein Kinase, Human 1
BMPR2_HUMAN Q13873 CHEMBL5467 Bone Morphogenetic Protein Receptor Type-2, Human 1
BRD4_HUMAN O60885 CHEMBL1163125 Bromodomain-containing Protein 4, Human 1
BRSK1_HUMAN Q8TDC3 CHEMBL5650 BR Serine/threonine-protein Kinase 1, Human 1
BRSK2_HUMAN Q8IWQ3 CHEMBL4574 BR Serine/threonine-protein Kinase 2, Human 1
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 1
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1
CDK14_HUMAN O94921 CHEMBL6162 Serine/threonine-protein Kinase PFTAIRE-1, Human 1
CDK16_HUMAN Q00536 CHEMBL4597 Serine/threonine-protein Kinase PCTAIRE-1, Human 1
CDK17_HUMAN Q00537 CHEMBL5790 Serine/threonine-protein Kinase PCTAIRE-2, Human 1
CDK18_HUMAN Q07002 CHEMBL5316 Serine/threonine-protein Kinase PCTAIRE-3, Human 1
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 1
CDK7_HUMAN P50613 CHEMBL3055 Cyclin-dependent Kinase 7, Human 1
CDKL2_HUMAN Q92772 CHEMBL5728 Cyclin-dependent Kinase-like 2, Human 1
CLK1_HUMAN P49759 CHEMBL4224 Dual Specificty Protein Kinase CLK1, Human 1
CLK2_HUMAN P49760 CHEMBL4225 Dual Specificity Protein Kinase CLK2, Human 1
CLK4_HUMAN Q9HAZ1 CHEMBL4203 Dual Specificity Protein Kinase CLK4, Human 1
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 1
CSK22_HUMAN P19784 CHEMBL4070 Casein Kinase II Alpha (prime), Human 1
CTRO_HUMAN O14578 CHEMBL5579 Citron Rho-interacting Kinase, Human 1
DAPK1_HUMAN P53355 CHEMBL2558 Death-associated Protein Kinase 1, Human 1
DAPK2_HUMAN Q9UIK4 CHEMBL3123 Death-associated Protein Kinase 2, Human 1
DCLK1_HUMAN O15075 CHEMBL5683 Serine/threonine-protein Kinase DCLK1, Human 1
DCLK2_HUMAN Q8N568 CHEMBL5519 Serine/threonine-protein Kinase DCLK2, Human 1
DDR1_HUMAN Q08345 CHEMBL5319 Epithelial Discoidin Domain-containing Receptor 1, Human 1
DLK1_HUMAN P80370 CHEMBL5671 Protein Delta Homolog 1, Human 1
DYR1B_HUMAN Q9Y463 CHEMBL5543 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human 1
E2AK4_HUMAN Q9P2K8 CHEMBL5358 Eukaryotic Translation Initiation Factor 2-alpha Kinase 4, Human 1
EPHA3_HUMAN P29320 CHEMBL4954 Ephrin Type-A Receptor 3, Human 1
EPHA5_HUMAN P54756 CHEMBL3987 Ephrin Type-A Receptor 5, Human 1
EPHA6_HUMAN Q9UF33 CHEMBL4526 Ephrin Type-A Receptor 6, Human 1
EPHA7_HUMAN Q15375 CHEMBL4602 Ephrin Type-A Receptor 7, Human 1
EPHB1_HUMAN P54762 CHEMBL5072 Ephrin Type-B Receptor 1, Human 1
EPHB4_HUMAN P54760 CHEMBL5147 Ephrin Type-B Receptor 4, Human 1
EPHB6_HUMAN O15197 CHEMBL5836 Ephrin Type-B Receptor 6, Human 1
ERN1_HUMAN O75460 CHEMBL1163101 Serine/threonine-protein Kinase/endoribonuclease IRE1, Human 1
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 1
FER_HUMAN P16591 CHEMBL3982 Tyrosine-protein Kinase FER, Human 1
FES_HUMAN P07332 CHEMBL5455 Tyrosine-protein Kinase FES, Human 1
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 1
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 1
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 1
FGR_HUMAN P09769 CHEMBL4454 Tyrosine-protein Kinase FGR, Human 1
FRK_HUMAN P42685 CHEMBL4223 Tyrosine-protein Kinase FRK, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
GAK_HUMAN O14976 CHEMBL4355 Serine/threonine-protein Kinase GAK, Human 1
GRK4_HUMAN P32298 CHEMBL5861 G Protein-coupled Receptor Kinase 4, Human 1
GRK7_HUMAN Q8WTQ7 CHEMBL1075133 G Protein-coupled Receptor Kinase 7, Human 1
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 1
HCK_HUMAN P08631 CHEMBL3234 Tyrosine-protein Kinase HCK, Human 1
HIPK2_HUMAN Q9H2X6 CHEMBL4576 Homeodomain-interacting Protein Kinase 2, Human 1
HIPK3_HUMAN Q9H422 CHEMBL4577 Homeodomain-interacting Protein Kinase 3, Human 1
HIPK4_HUMAN Q8NE63 CHEMBL1075167 Homeodomain-interacting Protein Kinase 4, Human 1
ICK_HUMAN Q9UPZ9 CHEMBL1163126 Serine/threonine-protein Kinase ICK, Human 1
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 1
IKKE_HUMAN Q14164 CHEMBL3529 Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human 1
INSRR_HUMAN P14616 CHEMBL5483 Insulin Receptor-related Protein, Human 1
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 1
IRAK1_HUMAN P51617 CHEMBL3357 Interleukin-1 Receptor-associated Kinase 1, Human 1
IRAK3_HUMAN Q9Y616 CHEMBL5081 Interleukin-1 Receptor-associated Kinase 3, Human 1
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 1
JAK3_MOUSE Q62137 CHEMBL5250 Tyrosine-protein Kinase JAK3, Mouse 1
KAP2_BOVIN P00515 CHEMBL3654 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Bovin 1
KAP3_BOVIN P31322 CHEMBL3280 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Bovin 1
KAPCA_BOVIN P00517 CHEMBL2654 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Bovin 1
KAPCB_BOVIN P05131 CHEMBL3279 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Bovin 1
KC1AL_HUMAN Q8N752 CHEMBL5520 Casein Kinase I Isoform Alpha-like, Human 1
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 1
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 1
KC1G1_HUMAN Q9HCP0 CHEMBL2426 Casein Kinase I Gamma 1, Human 1
KC1G2_HUMAN P78368 CHEMBL2543 Casein Kinase I Gamma 2, Human 1
KC1G3_HUMAN Q9Y6M4 CHEMBL5084 Casein Kinase I Isoform Gamma-3, Human 1
KCC1D_HUMAN Q8IU85 CHEMBL5073 CaM Kinase I Delta, Human 1
KCC1G_HUMAN Q96NX5 CHEMBL5258 CaM Kinase I Gamma, Human 1
KCC2A_HUMAN Q9UQM7 CHEMBL4147 CaM Kinase II Alpha, Human 1
KCC2B_HUMAN Q13554 CHEMBL4121 CaM Kinase II Beta, Human 1
KCC2D_HUMAN Q13557 CHEMBL2801 CaM Kinase II Delta, Human 1
KCC2G_HUMAN Q13555 CHEMBL3829 CaM Kinase II Gamma, Human 1
KCC4_HUMAN Q16566 CHEMBL2494 CaM Kinase IV, Human 1
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 1
KKCC1_HUMAN Q8N5S9 CHEMBL5256 CaM-kinase Kinase Alpha, Human 1
KKCC2_HUMAN Q96RR4 CHEMBL5284 CaM-kinase Kinase Beta, Human 1
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 1
KPCD3_HUMAN O94806 CHEMBL2595 Protein Kinase C Nu, Human 1
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 1
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 1
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 1
KS6A1_HUMAN Q15418 CHEMBL2553 Ribosomal Protein S6 Kinase Alpha 1, Human 1
KS6A4_HUMAN O75676 CHEMBL3125 Ribosomal Protein S6 Kinase Alpha 4, Human 1
LATS1_HUMAN O95835 CHEMBL6167 Serine/threonine-protein Kinase LATS1, Human 1
LATS2_HUMAN Q9NRM7 CHEMBL5907 Serine/threonine-protein Kinase LATS2, Human 1
LTK_HUMAN P29376 CHEMBL5627 Leukocyte Tyrosine Kinase Receptor, Human 1
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 1
M3K11_HUMAN Q16584 CHEMBL2708 Mitogen-activated Protein Kinase Kinase Kinase 11, Human 1
M3K13_HUMAN O43283 CHEMBL1163124 Mitogen-activated Protein Kinase Kinase Kinase 13, Human 1
M3K15_HUMAN Q6ZN16 CHEMBL1163127 Mitogen-activated Protein Kinase Kinase Kinase 15, Human 1
M3K2_HUMAN Q9Y2U5 CHEMBL5914 Mitogen-activated Protein Kinase Kinase Kinase 2, Human 1
M3K3_HUMAN Q99759 CHEMBL5970 Mitogen-activated Protein Kinase Kinase Kinase 3, Human 1
M3K4_HUMAN Q9Y6R4 CHEMBL4853 Mitogen-activated Protein Kinase Kinase Kinase 4, Human 1
M3K7_HUMAN O43318 CHEMBL5776 Mitogen-activated Protein Kinase Kinase Kinase 7, Human 1
M3K9_HUMAN P80192 CHEMBL2872 Mitogen-activated Protein Kinase Kinase Kinase 9, Human 1
M4K1_HUMAN Q92918 CHEMBL5749 Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human 1
M4K3_HUMAN Q8IVH8 CHEMBL5432 Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human 1
M4K4_HUMAN O95819 CHEMBL6166 Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human 1
M4K5_HUMAN Q9Y4K4 CHEMBL4852 Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human 1
MAPK2_HUMAN P49137 CHEMBL2208 MAP Kinase-activated Protein Kinase 2, Human 1
MAPK3_HUMAN Q16644 CHEMBL4670 MAP Kinase-activated Protein Kinase 3, Human 1
MARK1_HUMAN Q9P0L2 CHEMBL5940 Serine/threonine-protein Kinase MARK1, Human 1
MARK2_HUMAN Q7KZI7 CHEMBL3831 MAP/microtubule Affinity-regulating Kinase 2, Human 1
MARK4_HUMAN Q96L34 CHEMBL5754 MAP/microtubule Affinity-regulating Kinase 4, Human 1
MAST1_HUMAN Q9Y2H9 CHEMBL1163128 Microtubule-associated Serine/threonine-protein Kinase 1, Human 1
MELK_HUMAN Q14680 CHEMBL4578 Maternal Embryonic Leucine Zipper Kinase, Human 1
MERTK_HUMAN Q12866 CHEMBL5331 Proto-oncogene Tyrosine-protein Kinase MER, Human 1
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 1
MINK1_HUMAN Q8N4C8 CHEMBL5518 Misshapen-like Kinase 1, Human 1
MK08_HUMAN P45983 CHEMBL2276 C-Jun N-terminal Kinase 1, Human 1
MK10_RAT P49187 CHEMBL4092 C-Jun N-terminal Kinase 3, Rat 1
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 1
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 1
MP2K2_HUMAN P36507 CHEMBL2964 Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human 1
MP2K6_HUMAN P52564 CHEMBL2171 Dual Specificity Mitogen-activated Protein Kinase Kinase 6, Human 1
MST4_HUMAN Q9P289 CHEMBL5941 Serine/threonine-protein Kinase MST4, Human 1
MUSK_HUMAN O15146 CHEMBL5684 Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human 1
MYLK2_HUMAN Q9H1R3 CHEMBL2777 Myosin Light Chain Kinase 2, Human 1
MYLK4_HUMAN Q86YV6 CHEMBL5426 Myosin Light Chain Kinase Family Member 4, Human 1
MYLK_CHICK P11799 CHEMBL3062 Myosin Light Chain Kinase, Smooth Muscle, Chick 1
MYO3B_HUMAN Q8WXR4 CHEMBL5654 Myosin-IIIB, Human 1
NEK2_HUMAN P51955 CHEMBL3835 Serine/threonine-protein Kinase NEK2, Human 1
NEK7_HUMAN Q8TDX7 CHEMBL4849 Serine/threonine-protein Kinase NEK7, Human 1
NIM1_HUMAN Q8IY84 CHEMBL3542 Serine/threonine-protein Kinase NIM1, Human 1
NTRK1_HUMAN P04629 CHEMBL2815 Nerve Growth Factor Receptor Trk-A, Human 1
NTRK2_HUMAN Q16620 CHEMBL4898 Neurotrophic Tyrosine Kinase Receptor Type 2, Human 1
NTRK3_HUMAN Q16288 CHEMBL5608 NT-3 Growth Factor Receptor, Human 1
NUAK1_HUMAN O60285 CHEMBL5784 NUAK Family SNF1-like Kinase 1, Human 1
OXSR1_HUMAN O95747 CHEMBL1163104 Serine/threonine-protein Kinase OSR1, Human 1
PAK1_HUMAN Q13153 CHEMBL4600 Serine/threonine-protein Kinase PAK 1, Human 1
PAK3_HUMAN O75914 CHEMBL2999 Serine/threonine-protein Kinase PAK 3, Human 1
PAK6_HUMAN Q9NQU5 CHEMBL4311 Serine/threonine-protein Kinase PAK6, Human 1
PAK7_HUMAN Q9P286 CHEMBL4524 Serine/threonine-protein Kinase PAK7, Human 1
PDK1_HUMAN Q15118 CHEMBL4766 Pyruvate Dehydrogenase Kinase Isoform 1, Human 1
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 1
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 1
PHKG1_HUMAN Q16816 CHEMBL4004 Phosphorylase Kinase Gamma Subunit 1, Human 1
PHKG2_HUMAN P15735 CHEMBL2349 Phosphorylase Kinase Gamma Subunit 2, Human 1
PI42B_HUMAN P78356 CHEMBL5667 Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta, Human 1
PI51A_HUMAN Q99755 CHEMBL5969 Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha, Human 1
PIM2_HUMAN Q9P1W9 CHEMBL4523 Serine/threonine-protein Kinase PIM2, Human 1
PLK2_HUMAN Q9NYY3 CHEMBL5938 Serine/threonine-protein Kinase PLK2, Human 1
PRP4_HUMAN O43172 CHEMBL1163119 U4/U6 Small Nuclear Ribonucleoprotein Prp4, Human 1
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 1
RET_HUMAN P07949 CHEMBL2041 Tyrosine-protein Kinase Receptor RET, Human 1
RIOK1_HUMAN Q9BRS2 CHEMBL5975 Serine/threonine-protein Kinase RIO1, Human 1
RIOK2_HUMAN Q9BVS4 CHEMBL6000 Serine/threonine-protein Kinase RIO2, Human 1
RIOK3_HUMAN O14730 CHEMBL5659 Serine/threonine-protein Kinase RIO3, Human 1
RIPK1_HUMAN Q13546 CHEMBL5464 Receptor-interacting Serine/threonine-protein Kinase 1, Human 1
RIPK4_HUMAN P57078 CHEMBL6083 Receptor-interacting Serine/threonine-protein Kinase 4, Human 1
RK_HUMAN Q15835 CHEMBL5607 Rhodopsin Kinase, Human 1
SG110_HUMAN P0C264 CHEMBL5116 Putative Uncharacterized Serine/threonine-protein Kinase SgK110, Human 1
SIK1_HUMAN P57059 CHEMBL6082 Serine/threonine-protein Kinase SIK1, Human 1
SIK2_HUMAN Q9H0K1 CHEMBL5699 Serine/threonine-protein Kinase SIK2, Human 1
SLK_HUMAN Q9H2G2 CHEMBL4202 Serine/threonine-protein Kinase 2, Human 1
SRPK1_HUMAN Q96SB4 CHEMBL4375 Serine/threonine-protein Kinase SRPK1, Human 1
SRPK2_HUMAN P78362 CHEMBL5668 Serine/threonine-protein Kinase SRPK2, Human 1
SRPK3_HUMAN Q9UPE1 CHEMBL5415 Serine/threonine-protein Kinase SRPK3, Human 1
ST17A_HUMAN Q9UEE5 CHEMBL4525 Serine/threonine-protein Kinase 17A, Human 1
ST17B_HUMAN O94768 CHEMBL3980 Serine/threonine-protein Kinase 17B, Human 1
ST38L_HUMAN Q9Y2H1 CHEMBL4851 Serine/threonine-protein Kinase 38-like, Human 1
STK10_HUMAN O94804 CHEMBL3981 Serine/threonine-protein Kinase 10, Human 1
STK11_HUMAN Q15831 CHEMBL5606 Serine/threonine-protein Kinase 11, Human 1
STK16_HUMAN O75716 CHEMBL3938 Serine/threonine-protein Kinase 16, Human 1
STK24_HUMAN Q9Y6E0 CHEMBL5082 Serine/threonine-protein Kinase 24, Human 1
STK25_HUMAN O00506 CHEMBL5552 Serine/threonine-protein Kinase 25, Human 1
STK33_HUMAN Q9BYT3 CHEMBL6005 Serine/threonine-protein Kinase 33, Human 1
STK35_HUMAN Q8TDR2 CHEMBL5651 Serine/threonine-protein Kinase 35, Human 1
STK38_HUMAN Q15208 CHEMBL1075155 Serine/threonine-protein Kinase 38, Human 1
STK39_HUMAN Q9UEW8 CHEMBL1163108 STE20/SPS1-related Proline-alanine-rich Protein Kinase, Human 1
STK3_MOUSE Q9JI10 CHEMBL4310 Serine/threonine-protein Kinase MST2, Mouse 1
STK4_HUMAN Q13043 CHEMBL4598 Serine/threonine-protein Kinase MST1, Human 1
TAOK1_HUMAN Q7L7X3 CHEMBL5261 Serine/threonine-protein Kinase TAO1, Human 1
TAOK3_HUMAN Q9H2K8 CHEMBL5701 Serine/threonine-protein Kinase TAO3, Human 1
TBK1_HUMAN Q9UHD2 CHEMBL5408 Serine/threonine-protein Kinase TBK1, Human 1
TLK1_HUMAN Q9UKI8 CHEMBL5388 Serine/threonine-protein Kinase Tousled-like 1, Human 1
TLK2_HUMAN Q86UE8 CHEMBL5404 Serine/threonine-protein Kinase Tousled-like 2, Human 1
TNIK_HUMAN Q9UKE5 CHEMBL4527 TRAF2- And NCK-interacting Kinase, Human 1
TNKS2_HUMAN Q9H2K2 CHEMBL6154 Tankyrase-2, Human 1
TSSK1_HUMAN Q9BXA7 CHEMBL6003 Testis-specific Serine/threonine-protein Kinase 1, Human 1
TTK_HUMAN P33981 CHEMBL3983 Dual Specificity Protein Kinase TTK, Human 1
TYRO3_HUMAN Q06418 CHEMBL5314 Tyrosine-protein Kinase Receptor TYRO3, Human 1
UFO_HUMAN P30530 CHEMBL4895 Tyrosine-protein Kinase Receptor UFO, Human 1
ULK1_HUMAN O75385 CHEMBL6006 Serine/threonine-protein Kinase ULK1, Human 1
ULK2_HUMAN Q8IYT8 CHEMBL5435 Serine/threonine-protein Kinase ULK2, Human 1
ULK3_HUMAN Q6PHR2 CHEMBL5047 Serine/threonine-protein Kinase ULK3, Human 1
ULK3_MOUSE Q3U3Q1 CHEMBL3832 ULK3 Kinase, Mouse 1
VGFR1_MOUSE P35969 CHEMBL3516 Vascular Endothelial Growth Factor Receptor 1, Mouse 1
VGFR2_MOUSE P35918 CHEMBL3337 Vascular Endothelial Growth Factor Receptor 2, Mouse 1
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 1
YES_HUMAN P07947 CHEMBL2073 Tyrosine-protein Kinase YES, Human 1
YSK4_HUMAN Q56UN5 CHEMBL6191 SPS1/STE20-related Protein Kinase YSK4, Human 1
Z80344 Z80344 CHEMBL614205 NT2 (Teratocarcinoma Cells) 1

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