UCSF

Sphingosine Kinase 1, Human (85 Compounds)

Swissprot:
SPHK1_HUMAN
Stitch:
SPHK1_HUMAN
UniProt:
Q9NYA1
ChEMBL:
CHEMBL4394
Reactome:
REACT_16907
REACT_115810
REACT_228024
PDB:
SPHK1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 85 5 2 0
Binding ≤ 1μM 43 0 0 0

Reactome Network (3)

Reactome ID Description Species
REACT_16907 Association of TriC/CCT with target proteins during biosynthesis Homo sapiens
REACT_115810 Sphingolipid de novo biosynthesis Homo sapiens
REACT_228024 VEGFR2 mediated cell proliferation Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
SPHK2_HUMAN Q9NRA0 CHEMBL3023 Sphingosine Kinase 2, Human 4
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SPHK2_HUMAN Q9NRA0 CHEMBL3023 Sphingosine Kinase 2, Human 4 1 1 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
SPHK1-1-E Sphingosine Kinase 1 (cluster #1 Of 2), Eukaryotic 79 3 0 0
SPHK1-2-E Sphingosine Kinase 1 (cluster #2 Of 2), Eukaryotic 8 2 2 0
Uniprot Swissprot Chembl Description Number Shared
SPHK2_MOUSE Q9JIA7 CHEMBL1075305 Sphingosine Kinase 2, Mouse 11
SPHK2_HUMAN Q9NRA0 CHEMBL3023 Sphingosine Kinase 2, Human 4
CETP_HUMAN P11597 CHEMBL3572 Cholesteryl Ester Transfer Protein, Human 1
KAPCA_RAT P27791 CHEMBL3390 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rat 1
KPCA_RAT P05696 CHEMBL2855 Protein Kinase C Alpha, Rat 1
KPCB_RAT P68403 CHEMBL3020 Protein Kinase C Beta, Rat 1
KPCD_RAT P09215 CHEMBL3633 Protein Kinase C Delta, Rat 1
KPCE_RAT P09216 CHEMBL3424 Protein Kinase C Epsilon, Rat 1
KPCG_RAT P63319 CHEMBL3604 Protein Kinase C Gamma, Rat 1
KPCL_RAT Q64617 CHEMBL3990 Protein Kinase C Eta, Rat 1
KPCT_RAT Q9WTQ0 CHEMBL4563 Protein Kinase C Theta, Rat 1
S1PR1_HUMAN P21453 CHEMBL4333 Sphingosine 1-phosphate Receptor Edg-1, Human 1
S1PR2_HUMAN O95136 CHEMBL2955 Sphingosine 1-phosphate Receptor Edg-5, Human 1
S1PR3_HUMAN Q99500 CHEMBL3892 Sphingosine 1-phosphate Receptor Edg-3, Human 1
S1PR4_HUMAN O95977 CHEMBL3230 Sphingosine 1-phosphate Receptor Edg-6, Human 1
S1PR5_HUMAN Q9H228 CHEMBL2274 Sphingosine 1-phosphate Receptor Edg-8, Human 1

Most Common Rings