UCSF

Coagulation Factor III, Human (363 Compounds)

Swissprot:
TF_HUMAN
Stitch:
TF_HUMAN
UniProt:
P13726
ChEMBL:
CHEMBL4081
Reactome:
REACT_1573
PDB:
1AHW (DOCK)
1BOY (DOCK)
1DAN (DOCK)
1FAK (DOCK)
1J9C (DOCK)
1JPS (DOCK)
1NL8 (DOCK)
1O5D (DOCK)
1TFH (DOCK)
1UJ3 (DOCK)
1W0Y (DOCK)
1W2K (DOCK)
1WQV (DOCK)
1WSS (DOCK)
1WTG (DOCK)
1WUN (DOCK)
1WV7 (DOCK)
1Z6J (DOCK)
2A2Q (DOCK)
2AEI (DOCK)
2AER (DOCK)
2B7D (DOCK)
2B8O (DOCK)
2C4F (DOCK)
2CEF (DOCK)
2CEH (DOCK)
2CEZ (DOCK)
2CFJ (DOCK)
2EC9 (DOCK)
2F9B (DOCK)
2FIR (DOCK)
2FLB (DOCK)
2FLR (DOCK)
2HFT (DOCK)
2PUQ (DOCK)
2ZP0 (DOCK)
2ZWL (DOCK)
2ZZU (DOCK)
3ELA (DOCK)
F3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 363 4 2 3
Binding ≤ 1μM 300 2 1 2

Reactome Network (1)

Reactome ID Description Species
REACT_1573 Extrinsic Pathway Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 102
FA7_HUMAN P08709 CHEMBL3991 Coagulation Factor VII, Human 301
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
TF65_HUMAN Q04206 CHEMBL5533 Nuclear Factor NF-kappa-B P65 Subunit, Human 45 15 4 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
FA7_HUMAN P08709 CHEMBL3991 Coagulation Factor VII, Human 301
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 148
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 102
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 33
TRY2_HUMAN P07478 CHEMBL3159 Trypsin II, Human 30
TRY3_HUMAN P35030 CHEMBL4551 Trypsin III, Human 30
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 23
HDA10_HUMAN Q969S8 CHEMBL5103 Histone Deacetylase 10, Human 3
HDA11_HUMAN Q96DB2 CHEMBL3310 Histone Deacetylase 11, Human 3
HDAC1_HUMAN Q13547 CHEMBL325 Histone Deacetylase 1, Human 3
HDAC2_HUMAN Q92769 CHEMBL1937 Histone Deacetylase 2, Human 3
HDAC3_HUMAN O15379 CHEMBL1829 Histone Deacetylase 3, Human 3
HDAC4_HUMAN P56524 CHEMBL3524 Histone Deacetylase 4, Human 3
HDAC5_HUMAN Q9UQL6 CHEMBL2563 Histone Deacetylase 5, Human 3
HDAC6_HUMAN Q9UBN7 CHEMBL1865 Histone Deacetylase 6, Human 3
HDAC7_HUMAN Q8WUI4 CHEMBL2716 Histone Deacetylase 7, Human 3
HDAC8_HUMAN Q9BY41 CHEMBL3192 Histone Deacetylase 8, Human 3
HDAC9_HUMAN Q9UKV0 CHEMBL4145 Histone Deacetylase 9, Human 3
Q9XYC7_PLAFA Q9XYC7 CHEMBL5541 Histone Deacetylase, Plafa 3
HDAH_ALCSD Q70I53 CHEMBL6017 Histone Deacetylase-like Amidohydrolase, Alcsd 2
NCOR2_HUMAN Q9Y618 CHEMBL5949 Nuclear Receptor Corepressor 2, Human 2
B1WBY8_RAT B1WBY8 CHEMBL4705 Histone Deacetylase 2, Rat 1
FA12_HUMAN P00748 CHEMBL2821 Coagulation Factor XII, Human 1
HDA11_MOUSE Q91WA3 CHEMBL5143 Histone Deacetylase 11, Mouse 1
HDAC1_CHICK P56517 CHEMBL4582 Histone Deacetylase 1, Chick 1
HDAC1_MOUSE O09106 CHEMBL4001 Histone Deacetylase 1, Mouse 1
HDAC1_RAT Q4QQW4 CHEMBL2915 Histone Deacetylase 1, Rat 1
HDAC2_CHICK P56519 CHEMBL4583 Histone Deacetylase 2, Chick 1
HDAC2_MOUSE P70288 CHEMBL4238 Histone Deacetylase 2, Mouse 1
HDAC3_CHICK P56520 CHEMBL4584 Histone Deacetylase 3, Chick 1
HDAC3_MOUSE O88895 CHEMBL5142 Histone Deacetylase 3, Mouse 1
HDAC3_RAT Q6P6W3 CHEMBL2628 Histone Deacetylase 3, Rat 1
HDAC4_CHICK P83038 CHEMBL5599 Histone Deacetylase 4, Chick 1
HDAC4_RAT Q99P99 CHEMBL2874 Histone Deacetylase 4, Rat 1
HDAC5_MOUSE Q9Z2V6 CHEMBL2768 Histone Deacetylase 5, Mouse 1
HDAC6_MOUSE Q9Z2V5 CHEMBL2878 Histone Deacetylase 6, Mouse 1
HDAC7_MOUSE Q8C2B3 CHEMBL4219 Histone Deacetylase 7, Mouse 1
HDAC7_RAT Q99P96 CHEMBL2914 Histone Deacetylase 7, Rat 1
HDAC8_MOUSE Q8VH37 CHEMBL2347 Histone Deacetylase 8, Mouse 1
HDAC9_MOUSE Q99N13 CHEMBL5204 Histone Deacetylase 9, Mouse 1
KLKB1_HUMAN P03952 CHEMBL2000 Plasma Kallikrein, Human 1
Q5RJZ2_RAT Q5RJZ2 CHEMBL4025 Histone Deacetylase 5, Rat 1
Q7YY07_CRYPV Q7YY07 CHEMBL4740 Histone Deacetylase, Crypv 1
Q7YY76_CRYPV Q7YY76 CHEMBL3626 Histone Deacetylase, Crypv 1
Q94F81_MAIZE Q94F81 CHEMBL4919 Histone Deacetylase HD2, Maize 1
Q99P97_RAT Q99P97 CHEMBL3101 Histone Deacetylase 6, Rat 1
Q9ZTP8_MAIZE Q9ZTP8 CHEMBL3541 Histone Deacetylase HD1B, Maize 1
SF3B3_HUMAN Q15393 CHEMBL1250378 Splicing Factor 3B Subunit 3, Human 1
UROK_HUMAN P00749 CHEMBL3286 Urokinase-type Plasminogen Activator, Human 1