UCSF

Thyroid Hormone Receptor Beta-1, Human (340 Compounds)

Swissprot:
THB_HUMAN
Stitch:
THB_HUMAN
UniProt:
P10828
ChEMBL:
CHEMBL1947
Reactome:
REACT_15525
PDB:
1BSX (DOCK)
1N46 (DOCK)
1NAX (DOCK)
1NQ0 (DOCK)
1NQ1 (DOCK)
1NQ2 (DOCK)
1NUO (DOCK)
1Q4X (DOCK)
1R6G (DOCK)
1XZX (DOCK)
1Y0X (DOCK)
2J4A (DOCK)
2NLL (DOCK)
2PIN (DOCK)
3D57 (DOCK)
3GWS (DOCK)
3IMY (DOCK)
3JZC (DOCK)
THRB

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 340 9 4 10
Binding ≤ 1μM 207 6 4 9
Functional ≤ 10μM 32 1 0 2

Reactome Network (1)

Reactome ID Description Species
REACT_15525 Nuclear Receptor transcription pathway Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 1
PRGR_HUMAN P06401 CHEMBL208 Progesterone Receptor, Human 1
THA_HUMAN P10827 CHEMBL1860 Thyroid Hormone Receptor Alpha, Human 217
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
THB_RAT P18113 CHEMBL3917 Thyroid Hormone Receptor Beta-1, Rat 65 2 4 2

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
THA_HUMAN P10827 CHEMBL1860 Thyroid Hormone Receptor Alpha, Human 217
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 17
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 10
Z80092 Z80092 CHEMBL614031 CHO-K1 (Ovarian Cells) 6
THB_RAT P18113 CHEMBL3917 Thyroid Hormone Receptor Beta-1, Rat 4
THA_RAT P63059 CHEMBL4823 Thyroid Hormone Receptor Alpha, Rat 2
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 1
CYSP_TRYCR P25779 CHEMBL3563 Cruzipain, Trycr 1
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 1
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 1
FDFT_HUMAN P37268 CHEMBL3338 Squalene Synthetase, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
KCNQ1_CAVPO O70344 CHEMBL5135 Voltage-gated Potassium Channel Subunit Kv7.1, Guinea Pig 1
LEF_BACAN P15917 CHEMBL4372 Anthrax Lethal Factor, Bacan 1
MCR_HUMAN P08235 CHEMBL1994 Mineralocorticoid Receptor, Human 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1
PRGR_HUMAN P06401 CHEMBL208 Progesterone Receptor, Human 1
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 1
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1