ZINC 12

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Swissprot:: THA_HUMAN
Stitch:: THA_HUMAN
UniProt:: P10827
ChEMBL:: CHEMBL1860
Reactome:: REACT_15525
PDB:: 1NAV (DOCK); 2H77 (DOCK); 2H79 (DOCK); 3HZF (DOCK); 3ILZ (DOCK); 3JZB (DOCK); THRA

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	203	8	4	7
Binding ≤ 1μM	128	6	4	7
Functional ≤ 10μM	32	1	0	2

Reactome ID	Description	Species
REACT_15525	Nuclear Receptor transcription pathway	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
ANDR_HUMAN	P10275	CHEMBL1871	Androgen Receptor, Human	2
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	1
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	1
PRGR_HUMAN	P06401	CHEMBL208	Progesterone Receptor, Human	2
THB_HUMAN	P10828	CHEMBL1947	Thyroid Hormone Receptor Beta-1, Human	217

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
THA_RAT	P63059	CHEMBL4823	Thyroid Hormone Receptor Alpha, Rat	17	1	1	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
THAS_HUMAN	P24557	CHEMBL1835	Thromboxane-A Synthase, Human	972	36	9	8

Uniprot	Swissprot	Chembl	Description	Number Shared
THB_HUMAN	P10828	CHEMBL1947	Thyroid Hormone Receptor Beta-1, Human	217
Z80092	Z80092	CHEMBL614031	CHO-K1 (Ovarian Cells)	6
THB_RAT	P18113	CHEMBL3917	Thyroid Hormone Receptor Beta-1, Rat	4
ANDR_HUMAN	P10275	CHEMBL1871	Androgen Receptor, Human	2
PRGR_HUMAN	P06401	CHEMBL208	Progesterone Receptor, Human	2
THA_RAT	P63059	CHEMBL4823	Thyroid Hormone Receptor Alpha, Rat	2
CYSP_TRYCR	P25779	CHEMBL3563	Cruzipain, Trycr	1
EBP_HUMAN	Q15125	CHEMBL4931	3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human	1
ERG2_YEAST	P32352	CHEMBL3224	C-8 Sterol Isomerase, Yeast	1
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	1
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	1
FDFT_HUMAN	P37268	CHEMBL3338	Squalene Synthetase, Human	1
GCR_HUMAN	P04150	CHEMBL2034	Glucocorticoid Receptor, Human	1
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	1
KCNQ1_CAVPO	O70344	CHEMBL5135	Voltage-gated Potassium Channel Subunit Kv7.1, Guinea Pig	1
LEF_BACAN	P15917	CHEMBL4372	Anthrax Lethal Factor, Bacan	1
MCR_HUMAN	P08235	CHEMBL1994	Mineralocorticoid Receptor, Human	1
MDR1_HUMAN	P08183	CHEMBL4302	P-glycoprotein 1, Human	1
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	1
Z104301	Z104301	CHEMBL1907607	GABA-A Receptor; Anion Channel	1
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA Receptor	1
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	1