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S1PR2_HUMAN - Sphingosine 1-phosphate Receptor Edg-5, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

Sphingosine 1-phosphate Receptor Edg-5, Human (116 Compounds)

Swissprot:
S1PR2_HUMAN
Stitch:
S1PR2_HUMAN
UniProt:
O95136
ChEMBL:
CHEMBL2955
Reactome:
REACT_19231
REACT_18365
PDB:
1ZTI (DOCK)
S1PR2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 116 4 2 0
Binding ≤ 1μM 98 4 2 0
Functional ≤ 10μM 5 0 0 0

Reactome Network (2)

Reactome ID Description Species
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_18365 Lysosphingolipid and LPA receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 28
S1PR1_HUMAN P21453 CHEMBL4333 Sphingosine 1-phosphate Receptor Edg-1, Human 116
S1PR3_HUMAN Q99500 CHEMBL3892 Sphingosine 1-phosphate Receptor Edg-3, Human 112
S1PR4_HUMAN O95977 CHEMBL3230 Sphingosine 1-phosphate Receptor Edg-6, Human 80
S1PR5_HUMAN Q9H228 CHEMBL2274 Sphingosine 1-phosphate Receptor Edg-8, Human 36

Lysosphingolipid and LPA receptors

Uniprot Swissprot Chembl Description Number Shared
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 28
S1PR1_HUMAN P21453 CHEMBL4333 Sphingosine 1-phosphate Receptor Edg-1, Human 116
S1PR3_HUMAN Q99500 CHEMBL3892 Sphingosine 1-phosphate Receptor Edg-3, Human 112
S1PR4_HUMAN O95977 CHEMBL3230 Sphingosine 1-phosphate Receptor Edg-6, Human 80
S1PR5_HUMAN Q9H228 CHEMBL2274 Sphingosine 1-phosphate Receptor Edg-8, Human 36
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
S1PR1_HUMAN P21453 CHEMBL4333 Sphingosine 1-phosphate Receptor Edg-1, Human 487 13 7 2
S1PR3_HUMAN Q99500 CHEMBL3892 Sphingosine 1-phosphate Receptor Edg-3, Human 317 5 4 1
S1PR4_HUMAN O95977 CHEMBL3230 Sphingosine 1-phosphate Receptor Edg-6, Human 206 5 4 0
S1PR5_HUMAN Q9H228 CHEMBL2274 Sphingosine 1-phosphate Receptor Edg-8, Human 207 8 6 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
S1PR1_HUMAN P21453 CHEMBL4333 Sphingosine 1-phosphate Receptor Edg-1, Human 116
S1PR3_HUMAN Q99500 CHEMBL3892 Sphingosine 1-phosphate Receptor Edg-3, Human 112
S1PR4_HUMAN O95977 CHEMBL3230 Sphingosine 1-phosphate Receptor Edg-6, Human 74
S1PR5_HUMAN Q9H228 CHEMBL2274 Sphingosine 1-phosphate Receptor Edg-8, Human 36
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 28
SPHK1_HUMAN Q9NYA1 CHEMBL4394 Sphingosine Kinase 1, Human 1