UCSF

Solute Carrier Family 22 Member 1, Human (5 Compounds)

Swissprot:
S22A1_HUMAN
Stitch:
S22A1_HUMAN
UniProt:
O15245
ChEMBL:
CHEMBL5685
Reactome:
REACT_120801
REACT_20506
REACT_13583
REACT_15418
REACT_22357
PDB:
SLC22A1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 5 5 5 5
Binding ≤ 1μM 0 0 0 0

Reactome Network (5)

Reactome ID Description Species
REACT_120801 Abacavir transmembrane transport Homo sapiens
REACT_20506 Na+/Cl- dependent neurotransmitter transporters Homo sapiens
REACT_13583 Neurotransmitter Clearance In The Synaptic Cleft Homo sapiens
REACT_15418 Norepinephrine Neurotransmitter Release Cycle Homo sapiens
REACT_22357 Organic cation transport Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
S22A6_HUMAN Q4U2R8 CHEMBL1641347 Solute Carrier Family 22 Member 6, Human 1 1 1 1
S22AC_HUMAN Q96S37 CHEMBL6120 Solute Carrier Family 22 Member 12, Human 21 3 3 2

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 3
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 1
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 1
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 1
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 1
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 1
ABCC8_HUMAN Q09428 CHEMBL2071 Sulfonylurea Receptor 1, Human 1
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 1
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 1
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 1
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 1
ADA1B_MESAU P18841 CHEMBL3122 Alpha-1b Adrenergic Receptor, Mesau 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 1
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 1
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 1
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 1
ADA2A_MOUSE Q01338 CHEMBL4075 Alpha-2a Adrenergic Receptor, Mouse 1
ADA2A_PIG P18871 CHEMBL2350 Alpha-2a Adrenergic Receptor, Pig 1
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 1
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 1
ADA2B_MOUSE P30545 CHEMBL2405 Alpha-2b Adrenergic Receptor, Mouse 1
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 1
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 1
ADA2C_MOUSE Q01337 CHEMBL4826 Alpha-2c Adrenergic Receptor, Mouse 1
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 1
CAC1C_HUMAN Q13936 CHEMBL1940 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human 1
CAC1C_RABIT P15381 CHEMBL2830 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rabit 1
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 1
CAC1D_HUMAN Q01668 CHEMBL4138 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human 1
CAC1D_RAT P27732 CHEMBL4132 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat 1
CAC1S_RAT Q02485 CHEMBL4108 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Rat 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1
MRP1_HUMAN P33527 CHEMBL3004 Multidrug Resistance-associated Protein 1, Human 1
MT3_HUMAN P25713 CHEMBL1250357 Metallothionein-3, Human 1
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 1
P97706_RAT P97706 CHEMBL4957 Sodium Channel Protein Type VI Alpha Subunit, Rat 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN5A_RAT P15389 CHEMBL3866 Sodium Channel Protein Type V Alpha Subunit, Rat 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1
TOP2A_HUMAN P11388 CHEMBL1806 DNA Topoisomerase II Alpha, Human 1
TOP2B_HUMAN Q02880 CHEMBL3396 DNA Topoisomerase II Beta, Human 1
TSPO_RAT P16257 CHEMBL4552 Peripheral-type Benzodiazepine Receptor, Rat 1
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1