UCSF

Sigma-1 Receptor, Guinea Pig (823 Compounds)

Swissprot:
SGMR1_CAVPO
Stitch:
SGMR1_CAVPO
UniProt:
Q60492
ChEMBL:
CHEMBL4153

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 823 43 14 13
Binding ≤ 1μM 697 42 14 13

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 1,873 230 56 56
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 205 11 8 7
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 1,157 146 42 57

Clustered By Gene (0)

Clustered By Organism (5)

Code Description Substances Purchasable Natural In Man
SGMR1-1-E Sigma Opioid Receptor (cluster #1 Of 6), Eukaryotic 3,485 332 79 95
SGMR1-2-E Sigma Opioid Receptor (cluster #2 Of 6), Eukaryotic 15 6 3 3
SGMR1-3-E Sigma Opioid Receptor (cluster #3 Of 6), Eukaryotic 135 9 7 4
SGMR1-4-E Sigma Opioid Receptor (cluster #4 Of 6), Eukaryotic 193 26 3 3
SGMR1-5-E Sigma Opioid Receptor (cluster #5 Of 6), Eukaryotic 1 1 1 0
SGMR1-6-E Sigma Opioid Receptor (cluster #6 Of 6), Eukaryotic 42 5 1 1
Uniprot Swissprot Chembl Description Number Shared
EBP_CAVPO Q60490 CHEMBL5525 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Guinea Pig 94
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 66
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 54
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 51
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 47
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 45
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 39
Z104297 Z104297 CHEMBL1907603 Glutamate NMDA Receptor; GRIN1/GRIN2B 30
VACHT_HUMAN Q16572 CHEMBL4767 Vesicular Acetylcholine Transporter, Human 29
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 27
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 26
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 24
VACHT_TORCA P81721 CHEMBL3313 Vesicular Acetylcholine Transporter, Torca 22
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 20
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 18
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 16
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 15
AP2S1_RAT P62744 CHEMBL1697667 AP-2 Complex Subunit Sigma, Rat 9
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 9
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 9
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 7
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 7
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 7
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 7
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 7
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 7
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 6
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 6
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 5
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 5
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 5
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 5
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 5
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 5
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 5
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 5
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 5
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 5
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 4
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 4
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 4
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 4
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 4
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 4
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 4
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 3
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 3
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 3
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 3
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 3
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 3
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 3
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 3
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 3
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 3
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 3
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 3
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 2
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 2
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 2
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 2
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 2
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 2
NMD3B_RAT Q8VHN2 CHEMBL282 Glutamate [NMDA] Receptor Subunit 3B, Rat 2
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 2
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 2
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 2
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 2
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 2
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 2
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 2
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 2
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 1
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 1
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 1
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 1
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 1
5HT2A_PIG P50129 CHEMBL2490 Serotonin 2a (5-HT2a) Receptor, Pig 1
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 1
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 1
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 1
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 1
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 1
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 1
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 1
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 1
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 1
ANDR_MOUSE P19091 CHEMBL3056 Androgen Receptor, Mouse 1
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 1
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 1
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
ESR1_RAT P06211 CHEMBL2724 Estrogen Receptor Alpha, Rat 1
ESR2_RAT Q62986 CHEMBL3021 Estrogen Receptor Beta, Rat 1
FABPL_RAT P02692 CHEMBL5738 Fatty Acid-binding Protein, Liver, Rat 1
GCR_HUMAN P04150 CHEMBL2034 Glucocorticoid Receptor, Human 1
MCR_HUMAN P08235 CHEMBL1994 Mineralocorticoid Receptor, Human 1
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 1
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 1
OPRK_MOUSE P33534 CHEMBL4329 Kappa Opioid Receptor, Mouse 1
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 1
PRGR_CHICK P07812 CHEMBL3304 Progesterone Receptor, Chick 1
PRGR_HUMAN P06401 CHEMBL208 Progesterone Receptor, Human 1
PRGR_RABIT P06186 CHEMBL3456 Progesterone Receptor, Rabit 1
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 1
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 1
S5A1_RAT P24008 CHEMBL3422 Steroid 5-alpha-reductase 1, Rat 1
S5A2_RAT P31214 CHEMBL5099 Steroid 5-alpha-reductase 2, Rat 1
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN1A_RAT P04774 CHEMBL4906 Sodium Channel Protein Type I Alpha Subunit, Rat 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN2A_RAT P04775 CHEMBL3399 Sodium Channel Protein Type II Alpha Subunit, Rat 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN3A_RAT P08104 CHEMBL4966 Sodium Channel Protein Type III Alpha Subunit, Rat 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1
SCN8A_RAT O88420 CHEMBL2752 Sodium Channel Protein Type VIII Alpha Subunit, Rat 1
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1

Most Common Rings